The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…

Announcement of a new publication by Janneke Verheijen, lecturer at the Institute of Cultural Anthropology and Development Sociology.

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.

Electronic versions of our publications can be obtained by sending an e-mail to Esther van den Bos: bosejvanden@fsw.leidenuniv.nl

On 22 January 2020, Annemarie Madani-Abbing will defend her dissertation 'Art Therapy & Anxiety'.

Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

In the specialisation Child and Adolescent Psychology , part of the Master in Psychology, you develop practical skills in assessing and managing developmental psychopathology.

Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.

The Leiden University Medical Center (LUMC) will start construction this year of the largest non-profit stem cell and gene therapy facility in the Netherlands, and one of the largest facilities in Europe. NECSTGEN – the Netherlands Center for the Clinical Advancement of Stem Cell and Gene Therapies…

Light makes us flourish – in this respect we humans are just like a rose or an azalea. Light can also be used to treat people who are ill. In Leiden, Sylvestre Bonnet and Esther Habers are working – each in their own discipline – on new applications of light in a clinical context.

How do macrophages and neutrophils contribute to metastatic onset?

Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…

At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.

One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

How can zebrafish research help to understand and fight human cancer?

At Leiden University, researchers from all disciplines work together to find answers and design innovations in the field of artificial intelligence.

NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…

Key publications of the Quantitative Pharmacology group

The master's specialisation Health and Medical Psychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?

Research lines within the Pharmacy group:

Digital media are everywhere and are therefore a major part of our lives and the lives of our children. The new specialisation in Digital Media in Human Development focuses on the opportunities and challenges of digital media in child rearing and education.

We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.

In the specialisation Methodology and Statistics, part of the Master in Psychology, you will focus on in-depth study of statistical theory and research methodology as well as on the acquisition of data analysis skills.

Coordination chemistry is the chemistry of metal atoms

Regenerative medicine is a new way of treatment that helps impaired cells, tissues, and organs work well again. We do this by repairing, replacing, or restoring cells, tissues, and organs after damage from illness or injury. This includes treating long-term diseases such as diabetes, kidney diseases,…

Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.

Semiha Aydin is one of the three first-generation researchers who received a grant from the Leiden Empowerment Fund to stimulate their scientific career.

Proton therapy is a new way of treating cancer in which radiation doses are delivered more precisely. This results in less damage to surrounding tissue and fewer side effects. Professor Marco van Vulpen is medical director of HollandPTC in Delft, where the social value of this therapy is studied. Van…

Hans Ulrich Scherer is Professor of Rheumatology, in particular Translational Rheumatology. He wants to build bridges between research and clinical practice and between departments and organisations at home and abroad. Scherer will give his inaugural lecture next Friday. ‘To make progress, we have to…

In 2013, Sylvestre Bonnet received an ERC Starting Grant to kill cancer with molecules that can be activated by light. Two postdocs and three PhD students later, the end approaches of his so far successful project.

Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.

Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.

Four Leiden researchers have been awarded Proof of Concept grants by the ERC. These grants, each worth 150,000 euros, help researchers translate the findings of previous ERC projects into innovative practical applications.

Many primary school children suffer from anxiety and their numbers are increasing. Psychologists from the Knowledge Center Anxiety & Stress (KAS) are developing and researching preventive training.

Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).

Military veterans with posttraumatic stress disorder often have symptoms that are both chronic and complex. Professor by Special Appointment Eric Vermetten is looking for new ways to help them deal with these. One possible medicine: party drug MDMA.

Public funding for fundamental research is essential for innovation and the development of new medicines. This is demonstrated by Professor Science Based Business Simcha Jong and his colleague Hsini Huang after studying US federal funding restrictions for stem cell research under President George W.…

Bacteriophages, viruses that infect bacteria, may be used as an alternative treatment option when antibiotics fail. Leiden researchers have studied the structure and function of a novel bacteriophage that could be used to treat one of the WHO bacterial strains of concern where new treatments are urgently…

From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish