Can epigenetic changes explain associations between early life stress and health outcomes?

In the CSM-elective ‘Governance of Crime and Social Disorder,’ Dr. Elke Devroe challenges her students to engage in an interactive group role-play on various themes related to the governance of crime. During this exercise, each group of students brings to life a sensitive security topic – such as mass…

Electronic versions of our publications can be obtained by sending an e-mail to Esther van den Bos: bosejvanden@fsw.leidenuniv.nl

Livia, aged 7, was in class four. She loved to chat and was good at reading aloud. At least, at home. At school she never read aloud and she hadn't spoken a single word. What was going on? Selective mutism was the subject of the inaugural lecture by Maretha de Jonge, Professor by Special Appointment…

How are people of color represented in art collections? And do young people of color feel that museum collections reflect their norms and values? Developmental psychologist Carolien Rieffe is invited to serve on the Expert Group ‘Musea bekennen kleur’ because of her knowledge of children and young p…

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

Teacher Dr. Elke Devroe introduces group role-play on actual themes of governance of crime and social disorder. Seven groups of 5 students each presented last Tuesday March 17th pro’s and con’s of the topic of their choice in a panel in a TV-show setting. Students enjoyed lifting green and red cards…

Promotor: Prof.dr. C.W.J. Beenakker

On June 9-10 2016 Dr. E. Devroe of the Institute of Security and Global Affairs (ISGA) was invited as a key-note speaker on ‘Intelligence Led policing and community oriented policing’ at the annual meeting of the ‘Organization for Security and Co-operation in Europe’ (OSCE), Transnational Threats Department,…

The objective of the Next Generation ImmunoDermatology project (funding NWO, program NWA-ORC) is to deep profile the immune-mediated inflammatory diseases: i) atopic dermatitis (AD), ii) cutaneous lupus erythematosus (CLE) iii) chronic spontaneous urticaria (CSU) iv) hidradenitis suppurativa (HS) v)…

Speech Prosody 2024 includes several poster sessions, the description of which you can find below.

Lecture

Optimization, mechanisms of action and predictors of the outcome of light therapy in depression: A multicenter randomized trial

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

Health is a wonderful gift, both for humans and for society. If we are able to prevent both physical and mental illnesses, we can spare a lot of suffering and fight rising health costs. Social scientists and physicians in Leiden are working closely together to conduct research on the human mental, behavioural…

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

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Together with researchers from over the world, the ENIGMA-Anxiety Working Group endeavors to unravel the neurobiology of anxiety disorders and related constructs.

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.

The aim of our research program is to better understand the etiology and course of mood, anxiety and stress-related disorders, such as depression and posttraumatic stress disorder (PTSD). We investigate both the transdiagnostic mechanisms underlying these disorders and work on improving the treatments…

Are disturbances to the brain, such as Alzheimer's or autism, linked to specific defects in the underlying communication networks in the brain? If this is the case, subtle changes in the networks can act as a marker for brain disturbances. Neuroscientist Serge Rombouts will be investigating this, together…

In this project we followed children of parents with an anxiety disorder. We wanted to examine how these children develop and try to better understand why it is that some children develop fears, whilst other children do not. In this project, we mainly focus on social anxiety disorder and panic disor…

What are the developmental pathways to social anxiety (disorder), the causal processes and maintaining factors? How do these factors interact in the development of social anxiety disorder? How can this knowledge be used to design and implement effective preventive intervention programs for youth?

People already diagnosed with a mental disorder before the COVID-19 pandemic did not show a disproportionate increase in symptoms afterwards. This is one result from the first systematic review of longitudinal studies following their study population from before to during the first eighteen months of…

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

The Leiden Institute for Brain and Cognition (LIBC) is a network that stimulates interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition and focuses on science valorisation and outreach.

On 9 November, Roosmarijn van Es defended the thesis 'The mind in the courtroom: on forensic mental health reports in judicial decision-making about guilt and sentencing in the Netherlands. The doctoral research was supervised by Jan de Keijser, Maarten Kunst and Janne van Doorn.

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

ADHD & ME aims to explore how enhancing self-esteem can break the relation between ADHD symptoms and comorbid disorders, such as anxiety and depression. In this study we assess the effectiveness of a Cognitive Behavioural Therapy (CBT) program called Competitive Memory Training (COMET) for improving…

The overarching aim of this theme is to increase our understanding of the mechanisms underlying altered cognitive, affective, and social behavior in relation to mental health problems.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher