Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

Alumni event, Lecture

Lecture, Annual Leiden Terra Incognita Lecture

PhD defence

The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).

In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is suitable for finding unknown and innovative drug structures, the researchers proved.

Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.

It is a stormy Sunday afternoon, with gusts of a whopping 110 kilometres per hour. Chemist Teun Sweere defies the enormous headwind on his city bike and wins the NK Headwind cycling after 22,5 minutes. A new highlight follows six months later: his PhD defence (14 June).

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…

Lecture

A study of the International Union for Conservation of Nature has identified tree species native to Indonesia’s Kutai National Park that are resilient to climate change. The species support threatened East Bornean orang-utan populations; therefore, the study recommends their use in reforestation efforts.…

Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…

The objective of this study is to better understand the distribution of microplastics in the environment. More specifically, we will quantify the abundance and distribution of microplastics on beaches.

Care conferences for long-term residents (15+ years) in forensic mental health care are widely appreciated by all parties involved. Research by Leiden University shows that the demand for these meetings is so great that the supply cannot be met within the desired time frame.

A catalyst: normally a substance that speeds up a chemical reaction, without adding molecules to this reaction. Scientists from the group of Prof. Marc Koper of Leiden University and Prof. Yang Shao-Horn of MIT now discovered that in specific reactions that need oxygen, catalysts called metal oxides…

Preceding the inaugural address of Reinout Vriesendorp as Professor of Insolvency Law at Leiden University: “***+it happens; then and now” a seminar took place on the underestimated effects of hindsight bias in insolvency cases on 23 June 2016.

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

The "BRAVE NEW WORLD" conference is about how future technology will impact human life. On November 8-9 it is held in Leiden. Two of the invited speakers are researchers and lecturers of the Media Technology program.

Two Leiden researchers of the Institute of Psychology have been given the opportunity to realise their research plans for the coming three years thanks to a Veni grant from the Netherlands organisation for scientific research. Hanneke Hendriks is researcher in the field of Social and organisational…

Every month a member of the Institute for History tells about a book that inspired him or her. Afterwards, the pen is passed on to another colleague. This month dr. Meike de Goede tells about the book 'Between Tides' by Valentin Mudimbe. The novel, little known beyond the circles of Africanists and…

The train to The Hague holds no secrets for Jeroen Touwen anymore. Since October, the Vice-Dean of the Faculty of Humanities has been part of the board of Campus The Hague. One day a week, together with Jan Crijns (Professor of Criminal Law and, as of February 15, Vice-Dean of the Law Faculty), he oversees…

‘Walking around in a new environment activates our brain’s learning centre. This allows us to learn better, even once we’ve returned to a familiar environment.’ This is the conclusion drawn by neuroscientist Judith Schomaker in her recent publication in Neurobiology of Learning and Memory.

Leiden University and LUMC benefit from unique knowledge gained from research and teaching about healthy lifestyles. We want to bring this knowledge together into one place, and we want to share it even more effectively than we do now.

This dissertation provides a novel perspective on the interaction between quantifier scope and ellipsis. It presents a detailed investigation of the scopal interaction between English negative indefinites, modals, and quantified phrases in ellipsis. One of the crucial observations is that a negative…

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

On 6 March, Jelle Klaas, lawyer for the Public Interest Litigation Project of the Dutch Section of the International Commission of Jurists, delivered a lecture to the students of the Advanced Master’s in European and International Human Rights Law at Leiden Law School.

Leiden University Medical Center (LUMC), Leiden University and Philips are jointly receiving over 2 million euros from NWO to set up an artificial intelligence (AI) lab. The aim of this lab is to accelerate and improve MRI scans with AI. This is great for patients, and it helps make MRI more accessi…

On 21 November 2018, Lieke Kools defended her thesis 'Essays on wealth, health, and data collection'. The doctoral research was supervised by Prof. dr. K.P. Goudswaard en Prof. dr. C.L.J. Caminada.

The d12n Research Cluster provides a space for inquiry and intervention into the ongoing digit(al)isation of culture, society, and scholarship. The research cluster aims to link CADS Institute researchers to each other as well as to experts and praticioners from around the world as we combine thinking…

Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years

On 22 November 2018, Teico Sikkema defended his thesis 'Beginsel en begrip van verdeling'. The doctoral research was supervised by Prof. mr. W.G. Huijgen and Prof. dr. F. Sonneveldt.

Madeleine O. Hosli & Jaroslaw Kantorowicz analyze EU states' foreign policy divergence at the UN General Debate, assessing if Lisbon Treaty reforms increased EU cohesion or if states maintain distinct positions.

The project has been done in the Quantum Matter Optics under the supervision of Dr.ir. Sense Jan van der Molen and Dr. Johannes Jobst. The title of the presentation is:

Inspectors at the Dutch Tax and Customs Administration can require people to provide more information relating to their tax returns. Esther Huiskers-Stoop from the Tax Law department investigated the rules in place to protect us when we are required to provide information to the tax authorities.

By looking at stars in dwarf galaxies research Bas Zoutendijk is trying to gain new insight into dark matter.

This thesis discusses the constructions relevant to Object Shift from the intonational perspective, by presenting experimental data from all the Scandinavian languages.

In the 2020 presidential elections, voters in several, mostly southern, electoral districts of the United States saw ‘their’ polling stations closed by the local authorities. In order to cast their vote, they had to travel further or use the mail ballot. Media reports and civil rights activitsts often…

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

The substance galanthamine from flower bulbs can fight symptoms of Alzheimer's disease. Nadeem Akram investigated how daffodils can optimally produce this natural remedy. PhD defence on 24 June.

The introductory meeting of the new evening track Management and Consultancy (MSc Management Public Sector) was held on Thursday 3 February at Wijnhaven. Prof. dr. Frits van der Meer, in charge of the professional Public Administration master programme, welcomed the first cohort of students together…

An international collaboration of astronomers is organising a special online lecture series for physicists and astronomers in Cuba. The reason for this is the tightening of measures against this country, as a result of which researchers can hardly get any information from outside the island. ‘Everyone…

To investigate the effectiveness of an online self-help programme for people with HIV and depressive symptoms.

Natural resources are becoming increasingly scarce. If we want to maintain our current standard of living, we will need inventive solutions. The researchers at the Institute of Environmental Sciences (CML) share their thoughts on how to achieve a fully circular economy in which as little use as possible…

The core curriculum equips students with the conceptual approaches and qualitative empirical research methods necessary to analyze law in context. Specialized electives enable students to dive deeper and focus on particular areas of legal practice—from legal mobilization to regulation and compliance…

On Wednesday 12 December 2018, the department of Child Law, on the initiative of dr. Yannick van den Brink, dr. Stephanie Rap en prof. dr. Ton Liefaard), organized an expert meeting on ‘Equality, children’s rights and digital technologies’. The objective of the meeting was an in-depth exchange of ideas…

The purpose of this programme is to join knowledge and insights from linguistics, literary analysis, and rhetoric, for the purpose of developing a set of methods for the stylistic investigation of any type of text in Dutch.

Organizations often announce their protest activities prior to their implementation to mobilize awareness, recruit supporters, and receive media attention. We are interested in the effectiveness of protest announcements—that is, under what conditions governments make concessions to avoid having an announced…

This summer, the Casimir Research School celebrates its first lustrum. To mark the occasion and to commemorate the fact that Hendrik Casimir would be 100 this summer, his widow Josina Casimir-Jonker has endowed the Research School with a fund to support the activities of master's students.