How can we improve the treatment of thrombosis, reduce the disease’s impact and spend less money while we’re at it? This is what Erik Klok, Professor of Internal Medicine and an internist, is researching. He will discuss it in depth in his inaugural lecture on 10 March.

Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…

Eleven lecturers from Leiden University have been awarded Comenius grants that will allow them to work with their teams on an innovation project within their own teaching. They have been awarded three grants of 100,000 euros within the Senior Fellows programme and four grants of 50,000 euros within…

Lecture, Center of Computational Life Sciences

Never before has so much research been carried out on the therapeutic effect of psychedelic drugs. Researchers at the LIBC Public Day are happy about the effect the drugs can have on depression, anxiety and PTSS, but at the same time they have some doubts. ‘The hype is bound to crash before long.’

PhD candidate Sibel Bahtiri is one of the new Faces of Science. In videos and blogs, she will show what life is like as a young researcher.

The European PANVIPREP research project started at the Leiden University Medical Center on 11 March. The participants are virologists, biochemists and pharmacists from 14 European countries. Their mission is to develop antiviral drugs to protect Europe during pandemics. At least two such antivirals…

To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

Social Psychologist Angelo Romano have been awarded the Association for Psychological Science (ASP) Rising Star designation. This award is presented to outstanding APS members in the earliest stages of their research career post-PhD.

Freezers set three degrees higher, a recycling bin for plastic petri dishes or timer switches installed on equipment: a growing number of Leiden University laboratories are taking small – but effective – steps to reduce their environmental impact, via the internationally recognized Laboratory Efficiency…

PhD candidates Mohammed Saleh and Berfin Gülave (Division of Systems Pharmacology and Pharmacy) published their research paper on “Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice”.

On the 8th of March the first "introduction to entrepreneurship" boot camp was held at PLNT specifically for PhD researchers at the LACDR. During the two hour block topics such as "the core of entrepreneurship", "spotting opportunities" and "what is your value proposition" were discussed.

Prof. dr. Douwe Breimer, emeritus Professor of Pharmacology, former Rector Magnificus and founder of LACDR has established a foundation to stimulate, support, and promote scientific meetings in the field of Pharmacology. Particularly those concerned with fundamental research and mathematical modelling…

From self-driving cars to innovative drug development, artificial intelligence (AI) is going to fundamentally change our lives in a variety of ways.

Should we ban snack bars from neighbourhoods where residents are overweight or have diabetes? At the Common Sense about Health knowledge festival, scientists, civil servants and other professionals discussed how South Holland can become healthier. The Healthy Society Map makes it clear where there are…

The whole world is waiting anxiously for sufficient supplies of coronavirus vaccines. As Launch Navigator at Pfizer, alumnus Dennis de Mik must help ensure that the Netherlands receives 19.8 million doses of the Pfizer/BioNTech vaccine. How is he going about this and how has his Bio-Pharmaceutical Sciences…

Today, ESA’s Gaia mission releases its new treasure trove of data about our home galaxy. Astronomers, led by the Leiden astronomer Anthony Brown, describe strange ‘starquakes’, stellar DNA, asymmetric motions and other fascinating insights in this most detailed Milky Way survey to date.

From 11 to 17 September, Leiden will be all about art and science. What can the combination of these two domains do for us? And how can cooperation between them be strengthened? Several public events and a brand new symposium for specialists should answer these questions.

Nanomaterials can pass much further along the food chain than was previously thought. The particles can change shape and size in each organism, enabling them to pass on to the next one in the chain. Researchers from the Institute of Environmental Sciences discovered this accidentally when using a novel…

Leiden professor of Cellular Immunology of Parasitic Infections Maria Yazdanbakhsh receives the prestigious NWO Spinoza Prize this year. This, in many ways, border-crossing scientist contributes with her research to more effective vaccines against parasitic infections and better medication for inflammatory…

Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…

A European team of astronomers has discovered the largest stellar black hole in the Milky Way. It is more than thirty times as massive as our sun and is located in the constellation of Aquila, about two thousand light-years from Earth. The astronomers stumbled upon the black hole by chance while preparing…

For the past 2 years, Dr Letty ten Harkel has been jointly running an excavation project of a suspected Roman villa site on the Balearic island of Mallorca with colleagues Dr Antoni Puig Palerm and Ritchie Kolvers, MA. The project was recently awarded a LUF Chastelain-Nobach fund to explore the extend…

The 50th Top 450 entry has now been published. In the run-up to the university’s 450th anniversary, we are compiling our Top 450. What is your favourite?

Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?

What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…

Hans Ulrich Scherer is Professor of Rheumatology, in particular Translational Rheumatology. He wants to build bridges between research and clinical practice and between departments and organisations at home and abroad. Scherer will give his inaugural lecture next Friday. ‘To make progress, we have to…

Social

This practical guide is aimed at PhD candidates, Research Master Students, and early-career researchers from all academic disciplines. The instructions in the guide intend to inspire young researchers and to help them practice Open Science, by sharing all aspects of research as open possible.

John Boy will be an Urban Citizen Fellow for the next academic year with his research project Urban Citizenship and Emerging Critical Technical Practices in Amsterdam. He will research the question: What critical technical practices are technologists in Amsterdam experimenting with, and how they can…

Education, Research

When we think of unethical medical experiments, we tend to think first of Nazi Germany. What is less well known is that experiments were also carried out in colonised areas without the explicit consent of the test subject. University lecturer Fenneke Sysling has received a European grant to research…

Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.

Gerard van Westen has received the KNCV Gold Medal, the most important Dutch award for chemists under 40. 'It's a huge honour,' says the professor of AI and medicinal chemistry. 'I am now part of the group of people I was always impressed by.'

As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…

On July 28, 2022, our dear colleague Daniëlle Hamstra passed away after a short sickbed. Daniëlle had been associated with the Clinical Psychology Section since 2010, initially as a student in the research master's program and subsequently as a lecturer and PhD candidate.

Last month, research by the National Institute for Public Health and the Environment (RIVM) revealed that more than half of students in higher professional education and at universities experience psychological complaints and emotional exhaustion, and that a quarter of them suffer from anhedonia (loss…

The steady decline in lethal gun violence in the EU came to halt in 2012 and some countries, such as Sweden, have even noticed an increase since then. An arms race among drug criminals and an increase in the availability of illegal firearms could lead to more criminal and gun violence. This is one of…

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.