Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: Prof.dr. B. van de Water, Co-promotores: J.W. van der Laan, C.L.E. Siezen

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

Cellular stress response pathways are activated upon exposure to chemicals and help organisms deal with various molecular dangers (e.g. oxidative stress). When these pathways become hyper-activated an adverse response takes place and cells die, which may lead to organism-level toxicity such as drug-induced…

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

The overall aim of CAM-PaC is to contribute to solving the socioeconomic and health challenges of PDAC by an integrative and systematic functional analysis of pancreatic cancer candidate genes. CAM-PaC will develop novel cellular and animal models, as well as novel strategies to analyse and integrate…

The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.

Study information, Online Experience

On 21 March 2024, the ‘learners’ at Wolfert Bilingual in Rotterdam were not teenagers, but some 180 teachers and teacher educators from around the Netherlands and beyond. Those delegates were bound by a common interest in exploring and engaging with teaching and learning in linguistically and culturally…

Three quantum-safe cryptography methods have been standardised for worldwide use since this week. Léo Ducas co-designed the two primary PQC methods selected for this standardisation. Ducas is part of the Cryptology group at Centrum Wiskunde & Informatica (CWI) and is also professor of Mathematical cryptology…

Annetje Ottow, president of the Executive Board of Leiden University, has been the new chair of the Leiden-Delft-Erasmus (LDE) strategic alliance for just two months. What does she want to achieve during her two-year chairmanship?

On 8 October, the Independent Expert, Prof. Manfred Nowak, leading the UN Global Study on Children Deprived of Liberty presented his report to the UN General Assembly. The presentation of the final report is set for 19 November 2019, at the occasion of the 30th anniversary of the UN Convention on the…

An organized overview of the current global fungal diversity, that is what Irene Martorelli and colleagues try to achieve with the new MycoDiversity Database (MDDB) she builds in collaboration with Naturalis Biodiversity Center. The new database will make it easier and quicker to observe which fungi…

Study information, Webinar

PhD defence

The Dutch and English East India Companies were formidable organizations that were gifted with expansive powers that allowed them to conduct diplomacy, wage war and seize territorial possessions. But they did not move into an empty arena in which they were free to deploy these powers without resista…

The Role and Effectiveness of the G20. In this article, published in The Changing Global Order part of the United Nations University Series on Regionalism book series, author Jaroslaw Kantorowicz discusses the evolution of the G20.

Eve Darian-Smith and Phil McCarty presented their book 'The Global Turn Theories, Research Designs, and Methods for Global Studies' during a book presentation seminar.

The challenges of building a sustainable society are unprecedented. But the Dutch municipalities cannot be faulted for their commitment. They are working hard, conclude Professor Eefje Cuppen and Lian Merkx, programme manager for energy at the Association of Netherlands Municipalities (VNG). To exchange…

Science diplomacy, broadly defined as all activities at the intersection of science and foreign policy, has become a buzzword during the past ten years.

On 19 April, CML researcher Nadia Soudzilovskaia gave an invited talk at The Global Biodiversity Information Facility (GBIF) about her VIDI-funded work on impacts of mycorrhizas on ecosystem functioning. During this project she will closely collaborate with GBIF colleagues.

Together with College of Europe Professors Sieglinde Gstöhl and Simon Schunz, Joris Larik edited an interdisciplinary special issue for the Journal of European Integration on the theme 'The European Union and the Governance of Contested Global Spaces in an Era of Geopolitics'.

On 27-29 June, 2023, Leiden University's Institute for History will host a summer school on Global History in the 2020s, in collaboration with the Huizinga Institute-Research School for Cultural History, the Research School Political History, and the Flying University of Transnational Humanities (FUTH).…

On Thursday 8 September, the Hague newspaper 'Den Haag Centraal' issued a special annex dedicated to the Faculty of Governance and Global Affairs.

Since 1919 the International Labour Organization (ILO) has been promoting the rights of workers worldwide. On 7 February, Leiden University hosted the symposium celebrating the 100-year anniversary of the foundation of the ILO. Leiden emeritus professor of International Labour Law Paul van der Heijden…

Although seen as the fastest and cheapest way to global climate protection, a uniform global carbon price would have major consequences for the economic competitiveness of countries. Hauke Ward, who recently joined Leiden University, showed in the journal Energy Economics that modern western countries…

A wide range of metals need to be mined for solar panels, wind turbines and batteries. But the overall mining activity is set to decrease as clean energy replaces fossil fuels such as oil, coal and gas.

Jeanine de Roy van Zuijdewijn was invited to give the subject matter expert speech during the plenary meeting of the working groups of the Global Coalition against Daesh in Copenhagen on 28 January 2020.

The Summer School ‘The European Union, the United Nations and Global Governance’ is open to Master-level and PhD students. It is supported by the European Union’s Jean Monnet program.

The Summer School will take place from 14-25 June 2021 and welcomes Master-level and PhD-level students who are interested in learning more about the interactions between the EU and the UN and the EU’s role within current patterns in global governance.

Study information, On Campus Experience

From 15-19 July 2019, the department of Labour Law hosted the first Global & European Labour Law Summer School. Participants from 10 different nationalities and 3 different continents joined the Summer School.

The Centre for Global Heritage and Development has been successful in applying for a MOOC (Massive Open Online Course) on the topic of threatened heritage at ICTO, the platform for innovation and education at Leiden University.

Simon Willmetts walks listeners through the founding of the CIA, its successes, controversies, portrayal in media and film.

The Leiden University Fund (LUF) awards grants to research and educational project in various academic fields once a year. This year, Andrei Poama, Jochem Jansen, Valérie Pattyn and Min Cho of the Faculty of Governance and Global Affairs were four of the recipients of such a grant.

On 8 December, Friday afternoon, the second year students of the Honours College track ‘Tackling Global Challenges’ presented their final assignment for the Competences Lab course. The goal was to set up an impact project and organize an event about it. The diverse groups listened and shared their ideas…

On 26-28 June, 2023, Leiden University’s Institute for History will host a summer school on Socioeconomic diplomacy and global empire building, 16th-19th centuries, in collaboration with the N.W. Posthumus Institute (the research school for economic and social history in the Netherlands and Flanders)…

Online teaching has made it much easier for international students to join in our courses. The Leiden minor in Global Health, for instance. Students from Tanzania, Rwanda, Uganda and Malawi logged on and made a valuable contribution with their knowledge, about tropical diseases, for instance.

The monthly ILS Lunch Seminars have slowly developed into somewhat of a tradition. During this seminar series, all researchers from Leiden Law School can present their research and apprehend in a comfortable setting what researchers from other research programs and institutes are working on.

On 15 July 2019 Hans-Martien ten Napel started a new series on freedom of religion or belief for the London School of Economics research-led interdisciplinary Religion and Global Society Blog.

The article deals with an issue that will be at the heart of the World Health Assembly to be held in May, namely the concept of ‘deep prevention’ and the importance of its integration in the Global Pandemic Treaty - which has been recently proposed by the European Council and currently endorsed by more…

As a member of the international advisory board, Prof. Dr. Ton Liefaard, participated in the final expert meeting of the United Nations Global Study on Children Deprived of Liberty, in Venice from 11-13 March 2019.

Researchers from the Leiden University Medical Center (LUMC) are working on the first diagnostic test for leprosy that can be used outside a laboratory. This will not only reliably diagnose leprosy, but also be cheap and easy to use. Leprosy mainly occurs in low-income countries. A double challenge…

Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.

The Centro de Estudos Internacionais at Instituto Universitário de Lisboa (ISCTE-IUL) will host the

The protection of civilians (POC) in armed conflict has become a core strategic objective for the United Nations system and for UN peace operations in particular. The UN, however, is not the sole actor engaged in POC.