From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish

Late in 2015 a woman gave birth to a baby conceived following the reimplantation of thawed ovarian tissue. The woman was able to become pregnant thanks to transplantation of the tissue that took place in the LUMC.

Promotor: M. Ubbink, Co-promotor: G. Siegal

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

From time to time, manuscripts that have remained hidden for centuries turn up in library collections and archives. In the archives of the 17th-century Bibliotheca Thysiana at the Rapenburg in Leiden, kept in the Leiden University Library, Rotterdam researcher Erik-Jan Bos discovered a hitherto unknown…

With a 'Kiem grant' of up to €10,000, Leiden University stimulates initiatives in research and education where diverse fields of study meet. This interdisciplinary approach helps solve complex issues.

The British police discovered 39 bodies in the back of a lorry earlier this month. The refrigeration unit in which the bodies were found had entered the United Kingdom via Belgium.

The manner and context in which the government supports citizens' initiatives are often more important than the legal framework. In practice, it only creates unnecessary division and there are no solid grounds for it. Esmée Driessen, PhD candidate at the Department of Constitutional and Administrative…

Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.

One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.

Over 170 SUNRISE’s stakeholders gathered on June 17-18 at the Academy Palace of Brussels, in connection with the EU Sustainable Energy Week, as one of the Energy Days. Renewable energy experts from Academia, Industry and Policy addressed the current state of the initiative and its priority research…

Conference

Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’

The Van Bergen Fund aims to promote contacts between Dutch and international students in order to achieve a better understanding of each other's cultures. At the Symposium for Diversity and Inclusion the two winners of the Van Bergen Award 2015 were announced.

The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…

With cancer, the immune system is a double-edged sword: it can attack tumour cells, but can also help them grow and spread. It is a question of harnessing it. This is what Professor Karin de Visser argued in her inaugural lecture on 15 November 2019.

Can light-activatable ruthenium compounds be used as a more selective anticancer treatment?

Is it possible for sugar patterns on cells to activate the immune system to combat cancer?

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

PhD defence

How can zebrafish research help understanding human diseases?

An international team of researchers led by Alice Booth (Leiden University, the Netherlands) have discovered methanol in the warm part of a planet-forming disk. The methanol cannot have been produced there and must have originated in the cold gas clouds from which the star and the disk formed. Thus,…

The overall aim of CAM-PaC is to contribute to solving the socioeconomic and health challenges of PDAC by an integrative and systematic functional analysis of pancreatic cancer candidate genes. CAM-PaC will develop novel cellular and animal models, as well as novel strategies to analyse and integrate…

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

PhD defence

PhD defence

Previous OSCL events and member initiatives include:

In this work, we attempt to answer the question:

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

In January 2020, Marja Spierenburg joined the FSW as the new Professor of Anthropology of Sustainability and Livelihoods. Let’s get to know her. ‘All my research is basically about nature conservation. I look at areas like national parks, but also at measures aimed at increasing the sustainability of…

A month ago it was Marc Baggelaar, and now Hans Kistemaker too has obtained his PhD cum laude at the Leiden Institute for Chemistry (LIC). ‘He has made ground-breaking contributions to the world of protein modification,’ says PhD supervisor Gijs van der Marel. Kistemaker obtained his PhD on 11 May…

PhD student Janine Westendorp and her colleagues conducted literature research on what patients with cancer and their loved ones perceive as harmful communication from healthcare providers. The results were published in the journal Psycho-Oncology and are released as a poster to distribute to healthcare…

Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

Chemotherapy that does nothing until you irradiate it with light. Sylvestre Bonnet receives a Vici grant of 1.5 million euros for the development of this treatment. The Leiden chemist wants to build a new molecule to fight tumours that are at the time still difficult to treat.

Leiden has a long history in the treatment of blood cell cancer. Research to find better therapies never stands still. One of the potential treatments currently being worked on is a ‘living medicine’.

As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…

The Leiden Institute of Physics has been awarded three out of twelve available grants from the FOM Projectruimte. Principal Investigators Milan Allan, Stefan Semrau and Carlo Beenakker all receive around 400,000 euro for their research.

The National Bee Count initiative of Professor Koos Biesmeijer (Naturalis/Leiden) and Vincent Kalkman (Naturalis) has received the NWO Communication Initiative Award. The jury praises the initiative, which manages to reach a very wide and diverse audience, while at the same time contributing to the…

Treatment and care for cancer patients is becoming increasingly advanced. For example, surgeons can now perform operations with much greater precision, and therapeutic vaccines are being developed to prompt the patient’s immune system to fight cancer. Work is also being done on better early diagnostics,…

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

How can you do your bit for sustainability? Students from Leiden University have launched an interactive website with 150 sustainable initiatives in and around The Hague. The website Sustainable The Hague makes it easy to find a sustainable shop, restaurant or community initiative in your local area…

Former masterstudent Bio-Pharmaceutical Sciences Maddalena Centanni will be awarded the 2020 Arenberg Coimbra Prize for Erasmus Students. Centanni spent her six month Erasmus exchange at Uppsala Universiy in Sweden where she looked for ways to improve anti-cancer drug dosing.

PhD defence

Lecture

Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.

For present purposes, it is important to distinguish between an early period of settlement, about 6800-6200 BC, and a late period, about 6200-5800 BC, at Tell Sabi Abyad.

How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?