140 search results for “protein” in the Staff website
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Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
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How cool is LEGO®? Leiden physicists use it for ice cold research
Tjerk Oosterkamp's group is conducting what is perhaps the coldest research in the world. The researchers have cooled a sensor to below 2 millikelvin - almost as cold as absolute zero. This allows them to make extremely sensitive measurements. PhD candidate Jaimy Plugge helped build the setup: ‘We are…
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Jasper's day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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Virtual preparation for lab practicals
How can we better prepare students for their practicals, so that they learn more from them? Marjo de Graauw and her colleagues want to renew science education. Together they will develop interactive teaching materials to introduce students to laboratory courses. They are receiving a SURF grant of €100,000…
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How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
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Functions and biosynthesis of a tip-associated glycan in Streptomyces
PhD defence
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SAILS Lunch Time Seminar
Lecture
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Ruthenium- and cobalt-based artificial metalloenzymes for photocatalytic water oxidation in artificial photosynthesis
PhD defence
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Learning Unkown Intervention Targets in Structural Causal Models
Lecture
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Regulation of autophagy-related mechanisms during bacterial infection
PhD defence
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Thiosugars: Reactivity, methodology and applications
PhD defence
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Using cryo-EM methods to uncover structure and function of bacteriophages
PhD defence
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New technology could prevent the mass cull of male chicks
A staggering 6.5 billion chicks are killed worldwide every year. These are generally male chicks that are of no economic value. In Ovo has developed technology that can quickly determine the sex of a chick, to ensure that only female chicks are hatched. The first 150,000 chicks have now hatched in this…
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How animals flirt with each other
How do animals choose their partners? The answer is simple: it’s all about quality. While humans tend to wear clothes that happen to be in fashion, animals do nothing without a reason. Behind beautiful plumage or a deafening roar is only one message: I am in great shape. The evolutionary courtship displays…
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Jasper's Day
On January 1st Jasper Knoester started as our new dean. How is he finding it? What kinds of things is he doing and what does his day look like? In each newsletter, Jasper gives a peek into his life as dean.
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Physics in the picture: cancer cells as an explosion of fireworks
When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…
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Medical Delta professor Marcel Reinders: ‘You need collaboration to make a real impact’
Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…
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Hoe meer tijd, hoe beter de nier
Donororganen zijn er nooit genoeg. De organen die wel beschikbaar zijn, moeten vliegensvlug getransplanteerd worden. De geneeskunde zet daarom volop in op het langer goedhouden van organen. Marlon de Haan (24) onderzoekt hoe je nieren buiten het lichaam in leven kunt houden.
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New research reveals link between finger tapping and Alzheimer's
Suddenly getting lost, failing to recognise family members, or forgetting words and names are well-known symptoms of Alzheimer's disease. Psychologists have now discovered that the disease also manifests in more subtle ways: through the rhythm of finger tapping.
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Seven Leiden professors elected new members of KNAW
Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.
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New education director for LST: 'I want to guard the quality of this unique programme'
Marco van Eijk is the new Educational Director of the Bachelor's Life Science and Technology (LST). Since 1 September he has been responsible for ensuring the quality of the programme. ‘LST is a unique programme and everyone has to keep working hard for that. That is my main task.’
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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Stiffness and viscosity of cells differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.
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Computational Biology Modeling with Tree Search and Learning
Lecture
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Optoplasmonic Detection of Single Particles and Molecules in Motion
PhD defence
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Joan van der Waals colloquium by Daniela Wilson
Lecture
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How the eating habits of a limited group of Americans determine sustainability
Masses of hamburgers, steaks, cheese and a lot of eggs: Americans love their animal products. But researcher Oliver Taherzadeh discovered that only a relatively small group of high-volume consumers need to modify their diet to achieve an enormous environmental gain.
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Key for effective application of a new revolutionary cholesterol lowering drug resides in a 30 year old Leiden Patent
‘’ And then the world changed forever ,welcome to the future’’. These are the words that Kausik Ray (President of the European Atherosclerosis Society) spoke when the worldwide first dose of inclisiran, a novel SiRNA based cholesterol lowering agent, was administered at the Cardiology lipid clinic at…
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The future of the past is enough to make you feel down
The slogan of the Faculty of Archaeology, ‘The Future of the Past starts at Leiden University’, might sound like empty marketing speak. But there is something to it. The past can teach us a lot about climate change and that could make us fear the worst for our future. Archaeologist Gerrit Dusseldorp…
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Bioengineering and Biophysics of Viral Hemorrhagic Fever
PhD defence
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Evolutionary adaptability of β-lactamase
PhD defence
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
PhD defence
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SAILS Lunch Time Seminar
Lecture
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
PhD defence
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How to develop cancer drugs with less side effects
Lecture, Tuesday Talks: Science Insights
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Career Talk with Maurien Olsthoorn
Debate, Career Talk
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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Alumna Sytske Besemer on living and working abroad
This month's flash interview is with alumna Sytske Besemer, Criminologist, who works at a startup called Cradle. Sytske has specifically chosen to work for a company with societal impact. And she is about to move again, this time to Zürich.
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LIC Lecture + drinks
Lecture