PhD defence

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

Coordination chemistry is the chemistry of metal atoms

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

PhD defence

Lecture

Nationale Week Zonder Vlees is een landelijke campagne en wordt breed gedragen door diverse partners uit de voedselindustrie!⠀

An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…

We study how communication can heal and harm when patients are confronted with an illness. Most of our studies focus on serious illnesses such as advanced cancer. Communication lies at the heart of medicine, yet we do not always know which specific communication helps patients. Moreover, many complaints…

SAILS (Society, Artificial Intelligence and Life Sciences) is a universitywide initiative aimed at facilitating collaboration across disciplines on the use of Artificial Intelligence (AI). It is one of Leiden University's interdisciplinary programmes.

Sonorous phenomena are always on the verge of becoming something else. As it unfolds, sound constitutes spaces, mediates presence, articulates time. Furthermore, it may prompt emotions, generate awareness, organise patterns of behaviour or trigger a sense of belonging. As sound becomes audible, it is…

Wordt het nog wat met de Arabische lente?

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…

The NEASQC project brings together academic experts and industrial end-users to investigate and develop a new breed of Quantum-enabled applications that can take advantage of NISQ (Noise Intermediate-Scale Quantum) systems in the near future. NEASQC is use-case driven, addressing practical problems…

NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.

Can we bring novel treatment options to the clinic for UM patients with liver metastases?

With his essay 'Why science?', mathematics prodigy Lars Pos (18) won the Robbert Dijkgraaf Essay Prize. Within the theme 'The fascinating workings of science', the bachelor student wrote a plea for the societal value of fundamental scientific research. 'Because you don’t know beforehand where we can…

The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…

PhD defence

He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…

The two-years MSc programme spans the entire spectrum of Analytical BioSciences, Biopharmaceutics, Drug Delivery Technology, Medicinal Chemistry, Pharmacology and Toxicology.

PhD defence

PhD defence

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Overkleeft

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

The Netherlands-Flemish Institute is offering an internship in Cairo from January 2019 onwards. If you are interested please apply before 20 December, 2018. (See the details in Dutch only)

The Netherlands-Flemish Institute in Cairo is offering an internship from September 2019 onwards. If you are interested please apply before 15 July, 2019. (See the details in Dutch only)

The Netherlands-Flemish Institute is offering an internship in Cairo from March 2018 onwards. If you are interested please apply before February 15, 2018. (See the details in Dutch only)

Lecture, Tuesday Talks: Science Insights

Gerard van Westen (LACDR/division of medicinal chemistry) has been awarded with a VENI grant from NWO, the Dutch Research Council.