How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.

The steady decline in lethal gun violence in the EU came to halt in 2012 and some countries, such as Sweden, have even noticed an increase since then. An arms race among drug criminals and an increase in the availability of illegal firearms could lead to more criminal and gun violence. This is one of…

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

On July 28, 2022, our dear colleague Daniëlle Hamstra passed away after a short sickbed. Daniëlle had been associated with the Clinical Psychology Section since 2010, initially as a student in the research master's program and subsequently as a lecturer and PhD candidate.

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

Last month, research by the National Institute for Public Health and the Environment (RIVM) revealed that more than half of students in higher professional education and at universities experience psychological complaints and emotional exhaustion, and that a quarter of them suffer from anhedonia (loss…

Giving an incorrect answer as a student in a packed lecture hall can be nerve-wracking. But with Pharmacology teacher Rob van Wijk, you don’t need to worry about that. ‘He creates a comfortable and safe atmosphere,’ his students say. They have nominated him for the Leiden Science Teacher Award.

Instant messaging app Telegram is not faring well in the news – the reason being the illicit activities occurring on the platform. Professor Bart Custers helped Dutch current affairs programme ‘EenVandaag’ respond to questions about the platform.

How can we diagnose the life-threatening condition sepsis in premature babies as quickly and accurately as possible? That is what PhD student Manchu Thangavelu from the Leiden Academic Centre for Drug Research (LACDR) wants to figure out.

Education

On 25 May 2024, our much-loved former colleague prof.dr.dr.h.c.mult Hans E. Junginger passed away.

On Friday 2 June 2023, Vincent Delhomme, Assistant professor at the Europe Institute at Leiden Law School, successfully defended his PhD thesis entitled : ‘Regulating lifestyle risks in EU law: Promoting health in a diverse market’.

On Wednesday 16 June 2021, Karim Khan was sworn in at the International Criminal Court (ICC) in The Hague. Experts say this is no easy time to join the ICC.

Ad IJzerman, Emeritus Professor of Pharmacochemistry, was made a Knight of the Order of the Lion of the Netherlands on 26 April. He was presented with the royal honour by Mayor Elbert Roest in the town hall in Bloemendaal.

Natalia Ortiz (Division of Drug Discovery and Safety) has been awarded the 2019-2020 PhD-thesis prize by the Division of Medicinal Chemistry & Chemical Biology, from the Royal Netherlands Chemical Society (KNCV-MCCB). The KNCV-MCCB thesis prize is a biannual award which is granted to the best PhD thesis…

The European Food Safety Authority (EFSA) has awarded a €1.6M contract to an LACDR-led consortium to assess how sensitivity to toxicity caused by chemicals varies among individual people. Currently these toxicodynamic differences are an unknown source of uncertainty when carrying out risk assessment…

Eleven researchers of the Faculty of Science are on the 2021 Highly Cited Researchers list of Clarivate Analytics. Only 0.1 per cent of researchers are included in this list, literally making them one in a thousand.

We are congratulating Maaike van der Lee, PhD candidate at LUMC-KFT, for winning the national PhD competition 2021 at the FIGON Dutch Medicine Days. During this national competition, 8 researchers from the major university cities in the Netherlands present their work in the field of innovative medicine…

Florian Herrendorf has won the Fruin Prize 2023. His thesis was chosen out of 11 nominees as the best master's thesis in history studies.

It was not until 1878 that the first female students enrolled at Leiden University, but the discussion on whether women were suited to study was by no means over. 8 March is International Women's Day. BBC correspondente Kim Ghattas will deliver a lecture on 6 March on the struggle by Arabic women for…

‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.

An impressive 21 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

PhD

Lecture, Research seminar 1000-1800

Lecture, Research Seminar Europe 1000-1800

Lecture, Research Seminar Europe 1000-1800

Lecture, Research seminar 1000-1800

Study information

Lecture, Research seminar 1000-1800

PhD defence

Lecture, Research seminar 1000-1800

Digitale medische technologie kan een belangrijke bijdrage leveren aan betaalbare zorg en het oplossen van het tekort aan zorgpersoneel. Maar hoe weet je of een innovatie daadwerkelijk waarde toevoegt aan het zorgsysteem?

On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…

Rawi Ramautar will be the new Programme Director of the bachelor of Bio-Pharmaceutical Sciences starting September 1. The appointment is for four years. Ramautar succeeds Erik Danen, who has held the position since 2019.

The number of life sentences in the Netherlands is rising sharply. This is a clear response to the serious drugs violence and brutal attacks on our rule of law. However, criminal justice experts do not believe that this will deter future offenders from carrying out liquidations.

In a project funded by the John Templeton Foundation to the group of Micha Drukker, scientists will produce stem cells from short and long living understudied species to model cellular and organismal lifespan.

As of 1 September Miranda van Eck will be the new Scientific Director of the Leiden Academic Centre for Drug Research. She succeeds Hubertus Irth, who led the institute since 2016. Van Eck has been appointed for a period of four years.

Suzanne van der Pluijm will be appointed Executive Director and Member of the Board of the Faculty of Science with effect from 1 June 2022. She succeeds Ed van den Berg, who has held this position on an interim basis since 1 September 2021 .

Stadswandeling

How can parents avoid passing on stress and mental health problems to their children? Professor of Stress-Related Psychopathology Bernet Elzinga develops simple interventions to help both parents and young people. For her research, she has been awarded the Spinoza Prize, the highest academic honour…

Gilles van Wezel will step down as Scientific Director (SD) of the Institute of Biology Leiden (IBL) as of June 17th. He has held this position since September 2018. Van Wezel will be temporarily succeeded by Hubertus Irth, the current SD of the Leiden Academic Centre for Drug Research (LACDR). Irth…

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

Armed with sunglasses, a thick layer of sunscreen and several bottles of water, over 3,300 students have arrived in Leiden for their introduction week. The start of the 55th EL CID happened to be on the hottest day of the year.

Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…