2,048 search results for “cancer date discovery initiative” in the Public website
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UM Cure 2020: New therapies for uveal melanoma
Can we bring novel treatment options to the clinic for UM patients with liver metastases?
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Dutch universities and Elsevier initiate open science partnership
The Dutch universities, university medical centres and Research Council have reached an agreement with Elsevier Publishing on a national open science partnership. The partnership includes open access publishing and reading services for Elsevier journals and open science services for disseminating and…
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Medicinal Chemistry
The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…
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Optically stimulated luminescence dating of Palaeolithic cave sites and their environmental context in the western Mediterranean
The Western Mediterranean is a key region to understand human dispersal events within and out of the African continent as well as for the eventual replacement of Neanderthals by anatomically modern humans during the Pleistocene. Central to any conclusive interpretation of archaeological and palaeoclimatic…
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Prediction of contralateral breast cancer - Statistical aspects and performance assessment
PhD defence
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Mathematics student Lars Pos wins Robbert Dijkgraaf Essay Prize: 'Discoveries find their application in the most unexpected places'
With his essay 'Why science?', mathematics prodigy Lars Pos (18) won the Robbert Dijkgraaf Essay Prize. Within the theme 'The fascinating workings of science', the bachelor student wrote a plea for the societal value of fundamental scientific research. 'Because you don’t know beforehand where we can…
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service-minded and cooperative government is essential in citizens’ initiatives
Legal frameworks are often a pitfall when it comes to citizens’ initiatives. Esmee Driessen, a guest lecturer at the Department of Constitutional and Administrative Law and an expert in citizen participation, conducted research on the support and facilitation of citizens' initiatives. In a Dutch journal…
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Gerard van Westen: 'Our model predicts what candidate drugs do in your body'
He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…
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About the programme
The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Mechanisms of Ewing sarcoma metastasis: biochemistry and biophysics
Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska
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A community effort to assess and improve drug sensitivity prediction algorithms
Source: Nature Biotechnology, Volume 2014, Issue June (2014)
- Leiden Institute of Chemistry
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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Development & Disease in Animal Sciences
Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.
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Bioactive Molecules in Animal Sciences
Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Institute for Chemical Immunology
Overkleeft
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Click-to-release for immune cell activation
This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…
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Optimizing clinical management of T1 colorectal cancer
PhD defence
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Immuno-photodynamic therapy of cancer
PhD defence
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Pax initiative, organizes idealab and presents results to the International Court of Justice (ICJ)
On April 19, Pax Initiative, a youth led NGO, held its first ever event at the Museon in the Hague. The event, “International Court of Justice Idealab: The Future of the ICJ” was a productive and inspiring discussion among students and young professionals on how the Court can reach the 16th Sustainable…
- Leiden Loves Science
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Leiden University Medical Center
In the Leiden University Medical Centre (LUMC) we strive to improve health care and the health of people.
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Dr. Gerard van Westen receives VENI grant
Gerard van Westen (LACDR/division of medicinal chemistry) has been awarded with a VENI grant from NWO, the Dutch Research Council.
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How to develop cancer drugs with less side effects
Lecture, Tuesday Talks: Science Insights
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Three LUF grants for talented Leiden Science researchers
Fighting against cancer, antibiotic resistance and disposable plastics: Ahmed Ali, Fredj Ben Bdira, and Valerio Barbarossa receive a LUF grant for their innovative and socially relevant research. These grants for academic talent are often an important step towards grants by NWO and other grant insti…
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Re‐dating the seven early Chinese Christian manuscripts : Christians in Dunhuang before 1200
Mr. J. Sun defended his thesis on 21 March 2018.
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Explore 'different' food procurement initiatives in the Netherlands during the Voedsel Karavaan
Throughout the year, the organisation 'Voedsel Anders' organizes an events series that showcase various local food initiatives in Dutch cities.
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The environment: victim and initiator of armed conflict
The Third International Conference on Environmental Peacebuilding is set to take place between 19 and 21 June at the Wijnhaven building in The Hague. During the conference, over 400 participants from across the globe will come together to discuss the relationship between the environment and armed co…
- YAL at Night of Discoveries 2023
- About this minor
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Mariana Gkliati presenter at 2nd Annual Conference, Refugee Law Initiative, University of London
'Mariana Gkliati delivered a presentation entitled: 'Accountability of the Europepan Border and Coast Guard Agency: The Litigation Route' at the Refugee Law Initiative's 2nd Annual Conference in London, on Monday 5 June
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Knowledge for the public
Knowledge is everywhere at Leiden University. It is also accessible for those who do not study or work at the University.
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Mariana Gkliati presented at the Refugee Law Initiative International Conference in London
Mariana Gkliati presented on Tuesday 2 June at the 4rth Annual Conference of the Refugee Law Initiative organised at the University of London. The title of the conference was Rethinking the ‘Regional’ in Refugee Law and Policy.
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Helen Pluut involved in interdisciplinary initiative that is awarded a Kiem grant
Leiden University has made available Kiem (seed) grants of €10,000 - an initiative for developing new interdisciplinary, interfaculty research partnerships and encounters. Helen Pluut is part of a Kiem team, one that brings together researchers from Leiden Law School, LUMC, FSW and ICLON (and Young…
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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Single cell technologies for mechanobiology and mechanopharmacology
Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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Medicine/Leiden University Medical Center
We are very happy to welcome you to spend a semester or year studying or doing an internship with us at the Leiden University Medical Center. Here you will find information on your course timetables and registration.
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About the programme
Drug Discovery and Safety consists of 120 European Credit Transfer System (EC) points. NOTE: This specialisation will be integrated into the new specialisation ‘’Research in Bio-Pharmaceutical Sciences’’ as of September 2025.
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Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
- Facilities
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Student-initiative COOP empowers students to discuss difficult topics respectfully
Students are ever more cautious to express their view on controversial debates. The new student-led D&I initiative at the Faculty of Humanities, COOP, is ready to step in. They organise sessions to guide students on speaking up and respecting the views of others at university.
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NMR studies of protein-small molecule and protein-peptide interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Storie del Possibile: Grassroots and Local Initiatives in Italy and Europe
The conference Storie del possibile took place in the Ex- lavanderia of Santa Maria della Pietà in the neighbourhood Monte Mario in Rome, on April 21-22 2018. Maria Vasile, PhD candidate of the "Food Citizens?" project, attended the conference and shares her experiences.
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Master's Open Day: from initial orientation to final choice
Bachelor's students from all different disciplines came to the Master's Open Day to explore the options for their next programme. Some of them visited several different programmes and still have all their options open, while others wanted answers to very specific questions before making their final…