LUMC Technology Focus Area (TFA) Data Analytics is een samenwerkingsverband van verschillende onderzoeksgroepen in het LUMC die nieuwe kwantitatieve en computationele methodologie ontwikkelen voor biomedisch en klinisch onderzoek.

The master’s specialisation Biology and Science Communication and Society at Leiden University bridges the gap between experts and the public by combining high quality research in biology with extensive training in science communication.

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

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Mission: The Environmental Biology department aims to increase the scientific understanding of how current and emerging anthropogenic threats affect biodiversity and ecosystem services. Through this understanding they facilitate strategic management of natural resources by addressing urgent challenges…

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

A theoretical project on the insights gained by human (including infant), nonhuman animal and computational studies on artificial grammar learning; identifying the critical questions for future research by developing novel experimental and computational approaches to address these issues.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

ISBA2025

MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.

Can cyclic peptides provide a new generation of antibiotics?

Overkleeft

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.

We study cell-fate decision-making using embryonic stem cells as a model system. Stem cells integrate a large number of cues to direct their development into a great variety of cell types.

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

FAIRDOM consortium is an open initiative of various partners including funding programmes, large-consortia, institutes, small groups as well as individuals.

Is it possible for sugar patterns on cells to activate the immune system to combat cancer?

Stay tuned for updates on relevant media appearances of Marieke Liem.

A juvenile suspect has been apprehended for the murder of 15-year old Megan from Breda last Monday. A highly unusual situation, according to Marieke Liem, Associate Professor at the Institute of Security and Global Affairs in The Hague. She gave an interview to Dutch newspaper AD.

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

Promotores: H.A. Udo De Haes, P.M. Brakefield

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

On Wednesday 26 June, Marieke Liem, Associate Professor Physical Violence and Public Order at Leiden University’s Institute of Security and Global Affairs (ISGA), appeared on both Dutch radio programme ‘Nieuws & CO’ and the eight o’clock television news (NOS) to discuss life imprisonment.

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

Anthropologist Marieke Slootman received the NSV Dissertation Prize 2015 for her dissertation on ethnic identification among Moroccan and Turkish Dutch.

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

Lex Bohlmeijer, creator of the Good Conversations podcast at De Correspondent, is recording a podcast in Theater aan het Spui in The Hague. In his Good Coversations podcast, Lex talks politics, arts, journalism and science, with a wide range of guests who have an exceptional and often unknown story.…

Every year Leiden University celebrates the lifting of the siege of 1574, with the 3 October University. This year the event will be held on the 4th of October between 11 am and 1 pm. Visit the tent in the city centre of Leiden, to hear three of our scientists talk about their research on the theme…

As a humanities researcher, it is not always easy to explain to other people why what you do is important. It is easy for people to see why searching a cure for cancer matters, but it is a bit harder to make clear why it is also important to study language, culture, and history. One of the things that…

We will study how inoculation of former arable land with soil (including the microbiome, soil fauna and seeds/rhizomes of ground flora) from old forests along with planting targeted tree species mixtures will improve productivity and more rapidly restore forest-adapted communities and ulttimately result…

What does it mean to be in a Dutch prison? What is true about the prejudices about being in jail? Criminologist Marieke Liem has released a podcast on Dutch national broadcaster NPO Radio 1: Hotel met tralies.

Marieke Liem is an Associate Professor at the Institute for Security and Global Affairs of Leiden University in The Hague. She was interviewed by local Leiden radio programme ‘Sleutelstad’ about her research into murder cases in the Netherlands.