PhD defence

The research team

Lecture, PCNI Research Seminar

Currently, Navigation Lab Leiden works on three main themes: navigation ability, spatial abilities, novel techniques in neuropsychology.

The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…

The research of the group Learning and Behavior Problems in Education addresses learning difficulties in the areas of reading (technical reading and reading comprehension) math and writing, and examines learning-related behaviors behaviors.

Throughout the twentieth century, scholars, artists and politicians have accused each other of “historicism.” But what exactly did this mean? Judging by existing scholarship, the answers varied enormously. Like many other “isms,” historicism could mean nearly everything, to the point of becoming mea…

The recent terrorist attacks in Europe are presumably not just acts committed by individuals, but acts facilitated by larger jihadist networks. But how do such networks operate? Understanding their modus operandi can be useful knowledge to counter terrorist threats.

Here you can find products and research tools developed by the Navigation Lab Leiden

Animal Sciences’ contribution to the Bioactive Molecules research theme includes research on molecules from natural sources, such as plants, insects, and snake venom, with the aim to identify novel anti-cancer, anti-inflammatory, anti-microbial, and anti-diabetic agents.

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

Developmental and Educational psychology is concerned with the developmental course and dynamics of cognition, self-regulation, and emotional competence, and the implications for educational and clinical practice.

How can educators in non-STEM fields integrate Climate Change Education to enhance students’ knowledge, skills, and resilience?

Article by Annemarie Samuels in History and Anthropology

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

Psychology graduates acquire skills useful in a variety of jobs. Whether helping people with mental disorders, researching the brain or deciding who should be hired at a company, psychologists can do it.

Festival, Citizen Science

The brain structure of young people with conduct disorder differs significantly from that of their typically developing peers. This is the conclusion of an international study that analysed more than two thousand MRI scans, recently published in The Lancet Psychiatry. Dr Moji Aghajani, one of the principal…

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.

The research of the Van Eck Group focusses on 3 interconnected research lines: 1) Identification and therapeutic targeting of key pathways/regulators in macrophages essential for prevention of atherosclerotic lesion development or stimulation of regression of existing lesions, 2) Atherosclerosis as…

CERQ is a questionnaire measuring cognitive coping strategies developed by Dr. Nadia Garnefski and Dr. Vivian Kraaij.

PhD defence

PhD defence

PhD defence

In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.

The research carried out within the unit Health, Medical and Neuropsychology investigates the psychological factors of health and disease, and the development of innovative treatment.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Using brain imaging to discover the area in the brain that recognizes emotion.

There's a myth that people with autism avoid eye contact in conversations. This can come across as indifferent. Unjustified, stresses Jiayin Zhao, who is doing her PhD research on the socio-emotional development of children with autism. 'That people with autism don't care is anything but true.'

What are the functions of the endocannabinoid system?

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

This thesis describes a study from both a theoreticaL and an experimental point of view.

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Dr. Pauline Aarten tries to find answers of the impact a road traffic accident has on the victims and surviving relatives and how we can improve their position.

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

Deficiency of glucocerebrosidase (GBA) underlies Gaucher disease, a common lysosomal storage disorder. Carriership for Gaucher disease has recently been identified as major risk for parkinsonism. Presently, no method exists to visualize active GBA molecules in situ. We here report the design, synthesis…

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

Legitimacy is generally a term that is associated with the state. The term surfaces when there are problems with state legitimacy—when it is lacking or absent. This present volume attempts to think through the relevance of the concept of legitimacy for other political actors than the state.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

We investigate emergent structures and dynamics of soft materials self-assembled from microscopic constituents.

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

Cognitive psychology is the study of cognitive functions such as attention, memory, consciousness, emotion, language and action control. The goal is to understand the complex relationships between brain, mind and behavior.

Develop EPR instrumentation and methodology to investigate intrinsically disordered proteins (IDPs).

How do genetic and environmental factors make us vulnerable to depression?

Consensus and harmony or balance and reciprocity?