Life Sciences Artificial Intelligence Data Science

Tracing the residues of Neolithic activities through the study of stone artefacts

A novel in vivo model system for studies on glucocorticoid resistance

The goal of hit and lead optimization is to optimize suitable chemical starting points that can modulate a drug target. The methods and technologies used are similar to those in Hit Discovery, but once the compound has shown activity in an animal model, it moves from 'hit' to 'lead.'

Science, Leiden Institute of Physics (LION)

Science, Institute of Biology Leiden (IBL)

Studenten onderzochten maatschappelijke vraagstukken voor het project Leren met de Stad en presenteerden hun resultaten tijdens een informatiemarkt.

Your toddler refuses to eat vegetables, your child is being bullied at school, or you’re simply overwhelmed by everything on your plate. How can parents manage these situations effectively? During this Week of Parenting, our researchers and lecturers share practical advice for parents.

We are happy to announce the 3rd annual LION Image Award!

We are happy to announce the 4th annual LION Image Award!

Members of our research team give different types of presentations and lectures.

Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…

A new executive board has been installed at NeCEN, a state-of-the art facility that offers the most advanced cryo-electron microscopes worldwide. The new board members are full of excitement: what are their ideas for the future of the facility?

The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

A passion for video games, visuals and science: it almost seems impossible to bring all of this together. Yet, scientific animator Vera Williams found that dream combination at NeCEN's microscopy lab. 'An image or animation can help clarify the content of complex research.'

The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.

Five projects with researchers from Leiden University have received a grant from the Dutch Research Council (NWO) to build or upgrade existing research facilities.

Physicist Milan Allan will build an instrument that will bring superconductivity research further. He has been awarded an ERC Consolidator Grant of 2 million euros over the next five years. With his PairNoise programme he aims to detect paired electrons as they occur just above the temperature at which…

The coronavirus has the world in its grip. Finding a cure has never been more important. Unfortunately, the development of new drugs for treatment of the COVID-19 disease caused by the virus and development of a vaccine are complex, lengthy, and above all costly processes. With the help of computer…

De decentralisaties van de zorg aan langdurig zieken en ouderen, jeugdzorg, en werk en inkomen die vanaf 2015 zijn doorgevoerd in Nederland hebben geleid tot een transitie van een centraal naar een lokaal stelsel van zorg en welzijn. Deze transitie beoogt zorg en ondersteuning dichter bij de inwoners…

Last Monday April 18, Bram Koster (professor at the Institute of Biology Leiden (IBL), professor at the Leiden University Medical Center (LUMC)) and Ariane Briegel (professor at the IBL) gave a presentation to the mayor of Leiden, Henri Lenferink. The presentation took place at NeCEN, the open access…

On Monday 21 September Annemarie Meijer, Professor of Immunobiology, presented her inaugural lecture on immunobiology and infectious disease.

On April 20, sixty participants will take part in LION’s triannual meeting for high school physics teachers, to deepen their knowledge of physics and astronomy and to explore new teaching methods. This edition marks a special occasion, as it is the last meeting organized by Bert van der Hoorn, who will…

In 2021 we will start with a weekly lunch time seminar series, online on Mondays from 12 noon onwards.

The winner of the Paul & Tatiana Ehrenfest physics thesis prize 2020 is Koen Bastiaans. He carried out his PhD research in the group of Milan Allan and defended his thesis in December 2019 cum laude at Leiden University.

Mapping of bacterial genomes to combat infectious diseases

The European FET-Horizon2020 LMCat project of Dr. Irene Groot has released a promotional video showing the role graphene could play in our daily lives, how LMCat's production technique works, and how the consortium is capable of taking graphene production to the next level.

Cell-based medicinal products (CBMPs) belong to an innovative and heterogeneous group of medicines called advanced therapy medicinal products (ATMPs). The limited analytical toolbox for CBMP characterization and release testing is one of the reasons why CBMP development is so challenging.

Thomas Bakkum en Tom van der Wel, two PhD candidates from the Leiden Institute of Chemistry, have both won poster prizes at the EMBL Chemical Biology Conference 2018 in Heidelberg.

Current research at the Skin Barrier and Vaccination group.

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Relevant publications of the CIGR participants.

The doors of the new Gorlaeus Building are officially open! With an additional lab wing, new lecture halls and offices, a library, a brasserie, and spaces for student associations, the building offers a vibrant and inspiring environment for research, study, and social interaction. Explore on your…

Organ-on-chip technology is used in drug research and customized treatments for patients. Research Institutes and industry join forces within the Institute for human Organ and Disease Model Technologies (hDMT) that was officially launched on May 18. Combining facilities, people and expertise will allow…

From 22 to 24 October, researchers of the MARBLES-project informed museum visitors about microbes: bacteria and fungi that live all around us. The event was organised around the Micro-day of Leiden, which is this year’s EU City of Science.

Prof. Dr. Ir. Marin van Heel, Emeritus Professor at the Institute of Biology Leiden (NeCEN), is one of the winners of the “Wiley Prize in Biomedical Sciences 2017”. This annual award is presented to recognize contributions that have opened new fields of research or have advanced concepts in a particular…

The Dutch Research Council (NWO) has granted four grants to Leiden humanities scholars. They get to spend this money on research on a topic of their choice, without thematic preconditions.

Why are health problems such as loneliness and obesity so persistent? What causes them to occur more frequently in some neighborhoods than others? And how can we solve them? You will learn about these topics in the new minor 'Co-creating a Healthy Society'.

Three students in Elpine de Boer’s class “Practicing Religious Studies” have been working together on a “Leren met de Stad” (“Learning with the City”) project with community centre Morschwijck, located in Leiden. The students were asked by the organization Incluzio to investigate to which extent cultural…

The European Research Council (ERC) has awarded chemist Dr Alexander Kros a Starting Independent Researcher Grant of 1.4 million euro. He will be using the grant to study how molecules penetrate the natural barrier of a cell membrane. If his research is successful, it will in time bring about a revolution…

Eleven Leiden researchers have been awarded an 800,000 euro Vidi grant by the Dutch Research Council (NWO). This will enable them to develop their own innovative line of research and start their own research group.

Leiden Physicists have developed a new technique to visualize electrical conductance in sheet-like nano materials. It shows great promise for devices based on a new family of materials—the ‘Van der Waals materials’. The physicists, who won the 2015 Dutch Vacuum Society prize for their work, present…

We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.

He presented his PhD research entitled “Kick-starting drug development; translational systems pharmacology using innovative zebrafish experiments and advanced computational modelling”. During his presentation, Rob highlighted the advancements he made in using zebrafish as model in system pharmacolog…

As of 1 June, Leiden University has appointed Sense Jan van der Molen as Professor Physics of Condensed matter. He investigates the unique electronic properties that arise when atomic thin layers are stacked on top of each other into new materials.

Mysterious protein fibers show up in the brain cells of people suffering from Alzheimer’s' disease and other neurodegenerative disorders. Leiden physicist Louise Jawerth has been awarded a Vidi grant to find out how these fibers form in the first place.

The image of the Leiden microboat traveled all over the world, from the BBC up to Arab shipping blogs. But Daniela Kraft's research group has quite a few more different 3D printed microswimmers up their sleeves. Kraft receives a Vidi research grant for research into these variously shaped active par…

Why do some bacteria lose their protective cell wall under the influence of stress? Microbiologist Dennis Claessen of the Institute of Biology Leiden receives a Vici grant of 1.5 million euros from the Dutch Research Council (NWO) to investigate this paradoxical feature.