The cultural sector, shut down by the corona pandemic, must urgently look for new ways to generate income.

Research often theorizes about young adults and their social media use. John Boy wants to investigate social media platforms by talking to users rather than talking about them

It was a soggy Friday, but the visitors to the Master's Open Day were made of sterner stuff. Bachelor's students from all around the world defied the rain and wind to take a look at Leiden and The Hague to find out more about master's programmes and to get to know the cities themselves.

The 'language analysis interview' on the basis of which the Immigration and Naturalisation Department attempts to determine where an asylum-seeker without any documents comes from, does not meet the criteria of reliability and validity. Joachim Detailleur, student of Arabic, substantiates this statement…

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

TRANSVAC is a collaborative infrastructure project funded by the European Commission (EC), initially under the 7th Framework Programme (FP7) and currently under Horizon 2020. The project is a joint effort of leading European groups working in the field of vaccine development, and is coordinated by…

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

A comprehensive analysis of Nietzsche's conception of conflict and the way in which relations of struggle condition the organisation of complex systems (with a specific focus on the human psyche and the body politic).

A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…

Research at the BPOC/SSNMR group is comprised of the following research themes:

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Intrigued by the way cells autonomously regulate their fate, we strive to understand and visualize cellular processes as the basis of Cell Signaling.

Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.

Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…

We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.

In Europe, archaeological traces of fire become more frequent between 300,000 and 400,000 years ago; but could the earliest occupants have survived without fire for at least half a million years before this? How could the early occupants of Europe have kept warm and processed meat without fire?

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…

How and why latex bearing plants select specific chemical compounds for eco-chemical interactions with its biotic factors?

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Leiden has a strong tradition in theoretical physics, thoroughly linked with experimental disciplines.

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

In Microbial Sciences, we perform multidisciplinary research to understand the structure and function of microbes at all levels of biological organization, from small molecules and cellular structures at atomic resolution to multicellular communities.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

A major goal of ABS research is to overcome one of the major bottle-necks in metabolomic research: the lack of a high-throughput infrastructure in which thousands of samples can be processed in a standardized and cost-effective way (max. a few tens of Euro’s per sample for a full metabolome profile).…

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

The Altai region has yielded a cluster of Middle and Upper Paleolithic stratified sites that have been recently excavated using a multidisciplinary approach.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Does a moving hybrid zone leave a genomic footprint?

Delineating psychophysiological endophenotypes of social anxiety disorder

The portal for prospective Indonesian Students contains information about the possibilities to study at Leiden University in the Netherlands.

Working for a top faculty? Discover the vacancies at the Faculty of Science and apply immediately.

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Is it possible to synthesize industrially relevant compounds in a sustainable manner through the use of light-capturing cyanobacteria?

How does invasive hybridization affect threatened native species?

How did toxin genes evolve from harmless physiological genes?

Can we find new chemical and biological sensing routes on the edge and surface of graphene to improve the potential of graphene to act as a sensor?

All research at Leiden University is organised into institutes. To do justice to the wide spectrum of research (and consequently teaching) that comes from these, you will find descriptions of all the Leiden institutes on these pages.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

Our scientists working with laboratory animals undergo training on animal experiments. In this training, researchers learn how to handle laboratory animals responsibly. Read more about the requirements we set for researchers working with laboratory animals.

In the master’s specialisation Molecular Genetics and Biotechnology at Leiden University students are trained by experts in the areas of molecular biology, microbiology, plant genetics, cellular imaging, animal disease models, and various –omics technologies and the corresponding bioinformatics.

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