Research on this theme addresses the systemic risks faced by European societies and affecting the quality of life of European citizens.

Supervisor: Indira Nederpelt

Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

How is inflammation in tuberculosis controlled by interplay between autophagy and inflammasome signalling?

In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.

Work might not always be enjoyable, but what if just a glance at the to-do list brings on a sense of dread? To initiate the conversation about this, the sixth Psychology Connected focused on work pressure and workplace enjoyment, offering tips rooted in positive psychology.

Burnout is on the increase. It is caused by group pressure, being ‘on’ all the time and asking too much of ourselves. Clinical psychologist Bart Verkuil advises lowering our expectations.

Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

The LHSC booster grants awarded are described below. The summaries below are aimed at the general public. For further detail, please contact the researchers in question.

The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…

Hermelijn Smits is Professor of Host-commensal Interactions and Immune Modulation. In this role she is increasing our current understanding of the way in which microbes and parasites shape our immune system to protect us from respiratory infections and chronic inflammatory diseases. In her inaugural…

In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…

Development & Disease is one of the four research themes of the Institute of Biology Leiden.

The Faculty of Humanities' Justice, Equity, Diversity and Inclusion (JEDI) Fund provides small grants to initiatives in support of diversity and inclusion, with specific emphasis on creating an inclusive learning environment.

Lecture

The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).

Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

The aim of the RAISE study is to investigate how resilient people respond to stress. Specifically, we will study how key biological systems (HPA-axis, immune system) interact with the brain and social environment in order to facilitate resilient functioning after childhood adversities.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

Microbial Sciences' contribution to the Host-Microbe Interactions research theme is to investigate how beneficial or disease-causing microbes associate and interact with their host.

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

How do genetic and environmental factors make us vulnerable to depression?

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

This thesis examines the impacts and challenges of water use of electric power system. This thesis found that there are large differences in water use of electricity technologies, with hydropower and thermal power being two large water users.

This dissertation contains a detailed description of the Carib language, including the most extensive dictionary of the language to date. This knowledge is based on work from earlier sources and field work which was carried out by the author over a ten-year period, particularly in Galibi, a Carib village…

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

The research of the unit is aimed at the development of models to explain and describe the influences in social systems. Social influences are studied in three ways: from the perspective of group dynamics, from an individual-cognitive perspective, and from an economic and consumer psychological pers…

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

Zijn sociale aspecten van anxiety-like gedrag bij zeer jonge zebravissen al aanwezig? Zijn deze afhankelijk van de coping style (persoonlijkheid) van het individu? Zijn deze gedragingen endocrien te moduleren, bv door oxytocine?

‘Raising awareness of the disorder is crucial since borderline personality disorder (BPD) still faces considerable stigma ’, says Anne Krause-Utz (Clinical Psychology) . Together with an international team of excellent scientists, Krause-Utz provides an update of current knowledge about this disorder,…

Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.

Description of Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT) (2004 - 2007)

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This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.

The master's specialisation School Psychology consists of three main parts: the mandatory courses, the thesis and the internship/extra electives.

How effective is eye movement desensitization and reprocessing therapy in targeting epilepsy-related anxiety?

Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'

Three international research projects involving Leiden University researchers will receive funding from the Una Europa university alliance.

For the first time, research has been conducted on how the health of detained persons prior to their detention differs from that of non-detainees and to what extent health problems change over the period: from before and after their detention.

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Fitness is more than physical health alone. An equally important aspect of our general well-being is mental fitness. Mental fitness refers to the fitness of the mind. During your PhD research, there might be periods in which you feel insecure or down. It is essential to take good care of yourself. Don’t…

Are you interested in the neurocognitive and biological roots of learning, behaviour and emotions in children? If so, the programme in Applied Neuroscience in Human Development might be the specialisation you are looking for.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.

The ‘Leer te Durven!’ program (Learn to Dare) is a preventive training program for children with mild anxiety symptoms (Simon & Bögels, 2014). The program has been developed for children between the ages of 8 and 12 who feel or behave anxiously, avoid situations, are afraid of doing things wrong, appear…

Investigating specific language and speech behaviour of people.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

On the 21st of September, Carlos Benítez-Torres successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Carlos on this achievement!

Here we share findings into the effectiveness of the Designing Your Life education at Leiden University. Our study indicates that DYL education has a positive effect on students’ confidence and competencies.

Crafting Futures through Cheese-Making in Val Taleggio (Northern Italy) is written by Cristina Grasseni and is published in Gastronomica.