Mazène Hochane and Xueying Fan have won the fourth annual LION Image Award. They created a detailed colour image of a human kidney in development.

Leiden University has appointed John van Noort as Professor in Biophysics. He studies the way in which our DNA is folded and read out.

An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.

Provenance and distribution of raw materials

An overview of awards and prizes granted to our staff and students in 2019, as well as special appointments and royal distinctions.

Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…

Linguistic research on a unique collection of Dutch letters allowed us to gain access to the every-day language of people from various walks of life. Private letters by men, women and even children have been elaborately explored in the Letters as Loot researchprogramme, initiated and directed by prof.…

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

PhD defence

Sinds september 2010 werken Geerten Waling en Anne Heyer in het NWO project ‘The Promise of Organization’.

Dit jaar begon het project 'Monarchy in Turmoil'. Dit project bracht twee nieuwe onderzoekers naar het Instituut voor Geschiedenis: PhD-kandidaat Quinten Somsen en postdoc Joost Welten. Hieronder stellen zij zich voor en lichten zij hun project toe.

Politicians, public servants and administrators are increasingly expected to be holier than the Pope. This is not necessarily a positive development, in the view of Leiden University lecturer Toon Kerkhoff, who has studied dozens of integrity issues.

Welcome to the 2024-2025 academic year! I hope this finds you feeling refreshed following an enjoyable and restful summer holiday season. As we start the autumn semester, I want to look back briefly by highlighting 10 significant milestones at LUCSoR from this past year (some of which I referenced in…

Conference, (in Dutch and partly in English)

Neanderthals in cold regions probably ate a lot more vegetable food than was previously thought. This is what archaeologist Robert Power has discovered based on new research on ancient Neanderthal dental plaque. PhD defence 1 November.

The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…

A certain type of oil droplets changes shape when cooled and shrunk: from spherical through icosahedral to flat hexagonal. Two competing theories couldn't fully explain this, but now, a Physical Review Letter by Ireth García-Aguilar and Luca Giomi solves the mystery.

In the week of 22 May, a delegation of the Faculty of Science visited Indonesia to strengthen the cooperation with the Universitas Gadjah Mada, the Universitas Indonesia and the Kebun Raja (botanical garden) in Bogor. Furthermore, the delegation visited the faculty of Pharmacy of the Institut Teknologi…

Catalysts are indispensable in everyday life. We know what they do and more or less how they do it, but we still lack a fundamental understanding about their functioning at an atomic scale. Therefore, Irene Groot from the Leiden Institute of Chemistry develops new measuring techniques to unravel the…

Nanodiamonds and charcoal in Dutch soil provide no evidence for the alleged impact of a meteorite at the end of the last Ice Age. This is the conclusion of a research done by Utrecht University in collaboration with Leiden University and the University of Groningen.

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…

Chinese universities have big ambitions to be among the leading international higher education institutions. What does this mean in terms of opportunities for researchers at the universities of Leiden, Delft and Rotterdam? Staff at the universities recently discussed the issue.

‘Working in Leiden is a dream come true.’ Ákos Kovács studied in his birth country Hungary and worked in Germany, Denmark and Groningen. As professor of Microbiome Ecology at IBL, he immediately started working together with his new colleagues to make discoveries about the versatile bacterial species…

Making all those things we normally cannot see visible is the challenge that fascinates Fons Verbeek, Leiden's new Professor of Computational Bio-Imaging. Contributions from chemistry, optics and in particular computational sciences to making and processing these images give greater insight into the…

Research into depression in children, Leiden alumni in the Dutch House of Representatives and an exceptional achievement by one of our students: what do this topics have in common? They are among our most read stories of 2021.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

The €6.24 million EU-funded research project QSPainRelief has kicked off. The project aims to help patients suffering from chronic pain with novel, personalised combinational treatments and is coordinated by Elizabeth de Lange from the Leiden Academic Center for Drug Research.

Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.

The European Commission has officially established Euro-BioImaging – which provides life scientists with open access to a broad range of technologies and resources in biological and biomedical imaging – as a European Research Infrastructure Consortium (ERIC). The Cell Observatory in Leiden is part of…

On 23 November, more than 70 students visited companies at the Leiden Bio Science. This second edition of the BSP Excursion included a fundamentals track and had a special focus on start-ups.

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

Manufacturers produce high-end technology mostly top-down with large machinery, but small particles are able to build structures by themselves from the bottom up. A major challenge is that these particles easily clump together. Leiden physicist Daniela Kraft has developed a method to use this phenomenon…

Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.

The cellular recycling system in zebrafish is capable of eating harmful bacteria and thus resist infections such as tuberculosis and salmonellosis. That is written by Leiden biologists from the group of Annemarie Meijer. Stimulating this form of defence could be used in new treatment methods against…

Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.

Physicists Lucia Bossoni and Martina Huber have been awarded an NWA Ideeëngenerator-grant for research into iron nanoparticles in the brain. These nanoparticles may be linked to air pollution and Alzheimer's disease.

Lecture

Lecture

PhD defence

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

Leiden researchers found a way to measure the tiny forces exerted by pericytes, one of the most elusive, hard to research cell types, which occur in tiny blood vessels. Building on this fundamental science, researchers may eventually find treatments for medical conditions like ischaemia.

Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…

NWO has awarded eleven Leiden researchers a Vidi grant of 800,000 euros. The research subjects range from Cicero and muscle dystrophy to the archaeology of bogs.

For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…

In 2018, the Institute of Environmental Sciences (CML), born out of activism, exists for forty years. The institute celebrated this on 28 June in the Stadsgehoorzaal in Leiden. In the morning, proud directors and researchers looked back and forth. After this several experts discussed the current environmental…

Gerard van Westen has been appointed full Professor or Artificial Intelligence and Medicinal Chemistry. This chair has been jointly created by the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institute of Chemistry (LIC) as part of SAILS, the university stimulus program in Artificial…

On Friday 28 October, Leiden University organized its annual Physics Ladies Day for female high school students. To mark this festive day, we put the spotlight on four female researchers, who talk about their experiences in physics.