4,015 search results for “discovery of the year” in the Public website
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Unravelling the genes responsible for life history traits in the giant woody cabbage (Brassica oleracea)
Which genes are involved in woodiness and associated traits such as drought tolerance, flowering time, stem elongation, life span, and plant herbivory, and how do these gene regulatory pathways overlap?
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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The molecular secrets of medicinal cannabis
Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…
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Opening Museum and research center Paläon
One of the highlights during the fieldwork in Schoningen lead by Prof. dr. Thijs van Kolfschoten in 2013 was the opening of the museum and research center paläon on June 24. To the realisation of the museum, the Faculty of Archaeology made a significant contribution. Many of the results of the research…
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Scientists discover how to improve the production of antibiotics and enzymes in soil bacteria
A team of researchers at the Institute of Biology Leiden, in collaboration with scientists from Utrecht University, has discovered a novel approach to improve the production of antibiotics and enzymes in the soil bacteria Streptomycetes.
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The Internationalisation of the Labour Question: Ideological Antagonism, Workers’ Movements and the ILO since 1919
This book connects labour history, global history and the institutional or political history of international organisations.
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Better ligands for G Protein-Coupled Receptors
The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.
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Freon-40 may not be a useful marker of life
Observations made with the ALMA telescope in Chile and ESA’s Rosetta mission, have detected the faint molecular fingerprint of methyl chloride in gas, a chemical commonly produced by industrial biological processes on Earth, around both an infant star and a comet. Methyl chloride, also known as Freon-40,…
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The Extension of the Historical GIS Friesland
In this project the already developed parcel based historical GIS (HISGIS) for the Dutch province of Friesland (Frisia) will be extended with a series of crucial datasets and map layers.
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Witnessing the Process of Bacterial Cell Death: Novel Antimicrobials and Their Mechanisms of Action
This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…
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Spectroscopic characterization of exoplanets: From LOUPE to SINFONI
Over the past years it has been discovered that the population of extra-solar planets is large and diverse.
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Societal impact
Research from the Living Lab is important for society. For example, scientists from the Living Lab discovered that the pesticide thiacloprid is up to 2,500 times more harmful to insects than was thought on the basis of regular lab research. Partly because of this discovery, the European Commission decided…
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Year in review FSW 2023
In this year in review we show you various projects we're very proud of. Driven by our values at the Faculty of Social and Behavioural Sciences.
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The International Labour Organisation: 100 years 1919-2019
The International Labour Organisation (ILO) was established in 1919 based on the premise that social justice is a condition for lasting peace. On February 2019 the ILO celebrated its 100th anniversary with an international symposium to consider the future of the ILO.
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Tom van der Wel
Science
t.van.der.wel@lic.leidenuniv.nl | +31 71 527 3534
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Jesse Wichers Schreur
Faculty of Humanities
j.g.wichers.schreur@hum.leidenuniv.nl | +31 71 527 2125
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Thijs Porck
Faculty of Humanities
m.h.porck@hum.leidenuniv.nl | +31 71 527 1611
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Discovery and characterization of new glucosylated metabolites
PhD defence
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Pascal chair 2023
Peter Flach is Professor of Artificial Intelligence at the University of Bristol. An internationally leading scholar in the evaluation and improvement of machine learning models using ROC analysis and calibration, he has also published on mining highly structured data, on knowledge-driven and explainable…
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Programme structure
The Drug Discovery and Safety specialisation consists of compulsory and optional components.
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Leiden University strengthens its focus on Chemical Biology and Medicinal Chemistry with seven new group leaders
Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…
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3rd Annual Leiden Austrian Studies Lecture
On Friday, 29 October 2021 (15.15-17.00), this year’s lecture will be delivered by Prof. Howard Louthan, (University of Minnesota, Minneapolis, USA) at the Faculty Club of Leiden University. It will be titled ‘Revisiting a Renaissance Classic: Theuerdank, Maximilian I (1486-1519) and the Discovery of…
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New LeidenGlobal activities for Leiden2022
With Leiden2022 drawing nearer, LeidenGlobal is busy developing extra activities to demonstrate the knowledge that is present in Leiden and to create interaction with a wider audience. With this valorisation, the partnership between several cultural and academic institutions in Leiden matches the theme…
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Looking at the big world of microbiology through the smallest lenses
Antoni van Leeuwenhoek, the father of microbiology, died 300 years ago. 2023 has therefore been designated the Antoni van Leeuwenhoek year. The new Unimaginable exhibition in Rijksmuseum Boerhaave is about the amazing world that Van Leeuwenhoek made visible. What was so special about the way he worked?…
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The Life and Death of the Shopping City: Public Planning and Private Redevelopment in Britain since 1945
How have British cities changed in the years since the Second World War? And what drove this transformation? This innovative new history traces the development of the post-war British city, from the 1940s era of reconstruction, through the rise and fall of modernist urban renewal, up to the present-day…
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Neanderthals hunted straight-tusked elephants, 125,000 years ago
A Leiden and Mainz (Germany) based team studies the activities of early humans in a 125,000 years old Last Interglacial ecosystem, formerly exposed in a large open cast brown coal pit near Halle (Germany). The Last Interglacial is an important warm-temperate period, showing the full flora and fauna…
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Starting the new year together: these are the winners of faculty awards
A beautiful speech by vice-dean Bart de Smit, a mini-lecture on exoplanets and the presentation of three faculty awards. That's how we started the new year at the faculty. Together with colleagues and students, we raised our glasses to a new year full of great collaborations, science and education.
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Leiden University celebrates 444 years and is coming to you!
Leiden University is 444 years old this year! And we have big plans to celebrate this special birthday in 2019 - together with the people of Leiden and The Hague.
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Kinetic profiling of positive allosteric modulators of the mGlu2 receptor
Supervisor: Maarten Doornbos
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Royal honour for emeritus professor Ad IJzerman
Ad IJzerman, Emeritus Professor of Pharmacochemistry, was made a Knight of the Order of the Lion of the Netherlands on 26 April. He was presented with the royal honour by Mayor Elbert Roest in the town hall in Bloemendaal.
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Organisation
The Leiden Academic Centre for Drug Research (LACDR) is responsible for the research and education in Bio-Pharmaceutical Sciences carried out at Leiden University.
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Night of Discoveries with Leiden University researchers and fun activities
Festival
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Faculty of Science celebrates Chinese New Year
The Faculty of Science celebrated the Chinese New Year on 26 January, with an event that was organised together with the Leiden Science China community. After a warm welcome and New Year Wishes by Dean Geert de Snoo, visitors could participate in various activities, such as a calligraphy lesson.
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History
Life Sciences Artificial Intelligence Data Science
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Glycoproteomics assays for prostate cancer biomarker discovery
PhD defence
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A Hundred Years of Republican Turkey: A History in a Hundred Fragments
As a critical commemoration of its centenary, this book presents a mosaic of one hundred carefully curated fragments by expert authors, shedding light on politics, economy, society, culture, gender, and arts in a hundred years of Turkey.
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Oncode Accelerator
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…
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Determining the kinetic profile of ENT1 inhibitors
Supervisor: Anna Vlachodimou
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Pursuing new anti-cancer therapy as a team
Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…
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Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
- 25 Years after Hillenbrand: New Approaches to Sources Translation and Perspectives
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Unravelling the Homicide Drop: Disaggregating a 25-Year Homicide Trend in the Netherlands
This study assesses nationwide, disaggregated trends in homicide rates over a 25-year period. Using a unique, detailed dataset, spanning a quarter of a century of homicide data allowed Aarten & Liems to assess type-specific homicide trends and the relationship between gender and age within these tre…
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Teaching
At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.
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The Complete Archaeology of Greece
This book covers the story of Greece and its central role in our understanding of European civilization, from the Palaeolithic era (400,000 BP) to the early modern period (1950 AD).
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Zebrafish embryos and larvae as a complementary model for behavioural research
Promotor: Prof.dr. M.K. Richardson