Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Valedictory lecture

Leiden University has appointed John van Noort as Professor in Biophysics. He studies the way in which our DNA is folded and read out.

Vera van Noort has been appointed Professor in the field of Computational Biology within the Faculty of Science at the Institute of Biology from the 1st of February 2017. Van Noort’s expertise is in bioinformatics and her research focuses on the computational analysis of large-scale biological data…

Vera van Noort, professor in Computational Systems Biology at the KU Leuven (Belgium), is appointed holder of the rotating chair “Van der Klaauw Professor” for the year 2015-2016 at the Institute of Biology. Holders of the chair bring inspiring research and teaching in theoretical biology to the University.…

On 30 October 2020, Dr Mark Noort successfully defended his PhD investigation at the London School of Economics and political science (LSE) into

Met de benoeming van Rijpma en Campos Delgado is de Faculteit der Rechtsgeleerdheid in alle uniersitaire regiogroepen vertegenwoordigd.

Jelle van Buuren, university lecturer at ISGA, discusses the role that social media played in the storming of the Capitol last Wednesday

Relevant publications of the CIGR participants.

eLaw- Center for Law and Digital Technologies is based in the Kamerlingh Onnes Building, Steenschuur 25, 2311 ES Leiden.

John van Noort

The portfolio of eLaw includes research executed for the European Commission, NWO (the national research council in the Netherlands), the national government, local government agencies, large corporations, SMEs and NGOs.

The academic staff of the Leiden University Institute for History.

Promotor: Prof.dr. E.F. Smets, Co-promotor: Dr. V.S.F.T. Merckx

Visualization of biomolecules in living cells by tagging with gold nanoparticles.

How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?

Promotor: Prof.dr. T. Schmidt, Co-promotor: Dr. ir. S. J.T. van Noort

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

Key research articles and book chapters of the Chromatin group.

An overview of awards and prizes granted to our staff and students in 2017, as well as special appointments and royal distinctions.

Science, Leiden Institute of Physics (LION)

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

“Het is niet genoeg dat Amerika aanwezig is in de ruimte. Amerika moet domineren”, zegt Donald Trump tijdens een bijeenkomst met de Nationale Ruimteraad. Zodoende wil hij naast de land-, zee-, en luchtmacht een nieuwe militaire kracht oprichten: de Space Force. Ruimterecht deskundige Tanja Masson denkt…

Genes are active sometimes, and other times they remain dormant for a while. Leiden physicist John van Noort receives an NWO ECHO grant to find out how this happens.

Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…

What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?

The way DNA folds, largely determines which genes are read out. John van Noort and his group have quantified how easily rolled-up DNA parts stack. This costs less energy than previously assumed. Publication in Biophysical Journal.

In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…

Leiden physicists are helping Wageningen plant researchers to study unpredictable plant embryos. For this, they are using a novel two-photon fluorescence microscope, aided by a 30 thousand euro ZonMW grant.

Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.

The way genes are folded determines their activity in our body. Leiden biophysicists are now the first to unravel this structure molecule-by-molecule. Publication on December 1st in Nature’s Scientific Reports.

From underground heat exchangers at the Bio Science Park to drinking taps to replace water coolers. With its new environmental policy plan, Leiden University will become greener in the coming years.

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

Human Rights organisation Amnesty International recently set up a walk that passes by important locations in Leiden in relation to human rights. The Kamerlingh Onnes Building, home to Leiden Law School, has been included in the route.

Following China and Italy, it appears that the United States is becoming the next epicentre of the coronacrisis. Can the US handle this crisis? Is president Trump dealing with the situation correctly? We asked Leiden America expert Sara Polak.

Researchers Wim van Noort, Sandra Groeneveld, Marieke van der Hoek, Jelmer Schalk en Joris van der Voet published a book on public organizations.

The project has been done in the Organization and Dynamic Chromatin group under the supervision of Prof. dr.ir. S.J.T. van Noort. The title of the presentation is: ''Structural changes induced by variation of linker DNA length.

The project has been done in the Biological Matter group under the supervision of Prof. dr. ir. S.J.T. van Noort and Prof. dr. M.A.G.J. Orrit.The title of the presentation is: ''Characterization of Single Gold Nanorods with Two Photon Microscopy.

The project has been done in the Biological Matter group under the supervision of Dr.ir. John van Noort. The title of the presentation is: ''G-Quadruplex structure in double-stranded DNA studied by a combination of FRET and Magnetic Tweezers.

Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?

We encourage applications of visiting scholars whose research interests and activities are in line with our research programme 'Effective Protection of Fundamental Rights in a Pluralist World' or our Key Research Themes. Our dynamic, multidisciplinary research programme aims to bring together researchers…

The 'Intelligent Lockdown' has lasted over a month now, which makes experimental physics research hard to do, if not downright impossible. Even so, work is continuing. Five Leiden physicists tell us about it.