2,125 search results for “war on drug” in the Public website
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Hour of Remembrance on 4 May: ‘We commemorate war victims and draw links to the present’
During the ‘Hour of Remembrance’ on 4 May, the University community remembers its students and staff who were killed in the Second World War. It also looks at freedom and oppression today. Three questions for Sara Polak, chair of the Hour of Remembrance committee.
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Queen Máxima inspects zebrafish embryos
On Wednesday the 4th of September, Queen Máxima opened the renovated tropical greenhouse complex of the Leiden Hortus Botanicus. At the occasion Máxima met with IBL-PhD student Mahin Ghorbani from Iran and talked with her about her work on drug discovery from Iranian medicinal plants using zebrafish…
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A hornets’ nest: Leiden University during the Second World War
‘That hornets’ nest in Leiden must be destroyed,’ said Dutch National Socialist Party member Robert van Genechten in November 1942. He was referring to Leiden University. Why this hatred? Emeritus Professor of University History Willem Otterspeer has written a book about Leiden University during the…
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Growth Fund invests many millions in faster and more sustainable (cancer) drug development
On 14 April, the National Growth Fund awarded million euros in grants to two consortia in which Leiden's science faculty is involved. Pharma-NL will receive 80 million euros and Oncode-PACT 325 million euros. Pharma-NL wants to make medicines available to the patient faster and more sustainably. Oncode-PACT…
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Pregnant and drug dependent: Ministry of Justice tries to intervene with prosecution
Drug use during pregnancy seems like a choice without any consequences. However, the Dutch Public Prosecution Service (OM) has decided to prosecute a mother for using alcohol and drugs during her pregnancy. Mariëlle Bruning, Professor of Child Law, tells current affairs programme ‘Nieuwsuur’ that she…
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Marieke Liem in The Economist on drug-related murders in Europe
Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years
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LUF grant to take the war out of children
Sandy Overgaauw has been awarded a 25,000 euro grant from the LUF for her research into PTSD in Syrian refugee children in the Netherlands. The research should lead to a screening method that can be used to determine which children are at higher risk of developing posttraumatic stress disorder (PTSD…
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Adjudication of war crimes: Keeping sight of cultural sensitivities
Courts that adjudicate war crimes or other crimes against humanity are increasingly taking regional norms and cultural values into consideration. PhD candidate Seun Bakare examined whether this could also be an asset in cooperation with the International Criminal Court (ICC).
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Rob van Wijk discusses the role of zebrafish in drug discovery
Rob van Wijk gave an interview on the role of zebrafish in drug discovery and development, published in FIGON’s journal Medicines as a preview of LACDR’s representation at the PhD competition during the Dutch Medicines Days (DMD). The entire interview can be read below.
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The role of glomerular filtration and active tubular secretion in predicting renal clearance in children using population pharmacokinetic and
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Drugs with fewer side effects through a collaboration between LACDR and PTS
LACDR, the Leiden Institute for Drug Research, developed better tolerated excipients to prevent adverse effects related to the surface of nanosized drugs such as vaccines. LADCR professor of Biopharmacy Matthias Barz and Polypeptide Therapeutic Solutions (PTS) are collaborating to develop processes…
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Fighting cancer with light (and a drug that self-assembles into nanoparticles)
Chemotherapy that does not harm the body, but effectively fights cancer cells: that is the goal of chemist Sylvestre Bonnet and his team. During his PhD research, chemist Xuequan Zhou brought that goal a little closer. He developed molecules that, upon injection in the bloodstream, self-assemble into…
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In war crimes, commanders do not have legal immunity
In her capacity as a lawyer and expert in International Humanitarian Law and Human Rights, Professor Helen Duffy is filing a lawsuit against the Dutch State. Leiden University’s weekly newspaper Mare reports that through her role, Duffy is assisting a Palestinian Dutchman whose family was killed in…
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Using AI to Combat Drug Resistance - an Interview with PhD student Rosan Kuin
Rosan Kuin started her PhD in July at the LACDR under supervision of prof. Gerard van Westen and Dr. Meindert Lamers. She completed a BSc. in Pharmaceutical Sciences at the VU University in Amsterdam in 2017. After that she started two master programs, Drug Discovery & Safety with a specialization in…
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Experts on the war in Ukraine, two years later: ‘Europe learned a lot from the war, help each other and don’t give up’
The one-day symposium ‘War in Europe: the impact of Russian aggression in Ukraine two years on’ on 23 February 2024
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Ovalbumin coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice
The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…
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Anneleen van der Meer
Faculty Governance and Global Affairs
a.van.der.meer@fgga.leidenuniv.nl | +31 70 800 9506
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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COVID-19 Research and Education at Leiden Academic Centre for Drug Research
Since the start of the Corona crisis, several COVID-19 related research and teaching projects were started at LACDR. The computational and teaching activities started right away, as well as a large-scale metabolomics screening program by Thomas Hankemeier’s group. Other experimental activities are still…
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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Project TARGET: gun violence and firearms trafficking in Europe”
Project TARGET aims to improve our understanding of gun violence in Europe and the relationship between gun violence and firearms trafficking.
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Research projects
An overview of research projects at the Predictive Pharmacology group.
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3 October University: from Russian DNA to drug-related violence
In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…
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Design and application of dextran based cross-linked networks
This thesis describes the design, characterization and application of dextran based crosslinked network.
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…
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Does Trump have the authority to single-handedly take on Mexican drug cartels?
The American president Trump is considering military intervention in Mexico to get rid of the drug cartels once and for all, but Mexico is not interested in other countries' interventions. According to Jelle van Buuren, Assistant Professor at the Institute of Security and Global Affairs, Trump's much…
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Dutch creative with food during World War II
During the Dutch famine of 1944–45, people were much more creative in finding food than we thought. Biology student Tom Vorstenbosch discovered that people did not only eat flower bulbs at that time, but also radish leaves and wild plants such as sorrel and chickweed.
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Light-activatable metallodrugs and metal-functionalized liposomes
Metal-containing molecules combine geometrical features and a reactivity that are inherently different from that of organic molecules. My research focuses on light-activatable metal-based anticancer drugs and metal-functionalized liposomes. Light is a very selective way to activate photosensitive drugs…
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Trump's trade war introducing unilateral trade tariffs violates treaty
Terminating the Trade Treaty between the US, Mexico and Canada, as Trump intends, violates the treaty and also has implications for labour law, says emeritus professor of international labour law, Paul van der Heijden, in Dutch newspaper ‘Het Financieele Dagblad’.
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The Picnic: A Dream of Freedom and the Collapse of the Iron Curtain
The gripping story of a collective passion for freedom that shook the world.
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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Unlocking Nature’s Pharmacy from Bogland Species
Development of Natural Resource for New Medicines
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Engineering of antigen-saving dissolving microneedles for intradermal vaccine delivery
The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.
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It's about time
This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.
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Corinna Jentzsch
Faculteit der Sociale Wetenschappen
c.jentzsch@fsw.leidenuniv.nl | +31 71 527 3456
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Bart van der Boom
Faculty of Humanities
b.e.van.der.boom@hum.leidenuniv.nl | +31 71 527 2762
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Giles Scott-Smith
Faculty Governance and Global Affairs
g.p.scott-smith@luc.leidenuniv.nl | +31 70 800 9503
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Claire Vergerio
Faculteit der Sociale Wetenschappen
c.vergerio@fsw.leidenuniv.nl | +31 71 527 2727
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Eamon Aloyo
Faculty Governance and Global Affairs
e.t.aloyo@fgga.leidenuniv.nl | +31 70 800 9195
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Catherine Wood
Faculty of Humanities
c.m.wood@hum.leidenuniv.nl | +31 71 527 7177
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Carolien Stolte
Faculty of Humanities
c.m.stolte@hum.leidenuniv.nl | +31 71 527 7308
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Call for Papers: Perceptions of Just War in the Middle Ages (IMC 2025)
The Research Training Group “Byzantium and the Euro-Mediterranean Cultures of War” invites scholars to submit paper proposals for a series of sessions on “Perceptions of Just War in the Middle Ages” at the IMC 2025. These sessions aim to explore the diverse theological, philosophical, legal, and cultural…
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Thijs Brocades Zaalberg: 'How does the discourse on war influence practice?'
As a student, Thijs Brocades Zaalberg was primarily interested in diplomacy surrounding conflicts. Through research on peace operations and subsequently the fight against guerrillas, he became increasingly involved with the most violent aspects of colonial warfare. Per 1 September 2024 he is appointed…
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Breakthrough by Leiden researchers in Pompe disease
Researchers at Leiden University have made a breakthrough in the study of the hereditary Pompe disease. Together with colleagues in York, they have developed a molecule that binds to the enzyme that is key to the progress of the disease. The findings have been published in ACS Central Science.
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…