How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

Various companies in the plant biotech industry will test a recent Leiden discovery in their crops. The ‘Pol Theta’ technology is developed in Leiden and makes it possible to reduce undesired side effects during genome engineering of plants.

Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…

At the division of BioTherapeutics, Amanda Foks, Bram Slütter and Ilze Bot have obtained a €4 million research grant from the HORIZON 2022 EIC Pathfinder Challenge “Cardiogenomics”, entitled “B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVD”.

Uncovering ageing processes in the brain and research on the use of the word ‘that’. Thanks to a Rubicon Grant, two Leiden researchers who were recently awarded their PhDs will be able to conduct research at a research institute abroad.

Why do opposites attract? According to Karin van der Tuin, researcher at Leiden University Medical Center (LUMC), it could be because of your DNA. The more you differ from one another, the better. She will be testing her ideas at the Lowlands festival Lowlands, where she will subject visitors to DNA…

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…

Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.

By analysing the metabolism using big data techniques, we can identify health risks at an earlier stage. Thomas Hankemeier, professor of Analytical Biosciences at the Leiden Academic Centre for Drug Research, explains how that works.

Edith Schippers, Minister of Health, will be investing six million euros over the coming four years to boost research on new antibiotics. The programme will be set up by several different parties, including the Leiden Centre for Antimicrobial Research.

NWO has awarded a Vidi subsidy to a total of 89 young and innovative researchers. Leiden researchers have won twelve of these subsidies and three subsidies have gone to the LUMC. Each researcher will receive up to 800,000 euro to develop a particular research theme or to set up a research group.

The brain structure of young people with conduct disorder differs significantly from that of their typically developing peers. This is the conclusion of an international study that analysed more than two thousand MRI scans, recently published in The Lancet Psychiatry. Dr Moji Aghajani, one of the principal…

Mathematician Stéphanie van der Pas, winner of the C.J. Kok Jury Award for her PhD thesis in 2017, divides her time between research and education, and between pure mathematics and practical application.

A Memorandum of Understanding was signed by Professor Corinne Hofman of the Faculty of Archaeology, Leiden University and Professor Albert Feilzer from the Academic Centre for Dentistry (ACTA), University of Amsterdam and VU University, Amsterdam.

Ben Wielstra and his team have received a ENW-M-1 grant. This grant of 354.000 euros is awarded by NWO, and will enable the researchers of the Institute of Biology Leiden and Naturalis to continue their evolutionary newt research.

Theoretical physicist Helmut Schiessel receives an NWO Projectruimte grant of 390,000 euro. He will use this budget to hire a postdoc and a PhD student to continue his research on flexibility of double stranded DNA.

Freek Vonk and Mike Richardson, with many collaborators, have published two snake genomes in two parallel articles in the prestigious journal PNAS. Their new findings provide insight into the co-evolutionary arms race between predator and prey.

The past decade, against the backdrop of a fragmented political landscape, has witnessed the greatest changes to the Netherlands since the aftermath of the Second World War. The labour market, the housing market, the energy market, the bank system, the pension system, the healthcare system, to name…

The Open Day of Leiden University, on the 8th of this month, was a success again: 483 prospective students came to find out what Leiden has to offer. The Institute of Biology Leiden was also present.

Leiden University is involved in five new NWO Gravitation projects. Two relate to mental disorder and the remaining three to a healthy lifestyle, the combination of human and artificial intelligence, and the special relationship between plants and microbes.

Paco Barona Gomez is the newest associate professor at the Institute of Biology Leiden (IBL). The Mexican researcher is fascinated by the evolution of natural products: compounds made by microbes, but also plants and animals. ‘It’s like we investigate chemical dark matter.’

Researchers, policymakers and funders have to take more account of the effect of sex and gender in scientific research. This is the view presented in an advice paper published by LERU, the League of European Research Universities. The lead author is Vice-Rector Simone Buitendijk.

Nine talented Leiden researchers have been awarded a Vidi subsidy by the Netherlands Organisation for Scientific Research (NWO). Vidis are intended for researchers with several years of research experience who want to set up or expand their own line of research.

The Dutch National Research Agenda announced today that it will provide 17 research projects with a total of 61 million euros in funding. Researchers from Leiden University or the Leiden University Medical Center are involved in five of the projects. All of the projects are interdisciplinary partnerships…

To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

A new 5.7 million euro research project will ensure that lettuce will be more resistant to pathogens and climate effects and will grow better in new cultivation systems. Together with other Dutch researchers, Leiden biologists will map the characteristics and genetic information of 500 wild and cultivated…

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

Hardly anyone in the Netherlands ever watches skeleton racing. But we’ll soon be glued to our TV sets when ‘our’ Kimberley Bos slides down the track at the Olympic Games. All because she stands a good chance of winning a medal. Why do we like winners so much?

On March 21 2018, a study was published in Nature, co-authored by Professor M. Soressi from the Faculty of Archaeology of Leiden University, announcing the sequencing of five new Neandertals, raising the number of high-coverage sequenced Neandertals from two to seven. A tooth lost by a Neandertal woman…

The first Eugene Garfield Award for Innovation In Citation Analysis has been granted to Jian Wang, Assistant Professor in the Science Based Business Program at Leiden University.

LUMC and Leiden University will start the new two-year online master's program in Transfusion Medicine and Cellular and Tissue Therapies from October 2023.

Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).

Publication by: Vanessa Frodermann, Janine van Duijn, Gijs van Puijvelde, Peter van Santbrink, Max Lagraauw, Margreet de Vries, Paul Quax, Ilze Bot, Amanda Foks, Saskia de Jager and Johan Kuiper. Journal of Internal Medicine. 2016;279:592-605.

The Lowlands pop festival is inviting scientists to make proposals for research at this year's festival (19 to 21 August).

On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.

In April, the X-omics initiative was granted 17 million euros from the Dutch Organization for Scientific Research. The subsidy is part of the National Roadmap for large-scale scientific infrastructure, intended to build or renew large-scale research facilities. What new insights will this investment…

For her research on social-emotional regulation in children Michelle Achterberg on Wednesday, May 25 2022 received the Dutch Association of Developmental Psychology (VNOP) Dissertation Prize. With her PhD research, she mapped out which mechanisms play a role in social emotion regulation in childhood.…

Leiden physicist Maarten Kruithof has discovered how our DNA is infallibly able to fold itself and to unfold again. In his dissertation he demonstrates how DNA is folded in a single long, very flexible spiral.

This year's Nobel Prize for Medicine goes to the three American researchers who have unravelled the mechanism behind the biological clock. Joke Meijer, Professor of Neurophysiology and an expert in the field of the sleep-wake rhythm, explained in Dutch newspapers Trouw and NRC why this discovery is…

Four Leiden researchers will be gaining experience at prominent international research research institutes funded by a Rubicon subsidy from NWO. One international researcher will be coming to Leiden.

Joris van der Voet’s article “Organizational Decline and Innovation in Public Organizations: A Contextual Framework of Cutback Management” won the 2019 Camilla Stivers Award for best article in Perspectives on Public Management and Governance.

Members of our research team give different types of presentations and lectures.

Leiden scientists are the main applicants for five projects that have been awarded a Science Groot grant of up to 3 million euros in the Science Domain. In addition, several Leiden scientists are involved in other projects that have been awarded funding.

Data and information should be stored in a way that computers can understand, says Barend Mons, professor of Biosemantics at the Leiden University Medical Center and Chair of the High Level Expert Group for the European Open Science Cloud. We speak with him about FAIR data, knowlets and nanopublicat…

This year, NWO has awarded a Veni subsidy to 143 young researchers who have recently obtained their PhD. 17 of these researchers are at Leiden University and one works at the LUMC. The successful applicants will each receive 250,000 euro to develop their ideas and carry out research over a period of…