Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…

The fact that corona has created a wave of creativity is evident when walking around in the lab of pharmacologist Coen van Hasselt from the LACDR. Suddenly there were far fewer master's students permitted in the lab for their research. So Van Hasselt came up with smart solutions to enable lab work to…

Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…

On 26 November 1940 Professor Cleveringa held his courageous speech protesting against the dismissal of his Jewish colleague, Professor Meijers. Cleveringa was arrested and the university was closed. Every year the university honours Cleveringa with a chair and meetings throughout the world.

A COVID-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies is shown to provide good protection in a mouse model, Leiden University Medical Center (LUMC) researchers report in Nature Communications. According to them, the alternative vaccine may offer a…

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

The war in Ukraine has lasted almost two weeks now. What does Putin expect to achieve with his invasion and how big is the chance that the West will get involved? We phoned André Gerrits, professor and expert on Russia.

Within just a few years, the Chinese government's policy towards the Uyghurs deteriorated sharply. From control and marginalisation, it shifted to violation of human rights. PhD candidate Elke Spiessens was right in the middle of it with her research. 'The fabric of the community is being completely…

In cryptography, the sky is the limit according to the new professor Mathematical Cryptology Léo Ducas. He already designed several cryptosystems as part of his research at the Centrum Wiskunde & Informatica (CWI), some of which might soon be adopted as new international standards. Since December,…

During the LACDR Fall Symposium the Suzanne Hovinga Award for ‘best master thesis’ was awarded to Carlijn Lems for her master thesis entitled ‘Elucidating the crosstalk between epithelial-to-mesenchymal transition and Programmed Death-Ligand 1: validation and extension of a computational model’. Carlijn…

During the LACDR Fall Symposium, Niek Kijk in de Vegte received the annual Suzanne Hovinga Award for the best master thesis. Niek performed his RP1 research under the supervision of Dr. Natalia Ortiz Zacarias and Prof.dr. Laura Heitman in the Molecular Pharmacology group at the Division of Drug Discovery…

On Thursday the 9th of December the LACDR Fall Symposium 2021 took place. Although the plan was to organize this symposium physically, unfortunately this was not possible due to the corona measures and it became an online event.

PhD candidates Mohammed Saleh and Berfin Gülave (Division of Systems Pharmacology and Pharmacy) published their research paper on “Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice”.

Prof. dr. Douwe Breimer, emeritus Professor of Pharmacology, former Rector Magnificus and founder of LACDR has established a foundation to stimulate, support, and promote scientific meetings in the field of Pharmacology. Particularly those concerned with fundamental research and mathematical modelling…

On the 8th of March the first "introduction to entrepreneurship" boot camp was held at PLNT specifically for PhD researchers at the LACDR. During the two hour block topics such as "the core of entrepreneurship", "spotting opportunities" and "what is your value proposition" were discussed.

From self-driving cars to innovative drug development, artificial intelligence (AI) is going to fundamentally change our lives in a variety of ways.

Piercing through the skull with an ice pick, administering electric shocks without an anaesthetic, or applying leeches to the uterus: these may seem like medieval methods of torture, but they are in fact therapies used in medicine. Willem van der Does writes about all of them in his new book. ‘Physicians…

PhD defence

Suruchi Nepal, postdoc in the group of Coen van Hasselt at LACDR, was awarded an NWO XS project which aims to study the response to antibiotic treatment during a urinary tract infection (UTI). This knowledge will be used to determine how treatments of UTIs with antibiotics can be further improved.

Social media are playing a key role in calling for resistance to the corona measures. Online, agreements are made about where and when people will gather to protest. The authorities are not always fully aware of what is happening and cannot just infiltrate, whereas civilians can often easily participate…

Psychologist Ilse van de Groep found that people react more aggressively when receiving negative feedback. However, if people already exhibit persistent antisocial behavior they do not respond even more aggressively to negative feedback.This research earned her the Koningsheide Prize 2022 for the scientific…

The whole world is waiting anxiously for sufficient supplies of coronavirus vaccines. As Launch Navigator at Pfizer, alumnus Dennis de Mik must help ensure that the Netherlands receives 19.8 million doses of the Pfizer/BioNTech vaccine. How is he going about this and how has his Bio-Pharmaceutical Sciences…

Lecture, Online webinar

Symposium

Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?

What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'

Hans Ulrich Scherer is Professor of Rheumatology, in particular Translational Rheumatology. He wants to build bridges between research and clinical practice and between departments and organisations at home and abroad. Scherer will give his inaugural lecture next Friday. ‘To make progress, we have to…

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…

Inaugural lecture

Dr. Andrew Littlejohn has been awarded a Hunt Postdoctoral Fellowship by the Wenner-Gren Foundation for Anthropological Research. The fellowship provides funds for early-career scholars to write and publish significant monographs that will impact the development of anthropology.

Grabovski spoke in various media on the occasion of Holocaust Remembrance Day on 27 January 2022.

Education, Facility

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.

Soil that is too wet, or too dry. Or with a lot or few nutrients. Due to climate change, the differences are becoming bigger, and plants must increasingly be able to adapt to survive. How do you make plants more stress-resistant? For this purpose, researchers from Leiden, along with other universities,…

Students for Palestine – a group of students from Leiden and The Hague – are holding a panel discussion in the Leiden University in The Hague Wijnhaven building on Tuesday 24 May entitled ‘Silencing Palestine’.

Education, Research

Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.

When we think of unethical medical experiments, we tend to think first of Nazi Germany. What is less well known is that experiments were also carried out in colonised areas without the explicit consent of the test subject. University lecturer Fenneke Sysling has received a European grant to research…

Gerard van Westen has received the KNCV Gold Medal, the most important Dutch award for chemists under 40. 'It's a huge honour,' says the professor of AI and medicinal chemistry. 'I am now part of the group of people I was always impressed by.'

As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…

How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

On July 28, 2022, our dear colleague Daniëlle Hamstra passed away after a short sickbed. Daniëlle had been associated with the Clinical Psychology Section since 2010, initially as a student in the research master's program and subsequently as a lecturer and PhD candidate.

Last month, research by the National Institute for Public Health and the Environment (RIVM) revealed that more than half of students in higher professional education and at universities experience psychological complaints and emotional exhaustion, and that a quarter of them suffer from anhedonia (loss…

The steady decline in lethal gun violence in the EU came to halt in 2012 and some countries, such as Sweden, have even noticed an increase since then. An arms race among drug criminals and an increase in the availability of illegal firearms could lead to more criminal and gun violence. This is one of…

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.

The right medicine in the right dosage for every patient, that is something medical science aspires. 'Personalised medicine' is the term for that. But it does require a lot of research with patient data and that can be hard to get due to privacy legislation. Researchers Laura Zwep and Coen van Hasselt…