When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…

Social

John Boy will be an Urban Citizen Fellow for the next academic year with his research project Urban Citizenship and Emerging Critical Technical Practices in Amsterdam. He will research the question: What critical technical practices are technologists in Amsterdam experimenting with, and how they can…

Education, Research

Last month, research by the National Institute for Public Health and the Environment (RIVM) revealed that more than half of students in higher professional education and at universities experience psychological complaints and emotional exhaustion, and that a quarter of them suffer from anhedonia (loss…

The right medicine in the right dosage for every patient, that is something medical science aspires. 'Personalised medicine' is the term for that. But it does require a lot of research with patient data and that can be hard to get due to privacy legislation. Researchers Laura Zwep and Coen van Hasselt…

Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.

As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.

The steady decline in lethal gun violence in the EU came to halt in 2012 and some countries, such as Sweden, have even noticed an increase since then. An arms race among drug criminals and an increase in the availability of illegal firearms could lead to more criminal and gun violence. This is one of…

When we think of unethical medical experiments, we tend to think first of Nazi Germany. What is less well known is that experiments were also carried out in colonised areas without the explicit consent of the test subject. University lecturer Fenneke Sysling has received a European grant to research…

Due to the increasing resistance to certain antibiotics, the life-threatening condition sepsis is becoming harder to treat. For her PhD project, Leiden pharmacologist Feiyan Liu used mathematical modeling to find out how antibiotics can be used more effectively to cure sepsis.

Two research groups involving Leiden University have been awarded a major European grant, the ERC Synergy Grant. This for research on the development of membranes that can clean water and purify medical drugs and research on the biological clock in certain bacteria.

Education

How can we diagnose the life-threatening condition sepsis in premature babies as quickly and accurately as possible? That is what PhD student Manchu Thangavelu from the Leiden Academic Centre for Drug Research (LACDR) wants to figure out.

Lecture

Safe use of IT

Safe use of IT

Medici kunnen veel repareren, maar ziekte voorkomen of uitstellen is beter. Daarvoor is vaak leefstijlverandering nodig en dat blijkt lastig. Gezondheidswetenschappers Sandra van Dijk (Universiteit Leiden) en Valentijn Visch (TU Delft) doen onderzoek naar de vraag hoe je mensen kunt helpen met gedragsverandering…

PhD

This Thursday, January 18th 2024, our esteemed colleague Jan Zaanen passed away. Jan was one of our star scientists, larger than life, with an unabashed, boisterous drive for the best of physics at the Institute Lorentz, at the Leiden Institute of Physics and in the full international scientific community.…

Recently, we have witnessed an increased interest of the public and media in the hidden world of underwater archaeology sparked by the identification of a shipwreck as "Klein Hollandia". The research was a joint effort of a team of British and Dutch maritime archaeologists with one familiar face from…

The popular-science book 'Doggerland. Lost World under the North Sea' has been nominated for the EAA Book Prize 2023, awarded annually by the European Association of Archaeologists. At the moment, the book is among 10 publications shortlisted for the prize, with the winner being announced in August…

In exactly 450 days’ time, on 8 February 2025, it is the university’s 450th anniversary. We are obviously going to celebrate this with our students, staff and friends. Do you have any ideas for this celebration?

Since the publication of the article in the interdisciplinary journal Nature, over 200 news outlets have showcased the pioneering research.

Leiden archaeologists have been digging into the municipality of Oss’s past for 50 years now and students have gained their first experience of fieldwork there. What is the result of half a century of research and teaching? Archaeologist Richard Jansen and his students take us to the largest excavation…

Few people would associate the name Anton de Kom with Leiden. Yet the Surinamese freedom fighter is the subject of an exhibition at Museum De Lakenhal.

With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…

Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.

By chance, computer scientist Hans-Dieter Hiep (Leiden Institute of Advanced Computer Science and Centrum Wiskunde & Informatica) discovered a ‘gaping hole’ in a widely used method for evaluating software security. Hiep patched the hole, causing quite a stir in his field. 'It’s not pleasant when a PhD…

The biographer of Leiden University, Willem Otterspeer, has a new book out. In ‘De stad, de dood en de dichters’ (The City, Death and the Poets) he combines his love for the University and poetry with autobiographical reflections. ‘With my magnifying glass I discovered yet more new details in the pr…

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that structure DNA. Now, Leiden PhD candidate Samuel Schwab has found that the histones in these organisms are much more diverse than previously thought. Schwab and his colleagues describe…

An international team of astronomers led by Dutch scientist Martijn Oei has discovered the largest pair of jets from a black hole ever seen. The 'jumbojets' extend a combined length of 140 Milky Ways. The Leiden Observatory played a prominent role in this research. The publication will feature on the…

While tens of thousands of visitors dance to deafening music, a team of Leiden psychologists are trying to collect data for their research at Lowlands. How do festivalgoers experience a virtual trip? And what role do factors such as too little sleep and whether they have experience with psychedelics…

How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…

Earning some quick money by drug trafficking, committing an act of violence or almost collapsing under performance pressure. In the four-part NeurolabNL Young vodcast young people talk openly with neuroscientists about high-risk behaviour and performance pressure. How did they find their way back?

Erik Danen is the new Dean of the Graduate School from 1 January. He is a professor at the Leiden Academic Centre for Drug Research and conducts research into cancer drugs. Danen is really looking forward to it: ‘PhD candidates are a special group: that's what I like to dedicate myself to.’

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

Armed with sunglasses, a thick layer of sunscreen and several bottles of water, over 3,300 students have arrived in Leiden for their introduction week. The start of the 55th EL CID happened to be on the hottest day of the year.

How can parents avoid passing on stress and mental health problems to their children? Professor of Stress-Related Psychopathology Bernet Elzinga develops simple interventions to help both parents and young people. For her research, she has been awarded the Spinoza Prize, the highest academic honour…

Op zaterdag 3 juni vindt de Museumnacht Leiden plaats. Ook dit jaar zijn Leidse wetenschappers en studenten onderdeel van de programmering.

It will be a summer filled with conferences at the Faculty of Humanities in Leiden. In the coming months, there will be something for everyone at the university, especially in the field of languages and cultures of Africa and the Middle East.

A team of scientists, including Leiden Astronomer Alice Booth, has discovered silicon monosulfide molecules in the dust disk around a young star. Such molecules indicate planet formation. The team made the discovery using the ALMA telescopes. This method provides an alternative when direct observation…

EuroScience Open Forum – ESOF - is Europe’s biggest multidisciplinary and prestigious scientific conference. ESOF2022 will take place from 13-16 July 2022 and is hosted by Leiden as the European City of Science (in the Netherlands). The Kamerlingh Onnes Building is one of the locations of the ESOF and…