1,037 search results for “biological come” in the Public website
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The neurobiology of depression and the relation between stress, mental health, ageing and chronic illness
I want to understand the overlap between physical health, mental health, and healthy aging and whether/how stress (behaviorally and biologically) may tie these concepts together.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Research
Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.
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Patterns of Paleomobility in the Ancient Antilles
Patterns of paleomobility in the Caribbean were studied through an inter-disciplinary approach using a combination of archaeological, osteological, mortuary, and isotopic data.
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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ACTION
Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behaviour is seen. By combining interdisciplinary expertise the ACTION consortium…
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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In vitro and in vivo evaluation of synergistic and opposing effects of Chinese herbal medicine and natural compounds on immuno-modulation.
Can we link multiple components from herbal extracts with their biological activities?
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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LUECCM
The Leiden University-European Center for Chinese Medicine and Natural Compounds (LUECCM) is a virtual research Centre bringing together research projects of many different researchers from different origin.
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Making the invisible visible: paramagnetic NMR and the transient protein complex
Promotor: Prof.dr. M. Ubbink
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eV-TEM: Transmission Electron Microscopy with few-eV Electrons
Electron microscopy has become an extremely important techniquein a wide variety of elds.
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Integrating cellular and tissue dynamics with cell fate decisions through computational modeling
There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…
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Superstructures of lipids and graphene
This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Career prospects
Completing your Master’s in Biology gives you an internationally recognised degree which you can follow up with a PhD track. With your acquainted skills, you’re a much requested professional in and outside research.
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
- Molecular Biotechnology
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Human Evolution
This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…
- Pre-master's
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Programme structure
The programme offers you the ability to combine experimental research with theoretical courses. The programme helps you grow into an independent and skilled physicist.
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About the programme
The two-year Bioinformatics programme (120 EC) includes mandatory core courses and electives, as well as a Master's Thesis Research Project.
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Above- and belowground interactions in Jacobaea vulgaris: zooming in and zooming out from a plant-soil feedback perspective
In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…
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Leiden - Indonesia
Leiden University has a long tradition in the collaboration with Indonesia.
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Programme structure
The MSc program Evolutionary Biology focuses on important factors for the evolution of organisms. It prepares you for a research careers at universities, research institutes, or biotechnology sector. It’s also possible to combine training in biological research with training in communication, education…
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Man, woman and more: 'Why does my passport have to say I'm a woman?'
Protests against textbooks on trans persons in America and against a reading hour by drag queens in Rotterdam: it has been raining protests recently against people with a gender expression that does not match their birth sex. Why does this evoke such resistance? We asked Professor by special appointment…
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Our sixty-minute hour comes from Sumerian
Sumerian is a dead language that is not related to any other language. Howeverr, Bram Jagersma managed to compile a grammar of the language, based on inscriptions and clay tablets. Traces of the Sumerian number system can still be seen in our sixty-minute hour. Jagersma received his PhD on 4 Novembe…
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Coming this fall: Al-Babtain visiting professor Maribel Fierro
This fall, LUCIS will have the pleasure of welcoming Professor Maribel Fierro, Research Professor at the CSIC (Consejo Superior de Investigaciones Científicas, Madrid), to Leiden. She is the third Abdulaziz Saud Al-Babtain Cultural Foundation Visiting Professor in Arabic Culture at Leiden University…
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Coming this fall: Al-Babtain visiting professor Wadad Kadi
This fall, LUCIS will have the pleasure of welcoming Professor Wadad Kadi, of the University of Chicago, to Leiden. She is the first Abdulaziz Saud Al-Babtain Cultural Foundation Visiting Professor in Arabic Culture at Leiden University.
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Peter Rodrigues about the demands of municipalities when it comes to housing asylum seekers
Municipalities are becoming more and more selective when it comes to the nationality, age and sex of the asylum seekers they are willing to take in. This is the outcome of an investigation by Dutch newspaper NRC. And the Central Agency for the Reception of Asylum Seekers (COA) agrees with the results.…
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Gothic to OMG: the 21st conference on English historical linguistics comes to Leiden
The largest international conference on English historical linguistics is coming to Leiden. From 7 June to 11 June 2021, the Leiden University Centre for Linguistics (LUCL) organises the International Conference on English Historical Linguistics (ICEHL-21). Due to Covid measures, the conference takes…
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Online study
We bring science to your home! Join our online study called Biological Motion study!
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‘The new online teaching methods may also come in useful later’
Lecturers had a week to convert their courses to online teaching. An enormous challenge because remote teaching was definitely not commonplace at Leiden University. Professor of International Relations Madeleine Hosli’s students were just about to begin internships at international organisations in…
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Where does this Inca language come from? Verb conjugations should provide some answers
When university lecturer Martine Bruil was on exchange in Ecuador as a teenager, she fell in love with the area's ancient languages. Now, more than 20 years later, she is starting a research project on the kinship of the language Awapit with the Quechua language that was spread by the Incas.
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Journalists, online media professionals and researchers come together for second edition of MISDOOM
With over 200 participants, the first day of the Multidisciplinary International Symposium on Disinformation in Open Online Media (MISDOOM) was a great success. With researchers and practitioners from communication science, media studies, computer science, data science, and journalists and online media…
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Construction Day: Time to come and take a look in the University’s new Spui Building
You might be wondering what the reconstruction of the former V&D store at Spui in The Hague looks like now. If so, you can come and find out for yourself. On Saturday 8 June 2024, from 10.00 – 13.00 hrs., the building site of the new Campus The Hague Leiden University Building will be open to the pu…
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'Museums and opera houses will struggle for a long time to come'
The cultural sector, shut down by the corona pandemic, must urgently look for new ways to generate income.
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John Boy granted NWO XS for research Coming of Age on Instagram
Research often theorizes about young adults and their social media use. John Boy wants to investigate social media platforms by talking to users rather than talking about them
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Master’s Open Day: ‘I’ve mainly come to ask a lot of questions’
It was a soggy Friday, but the visitors to the Master's Open Day were made of sterner stuff. Bachelor's students from all around the world defied the rain and wind to take a look at Leiden and The Hague to find out more about master's programmes and to get to know the cities themselves.
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‘People can be expelled to countries that they don't come from'
The 'language analysis interview' on the basis of which the Immigration and Naturalisation Department attempts to determine where an asylum-seeker without any documents comes from, does not meet the criteria of reliability and validity. Joachim Detailleur, student of Arabic, substantiates this statement…
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Transvac2
TRANSVAC is a collaborative infrastructure project funded by the European Commission (EC), initially under the 7th Framework Programme (FP7) and currently under Horizon 2020. The project is a joint effort of leading European groups working in the field of vaccine development, and is coordinated by…
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Nietzsche's Philosophy of Conflict and the Logic of Organisational Struggle
A comprehensive analysis of Nietzsche's conception of conflict and the way in which relations of struggle condition the organisation of complex systems (with a specific focus on the human psyche and the body politic).
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Pushing the envelope of nuclear magnetic resonance spectroscopy for paramagnetic systems
A network combining 9 academic research groups and 4 collaborating industrial companies will train the next generation of PhD students and post-doctoral researchers, in developing and applying novel experimental and theoretical methods in the NMR spectroscopy of systems containing paramagnetic metals.…
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Research
Research at the BPOC/SSNMR group is comprised of the following research themes: