927 search results for “effective date development” in the Public website
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Optically stimulated luminescence dating of Palaeolithic cave sites and their environmental context in the western Mediterranean
The Western Mediterranean is a key region to understand human dispersal events within and out of the African continent as well as for the eventual replacement of Neanderthals by anatomically modern humans during the Pleistocene. Central to any conclusive interpretation of archaeological and palaeoclimatic…
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More effective data-driven policymaking
More collaboration, combining data and asking the right questions. These are a few of the recommendations that policymakers and researchers formulated at the conference 'Data gedreven Beleidsontwikkeling' on 28 November 2017.
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Impact of plant hormones on growth and development of actinobacteria
Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.
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The integration of meta-analysis and classification & regression trees: meta-CART
In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Governance, Economics and Development (BSc Major of Liberal Arts and Sciences: Global Challenges)
Wrenching poverty, global inequality, violent political and ethnic strife, deadlocked, unresponsive or even collapsing governments, growing dissatisfaction with democracy and missed opportunities for innovation – these are merely some of the challenges of governance and development with which our programme…
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The placebo effect: first world congress in Leiden
Medicines can work even if they have no active ingredient. The first international scientific conference on placebos will take place in Leiden from 2 to 4 April. Placebo researcher Andrea Evers, who is also chairing the conference, answers some pressing questions.
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Development of life cycle assessment for residue-based bioenergy
What are the key issues in conducting LCA of bioenergy systems? What is the environmental sustainability status of second generation bioethanol? How much would the final results of biogenic carbon neutrality assumptions deviate from the true values based on a complete inventory? How to assess the impact…
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Developing drawing skill: Exploring the role of parental support and cultural learning
Drawing is one of the most unique human behaviours. Like language, drawing is a mode of communication and a cognitive tool that from an early age allows us to interact with others. Is the early development of drawing skill influenced by the social environment? If so, how?
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The chemistry behind cancer drugs: searching for fewer side effects
PhD candidate Dennis Wander searches for the best of both worlds. That is to say: a cancer drug that is effective and also has minimal side effects. To this end, he makes new molecules inspired by two existing medicines. And not without result: ‘We have created a new variant that is very promising.’…
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Understanding delinquent development from childhood into early adulthood in early onset offenders
On 30 September 2021 Babette van Hazebroek defended her thesis 'Understanding delinquent development from childhood into early adulthood in early onset offenders'. The doctoral research was supervised by Prof. J.W. de Keijser and Prof. A. Popma (VUMC).
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Internationalisation of the bachelor's programme in Cultural Anthropology and Development Sociology at Leiden University
What are the social, cultural, and/or educational consequences and challenges linked to the introduction of the international bachelor's programme in Cultural Anthropology and Development Sociology?
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Taking Up Space: Waste and Waste Labor in Developing South Korea
On 25 January 2024 H.J. Pak successfully defended a doctoral thesis and graduated.
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Planning for a World beyond COVID-19: Five Pillars for Post-Neoliberal Development
In this opinion article published in World Development, the authors present five research and policy priorities. While it is clear that ‘pluriversal’ designs need to guide the way forward (Kothari et al 2019), defining a set of key pillars can provide direction and purpose across this pluriversality.…
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Re‐dating the seven early Chinese Christian manuscripts : Christians in Dunhuang before 1200
Mr. J. Sun defended his thesis on 21 March 2018.
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Student agency in secondary school: The development of student agency in secondary schools
Student agency is defined as the ability to increasingly take control of the learning process. It is associated with better grades, well-being, motivation and self-confidence. This research aims to provide teachers tools to stimulate student agency and to monitor its growth.
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Development of an in vitro vascular network using zebrafish embryonic cells
One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.
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Development of novel metabolomics & systems pharmacology concepts to realize personalized medicine
The predication of the effect (efficiency and toxicity) of a drug in a patient is very important in (i) clinical decision support and (ii) the development of novel drug treatments.
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The development of an assessment procedure for beginning teachers of English as a foreign language
This dissertation reports on the requirements for the design and development of teacher assessments, and examines the possibility of developing an assessment procedure that complies with the formulated requirements.
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Emotions and the psychosocial development of children with and without Developmental Language Disorder
Dissertation
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Development of an in vitro vascular network using zebrafish embryonic cells
How can we culture an artificial vascular network to support tissue development ex vivo?
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Controlling anxiety in late life (CALL)
Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…
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Development of cross-protective influenza A vaccines based on cellular responses
Seasonal influenza vaccines provide protection against matching influenza A virus (IAV) strains mainly through the induction of neutralizing serum IgG antibodies. However, these antibodies fail to confer a protective effect against mismatched IAV. This lack of efficacy against heterologous influenza…
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Development of automatic image analysis methods for high-throughput and high-content screening
Promotor: B. van de Water, Co-Promotores: J.H.N. Meerman, F.J. Verbeek
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Development of new chemical tools to study the cannabinoid receptor type 2
The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.
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The Effects of Legal Measures to Empower Supervisory Directors
In their article; The Effects of Legal Measures to Empower Supervisory Directors: Evidence from a Financial Distress Perspective, Santen and De Bos discuss the relationship between the corporate governance structure of a company and its financial performance. Until now studies predominantly hypothesize…
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Elastic Leidenfrost Effect on cover of Nature Physics
First author Scott Waitukaitis and principal investigator Martin van Hecke have made the cover of Nature Physics with their publication on a newly discovered effect. The Elastic Leidenfrost effect explains why hydrogel balls jump around on a hot plate making high pitched sounds.
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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PKPD and disease modelling in therapy development for amyotrophic lateral sclerosis (ALS)
We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.
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Environmental assessment and guidance for the future offshore wind energy development
This thesis aims to address offshore wind energy (OWE)-related environmental impacts.
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induction programs on beginning teachers'well-being and professional development
This thesis reports on the influence of induction programs on beginning teachers’ well-being and professional development, and the essential characteristics of an induction program. These topics were explored by means of an interview study and large scale survey study.
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Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice
Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.
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mRNA boosters are the most effective upon receiving Janssen vaccination
A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…
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ZF-CANCER - Developing high-throughput bioassays for human cancers in zebrafish
How can zebrafish research help to understand and fight human cancer?
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: J.N. Kok, Co-promotor: F.J. Verbeek
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Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Opening Minor Sustainable Development
The new CML minor Sustainable Development started on Monday 7 September 2009 with an official opening by the Vice-Rector Prof. Rietje van Dam.
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Parallel developments in floral adaptations to obligate moth pollination mutualism in tribe Phyllantheae (Phyllanthaceae)
This article discusses the coevolution of several species of the tribe Phyllantheae and moths of the genus Epicephala.
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Digitizing security: How digital risk-profiling is developed in practice
How are digital risk-profiles developed and used in practice?
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Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
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Bòsò Walikan Malangan: Structure and development of a Javanese reversed language
On the 24th of October, Nurenzia Yannuar successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Nurenzia on this achievement.
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Effect of insecticides on damselflies greater than expected
The latest research from the Leiden outdoor laboratory ‘Living Lab’ shows that the insecticide thiacloprid strongly influences even the most common and robust dragonfly species in the Netherlands. The study was published in the Journal of Applied Ecology.
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