Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Overkleeft

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

The current hepatitis B vaccines need to be stored and transported under refrigerated conditions (2-8 degrees C). This dependence on a cold-chain is highly challenging in areas where hepatitis B virus infections are endemic.

Lecture

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

Tijmen Baarda defended his PhD thesis on 8 January 2020

This book examines the history of The Netherlands in a way that connects global processes to local developments.

Source: Eur J Med Chem (2015)

Inspiring and relaxed – these are qualities that describe the Netherlands perfectly. At the same time, there is much more to say about the country. For instance, according to the 2018 UN Human Development Index, the Netherlands is ranked tenth among the best countries to live in.

On 18 April, Alexandre Tavadian defended the thesis 'The International Civil Service: Redefining Its Independence'. The doctoral research was supervised by Niels Blokker and Brian McGarry.

LACDR, the Leiden Institute for Drug Research, developed better tolerated excipients to prevent adverse effects related to the surface of nanosized drugs such as vaccines. LADCR professor of Biopharmacy Matthias Barz and Polypeptide Therapeutic Solutions (PTS) are collaborating to develop processes…

The transition to new and renewable energy sources should be completed by 2050. Researchers in various disciplines at Leiden University are conducting unique research that will help us make this transition and reduce CO2 emissions.

The more opportunities a child has to learn and develop, the stronger his or her future position in society. Leiden University investigates how the brain picks up information, and how learning processes can be influenced positively.

Governance is a complex puzzle of organisations, people and divergent interests. Academic research in this field furthers our knowledge of the role of public administrators, of different organisational structures, of the people who work at such organisations and of how these organisations implement…

A punishment that fits the crime is the cornerstone of the rechtsstaat or constitutional state. But opinions differ greatly on what constitutes a just and effective punishment. Research by Leiden University provides politicians, legislators, law enforcers and the public with new information and insights…

Issues such as climate change, the depletion of natural resources or social inequality are too complex to be addressed from a single scientific discipline or by a single country. Leiden University has the expertise to bring the resolution of these enormous problems a small step closer.

The worldwide race to the quantum computer is in full swing. This computer can take on computing tasks that we can only dream of today, such as finding proteins that can be used as medicines in seconds flat. Leiden physicists have discovered how the Majorana particle can be used as a building block…

Astronomers want to understand the Universe, from the Big Bang to the present day, and what the future will hold. In Leiden they focus on two key questions: ‘How did stars and planets originate’ and ‘How were galaxies and black holes formed in the young Universe?’ A new generation of telescopes – just…

PhD defence

PhD defence

PhD defence

PhD defence

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

Inaugural lecture

Inaugural lecture

Inaugural lecture

PhD defence

PhD defence

Inaugural lecture

Inaugural lecture

Inaugural lecture

Grootschalige productie van batterijen voor elektrische auto’s zwakt de emissiereductie die door elektrisch rijden wordt behaald af.

The Dutch Minister for Infrastructure and Watermanagement Cora van Nieuwenhuizen has offered the first copy of the book ‘Behind and Beyond the Chicago Convention: The Evolution of Aerial Sovereignty’ to the Secretary-General of the International Civil Aviation Organization (ICAO).

Den Haag is de stad van vrede en recht. Rondom deze thema’s organiseren culturele en maatschappelijke organisaties het festival. De Universiteit Leiden is nauw betrokken bij de organisatie. Universitaire medewerkers en studenten doen bijvoorbeeld mee aan de Vredesloop, Marieke Liem van het Institute…

In zijn oratie bepleit Joachim Koops dat de toekomst van Security and Global Affairs ligt in onderzoek, onderwijs en academisch bestuur.

Voormalig demissionair staatssecretaris van Fiscaliteit en Belastingdienst Marnix van Rij gaf op 17 juni in samenwerking met universitair docent Esther Huiskers-Stoop een gastcollege over belastingrecht en duurzaamheid. Deze lezing werd op initiatief van student Darya de Wilt georganiseerd.

Gaan vaders minder werken als andere vaders dat ook doen? Helpt betaald ouderschapsverlof hen om meer op te pakken in het huishouden? Hoe bepalend zijn sociale normen voor verschillen op de arbeidsmarkt? Onderzoeker Max van Lent gaat het uitzoeken.

What do you derive your self-esteem from? Not a question you would quickly expect in a course on leadership. Lecturer Michel Don Michaloliákos opted for a unique approach to 'A Taste of Leadership', an Honours course with introspection as its core theme.

Het National Ocean Decade Committee heeft twee nieuwe leden benoemd van de Universiteit Leiden. Hilde Woker en Renate Reitsma zullen zich als leden van dit comité inzetten om het het belang van oceaanwetenschappen te promoten.

Het nieuwe kabinet is uniek, met vier coalitiepartijen en een niet gekozen minister-president. Hoogleraar Staats- en Bestuursrecht Wim Voermans analyseert het kabinet in een opiniestuk voor het NRC, en beschrijft een instabiele en ongekende situatie.

What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?

Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.

Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

A portrait of the complex historical process of over 500 years of European colonialism in the New World.