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Do you want to know more about the master's specialisation Education and Child Studies and what it's like to study in Leiden?
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Information activities
Get to know us through our online and in-person events for prospective students!
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Information activities
Get to know us through our online and in-person events for prospective students!
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Social Science Matters: Climate change
Climate change is a hot topic and constantly in the news. Thousands of Dutch high school students protested at the Malieveld in The Hague. News website Nu.nl has barred climate change deniers from their comments section to prevent ‘fake news’. How does climate change impact the research community, and…
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Social Science Matters: Confidence in the future?
After a long period of formation, the Rutte III cabinet presented itself on 26 October 2017. The coalition agreement on which ministers will build is called ‘Vertrouwen in de toekomst’ ('Confidence in the future'). But what impact will this new cabinet have on our future? We asked our researchers in…
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Art & Activism: Resilience Techniques in Times of Crisis
This book examines how renewed forms of artistic activism were developed in the wake of the neoliberal repression since the 1980s.
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FLAMINGO: dark matter, ordinary matter, and neutrinos in the biggest cosmological simulation ever
Not only dark matter, but also ordinary matter and dark energy are tracked in the largest ever cosmological computer simulation ever. In the FLAMINGO simulations, you can see virtual galaxies and clusters of galaxies emerging over the course of billions of years. This is no easy task: with more than…
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Conflict Resolution Seminars @Leiden
COI@Leiden organises activities and events throughout the year. These include a monthly seminar series on topics relating to conflict resolution and PhD labs to assist COI students in developing their research skills.
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Empirical Methods in Legal Research
COI@Leiden organises activities and events throughout the year. These include a monthly seminar series on topics relating to conflict resolution and PhD labs to assist COI students in developing their research skills.
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Activating the Research Methods Curriculum: A Blended Flipped Classroom
The blended flipped classroom is a partially online, partially offline course to teach social science research methods. Online, students watch video lectures, do readings, and complete short exercises to acquire basic knowledge of research methodologies and academic skills.
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Periphery Matters: A Cultural Biography of Peking Opera in Hong Kong
Pui Lun Chan defended his thesis on 12 September 2017
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Team 2 enriching and activating education & blended faculty
This team will investigate how the bachelor can add more depth and reflection to the factual knowledge.
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Activity-based protein profiling for drug discovery
Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…
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Social Science Matters: The surveillance society
Those who know their dystopian classics will inevitably associate the concept of surveillance society with the all-knowing oppressive force characterized as Big Brother in George Orwell’s novel 1984. However, surveillance permeats our society in many more subtle aspects than our worst fears about spy…
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Social Science Matters: The stressed society
Stress, burnout, depression – these conditions pervade all levels of our society. Children and students suffer from constant pressure to achieve; at the international level, tensions lead to short-sighted actions; and, at the personal level, stress affects our health and social environment. How do our…
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Applications for activity-based probes in biomedical research on glycosidases
Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.
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Marie Curie grant for dark matter
Leiden Observatory is going to use a new technique to carry out calculations on gravitational lensing measurements. They will do this is the context of research into the formation of elliptical galaxies. Alessandro Sonnenfeld (University of Tokyo) who developed this technique joined the research team…
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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…
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Pair configurations to molecular activity coefficients: PAC-MAC
This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.
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biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
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Social Science Matters: scientist about voting behaviour
How do people vote? How rational are voting choices? How much do external factor weigh in? In this article social scientis provide some background.
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Synthetic model microswimmers near walls
Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.
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Graduiertenkolleg 'Family Matters' (München)
A new Graduiertenkolleg opens at the LMU.
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Why fundamental science matters
Why do we need fundamental science? For a lot of reasons, speakers showed at the Lustrum Symposium ‘Science Matters’. This symposium was held on 18 March 2016 to celebrate the 200th anniversary of the Faculty of Science.
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From Data to ACTive lifestyle in Wheelchair users (D-ACT-Wheel)
Making the Virtuagym e-platform suitable for wheelchair users with a spinal cord injury or lower limb amputation.
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Black holes with ‘dreadlocks’ offer insight into quantum matter
Physicists understand little about quantum matter, which is a building block of future quantum computers. Theorists have now discovered that black holes with ‘dreadlocks’ harbor a similarly exotic order pattern, which makes calculations on quantum matter easier. Publication in Physical Review Letter…
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Galaxy without dark matter discovered
Astronomers led by Pieter van Dokkum have discovered a galaxy that barely contains any dark matter, which actually proves that dark matter does indeed exist. The research results will be published this week in Nature.
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Family matters
Brothers and sisters within a family, with the same parents, experience their upbringing differently. As well as the impact of their own negative experiences, the way siblings experience their upbringing also plays an important role in anxiety and depression. This is the conclusion reached by Marie-Louise…
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Macrophage activation and cholesterol accumulation in atherosclerosis development
Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck
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Major NWO subsidies for research on dark matter and quantum experiments
Astronomer Koen Kuijken and physicist Tjerk Oosterkamp have each been awarded a major subsidy by NWO. The funding will allow them to construct new research facilities.
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Development of Quantitative Nanostructure Activity Relationship (QNAR) Models Predicting the Toxicity of Metal-based Nanoparticles to Aquatic
Describe and identify what dosimetry parameters are of importance to interpret dose-response relationships (eg., mortality, sub-lethal, growth or reproduction inhabitation, DNA damage and reactive oxygen species, etc. ) for metal-based nanoparticles? How to develop quantitative models that enable to…
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Elmer Maurits
Science
e.maurits@lic.leidenuniv.nl | +31 71 527 2727
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Hermen Overkleeft
Science
h.s.overkleeft@chem.leidenuniv.nl | +31 71 527 5037
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Riccardo Mancinelli
Science
r.mancinelli@cml.leidenuniv.nl | +31 71 527 2727
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Dennis Hetterscheid
Science
d.g.h.hetterscheid@chem.leidenuniv.nl | +31 71 527 4545
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Chenguang Gao
Science
c.gao@cml.leidenuniv.nl | +31 71 527 2727
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Kristell Penfornis
Faculteit der Sociale Wetenschappen
k.m.penfornis@fsw.leidenuniv.nl | +31 71 527 2727
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Social Science Matters: How useful is deprivation of liberty?
A new bill is currently under debate in the Netherlands, advocating raising the prison sentence for manslaughter from 15 to 25 years. ‘This very serious crime (...) evokes feelings of disgust and insecurity in society’, Dutch Minister for Justice and Security Grapperhaus comments on the sentence that…
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Social Science Matters: The (non)sense of conspiracy theories
Climate change is made up, the secret services murdered Pim Fortuyn and JFK, and the moon landing was a fake show. Conspiracy theories are of all times, providing sensation and entertainment, but also unrest and fear. The corona pandemic is new fuel for conspiracy theorists who set fire to 5G masts,…
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Felix Frohnert
Science
f.frohnert@liacs.leidenuniv.nl | +31 71 527 2727
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Havar Solheim
Faculty of Humanities
h.a.s.solheim@hum.leidenuniv.nl | +31 71 527 5342
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Michiel Hogerheijde
Science
michiel@strw.leidenuniv.nl | +31 71 527 5590
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The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
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Uncovering galaxy evolution and the nature of dark matter
Dark matter represents around eighty per cent of the total mass in the Universe. Yet, we still don't really know what it's made of. Astronomer Pavel Mancera Piña is looking for answers. With a Veni grant from NWO and the most advanced telescopes, such as the James Webb Space Telescope, he will investigate…
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Private active cyber defense and (international) cyber security—pushing the line?
This article on private active cyber defense by Dennis Broeders is part of a special issue of the Journal of Cybersecurity, based on a selection of contributions taken from the 2019 Conference on Cyber Norms organized by The Hague Program for Cyber Norms.
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inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Louwerse & Van Vonno, ‘Moving up or down: parliamentary activity and candidate selection’
How do parliamentarians secure their political future? Are their activities in the legislature connected to their place on the candidate list from one election to the next? Political scientists Tom Louwerse and Cynthia van Vonno examine the Dutch case. Their main finding is that speaking in the plenary…