In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

In this dissertation, the life account is constructed of of the founder of Bon Religion, Shenrab Miwo.

On the 1st of December Marcela A. Garcia Probert successfully defended a doctoral thesis and graduated.

Article by Dennis Broeders in the Journal of Cyber Policy on the (im)possibilities of addressing election interference and the public core of the internet in the UN GGE and OEWG.

Using object assemblages to reconstruct activities, modes of deposition and abandonment at the Late Bronze Age dunnu of Tell Sabi Abyad, Syria.

Natascha van der Zwan, Assistant Professor at Leiden Univeristy, together with two other authors, wrote a book that explored some of the ways coronavirus is impacting the global capitalist system – and how this could change for better and for worse.

This perspective addresses four challenges facing theorists whose aim is to make quantitatively accurate predictions for reactions of molecules on metal surfaces, and suggests ways of meeting these challenges, focusing on dissociative chemisorption reactions of H2, N2, and CH4.

Jus post bellum, the body of laws and norms governing the transition from armed conflict to peace, has emerged as a crucial issue for international law scholars, governments, and all concerned with building a just and sustainable peace. The Jus Post Bellum Project, funded by the NWO and hosted by the…

The aim of this study was to provide insight into how teachers in higher education can be supported in the design, implementation and evaluation of group assignments by developing a theoretical and evidence-based framework for the design of group assignments.

How did common people write in the late eighteenth century? Little is yet known on this topic, since our knowledge is mainly based on printed texts written by a small part of the (male) elite population. This dissertation – written from a sociolinguistic point of view – gives us new insights into late-…

Terrorism has been one of the most important threats to peace, security and stability in many parts of the world. But what does this mean? What is the nature of this threat? What can be done about it and how can we at least limit the impact of terrorism?

This book focuses on policing in city-regions in Europe bringing together experts from across the continent to develop a sociology of urban policing and a unique methodology for comparing different metropolises in the same country.

This dissertation presents an in-depth study of the clause-typing system in Ecuadorian Siona.

On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.

Estudio arqueológico de la primera ciudad española en la Tierra Firme de América: Santa María de la Antigua del Darién

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

The Brazilian economy has long been defined by its enormous potential. Over the past 30 years, some of this has at last been realised. Latin America’s largest economy has rapidly risen in global importance while poverty at home has declined. Yet, despite periods of progress, Brazil remains prone to…

Although sexual abstinence before marriage is no longer the central message in The Netherlands the affective relationship as a criterion for professionals within criminal justice can be seen as a more contemporary version of marriage.

On 1 July 2020, Niek Strohmaier defended his thesis 'Making Sense of Business Failure'. The doctoral research was supervised by Prof. J.A.A. Adriaanse en dr. H. Pluut.

This book is the first comparative study of estimative intelligence and strategic surprise in a European context, complementing and testing insights from previous studies centred on the United States. It does extensive empirical analysis of open-source material and interviews in relation to three cases…

Nichiran kankei-shi o yomitoku [Revisiting the History of Dutch-Japanese Relations] is a new, two-volume Japanese publication with a chapter written by Wulan Remmelink. Both volumes offer a new look on the historical relations between Japan and The Netherlands during the Edo period by examining various…

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

Promotor: M. Franx, Co-Promotor: I.F. Labbé

This dissertation studies the formation of the wage laboring class in the Iranian oil industry during the first decades of the 20th century.

This study documents and translates the Saa (Zapotec) cultural heritage of the Bene’ Ya’a/En’ne I’ya peoples, the Zapotec inhabitants of the Sierra Norte of Oaxaca.

In this article, the authors summarise the literature on the effects of multilevel governance on governments’ policy responses to Covid-19.

For the first time, a group of international and interdisciplinary researchers led by Karline Janmaat and her former MSc Student Chirag Chittar, have tested the several hypotheses on music simultaneously in a modern foraging society during their daily search for tubers – their staple food. They found…

Cody Bahir defended his thesis on 1 June 2017.

Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…

This study examines the mutual intelligibility between all 225 pairs of 15 Chinese dialects, in two main branches, i.e., six Mandarin dialects and nine non-Mandarin (Southern) dialects.

Smartphone behaviors are so common but how does the brain generate this behavior? The Cognition in the digital environment laboratory (CODELAB) investigated the brain activity surrounding smartphone interactions with the help of Artificial Intelligence. According to their research, the brain fluidly…

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

On October 31st, Margarita Gulian succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Margarita on this great result.

Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…

This book explores the intellectual history of the Dutch empire from the sixteenth century to the postcolonial era, going beyond systemic thinkers to understand how empire was perceived in day-to-day life. It takes a transnational and transimperial approach to the Dutch empire, connecting European,…

This volume considers the military architecture and its impact on local communities in Rome's eastern frontier, which stretched from the north-east shore of the Black Sea to the Red Sea.

This publication examines the issues regarding the cross-border resolution of financial institutions, focusing on the power allocation between the home and host resolution authorities, i.e. the jurisdiction rule.

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

On 30 September 2021 Babette van Hazebroek defended her thesis 'Understanding delinquent development from childhood into early adulthood in early onset offenders'. The doctoral research was supervised by Prof. J.W. de Keijser and Prof. A. Popma (VUMC).

Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

On 10 March 2021, Pieter Huizing defended his thesis 'Parallel Enforcement of International Cartels and Its Impact on the Proportionality of Overall Punishment'. The doctoral thesis was supervised by Prof. T.R. Ottervanger.

This study looks at the question of how and at what level students in primary teacher education can integrate theory and practice, and how the organisation of their learning environment, focusing especially on mathematics and pedagogy, can contribute to that.

Yi-Wen Cheng defended her thesis on 28 May 2015

This dissertation explores how domestic political power struggles in Greece and Turkey during the Cold War engaged with the ongoing conflict in Cyprus and aims to demonstrate how socialist parties in Greece and Turkey struggled with the concept of the “nation” in battling for power and political positioning…

The thesis wishes to examine the pathways of thought underlying the creative act of music making and the performance practice of complex music from the late twentieth and early twenty-first century.

It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.

Piecing together the urnfield mortuary process in the Lower-Rhine-Basin, ca. 1300 - 400 BC

On Tuesday 23 May 2017, Jasmina Mackic defended her doctoral thesis ‘Proving discriminatory violence at the European Court of Human Rights’. The supervisor of the research is Vice Dean and Professor of Public International Law Larissa van den Herik. A brief summary of her thesis is provided below.

On 16 June 2020, Andrea Varga defended her thesis 'Establishing State Responsibility in the Absence of Effective Government'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. F. Baetens (University of Oslo).