One and half years ago, Lewis Borck exchanged the arid and hot Southwest of the USA for the Netherlands. While an expert in Ancestral Pueblo and Hohokam archaeology, he switched to the Caribbean as a researcher in the NEXUS 1492 project. “Theories and methods brought me in first.”

A semi-empirical version of the specific reaction parameter approach to density functional theory (SRP-DFT) has been remarkably successful at predicting dissociative chemisorption probability vs. incidence energy curves for reactions on metal surfaces. New quantum Monte Carlo (QMC) calculations on the…

This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…

This subproject of 'From Homo Economicus to Political Animal' will be on ancient analogues for modern-day “ersatz economics”, the economics of the “man in the street”.

Elise Darras studeert aan het Leiden University College (LUC) en be besloot een maand lang stage te lopen in Frankrijk bij H2Air.

During last summer, the Faculty of Law offered an Honours Class about the theme 'Governing Crime and Migration'. Hillary Mellinger, one of the participating international students, tells us about her experiences.

How public service motivation and professionalism affect decision-making in dilemma situations. Individuals who work in the public sector see themselves confronted with conflicting values, contradictory demands, and the need to serve an at times difficult to define ‘public interest’.

In his dissertation Gabriel Paiuk explores the variable ways in which what is heard is formed. To address this, he postulates a novel concept of sound image in a post-anthropocentric context in which both mind and material artefacts are instances across which the image occurs, rather than hosts on which…

PhD defence

Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)

Promotor: Prof.dr. P. Stevenhagen & Prof.dr. K. Belabas (Univ. de Bordeaux)

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

This subproject of 'From Homo Economicus to Political Animal' analyzes Greek economic thinking in late 5th- and 4th-century philosophical circles.

In the spirit of 'unity in diversity', our objective is to promote insight into and appreciation for the wonder that the same physical laws and mathematical concepts apply to the whole of nature, from the largest to the smallest energy and length scales. We strive for the application of abstract theoretical…

Leiden chemists have proposed a new model for enzymatic reactions, in which the flexibility of the substrate is much more important than previously thought. Their results are paradigm-shifting and could have major implications for drug research and enzyme engineering. Publication in Angewandte Chemi…

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.

This research group, headed by Miranda van Eck, focusses on understanding the molecular mechanisms underlying cardiovascular and metabolic diseases. Cardiovascular disease constitutes a major health issue worldwide. Although significant knowledge has been obtained on the development of atherosclerotic…

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

The research master's specialisation Developmental Psychology consists of five main parts: the general courses, the specialisation-specific courses, the elective courses, a research internship and a thesis.

PhD defence

PhD defence

PhD defence

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Connecting Agriculture, Crafts, Construction, Transport, and Resilience Strategies

Promotores: J.C. van Houwelingen, S.A. van de Geer

Effects of maternal smoking, premature birth, intra-uterine growth retardation and asphyxia on child development.

We aim to develop A. niger strains that produce more starch degrading enzymes even in the absence of starch.

The Institute of Biology Leiden (IBL) is an internationally oriented institute for research and education in biology. We are part of the Faculty of Science at Leiden University.

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: Dr. A. El Ghalbzouri

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros