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Get to know us through our online and in-person event for prospective students!
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Information activities
Get to know us through our online and in-person events for prospective students!
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New light on dark matter
An international team of astronomers has found an unexpected link between dark matter and visible stars in stellar systems. This discovery may even cause us to reconsider our understanding of gravity. They published on their discovery in 'Nature' on 1 October.
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Immune Activation and Tolerance
The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…
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Online On Campus Master Experience Visual Ethnography
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Question of Conversion”: Internships in Work Package 3B of Pressing Matter
Pressing Matter: Ownership, Value and the Question of Colonial Heritage in Museums is a large-scale research project funded through the Dutch National Research Agenda, and led by Wayne Modest and Susan Legêne (Vrije Universiteit). Work Package 3 on “Value” phrases its main research question as follows:…
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Astronomers make invisible dark matter visible
An international team of astronomers, including Professor Koen Kuijken, has published a series of online articles presenting the first results of a major search for dark matter. Never before have researchers been able to chart so precisely the characteristics of groups of galaxies and their dark matter.…
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Fairness matters when responding to disasters: An experimental study of government legitimacy
This article by Honorata Mazepus and Florian van Leeuwen in the journal Governance: An International Journal of Policy, Administration and Institutions looks at how evaluations of authorities were influenced by four aspects of a governmental response to a hypothetical disaster.
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analytical approaches for protein aggregates and other particulate matter impurities
Developing robust and comprehensive analytical methods to size and quantify subvisible particles in biopharmaceutical products.
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Matter into context: population- and community-level impacts of nanomaterials in freshwater ecosystems
The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…
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Emotions in EU foreign policy - when and how do they matter?
Politicians' statements often involve emotions, shaping public perceptions. This study highlights the role of emotions in EU foreign policy.
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Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS
Activity-based protein profiling (ABPP) is a functional proteomics technique for directly monitoring the expression of active enzymes in cell extracts and living cells. The technique relies on irreversible inhibitors equipped with reactive groups (warheads) that covalently attach to the active site…
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Information activities
Get to know us through our online and in-person events for prospective students!
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Information activities
Get to know us through our online and in-person events for prospective students!
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Information activities
Get to know us through our online and in-person events for prospective students!
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Information activities
Get to know us through our online and in-person events for prospective students!
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Lexical Tone in Word Activation
On the 16th of May, Qing Yang successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Qing on this achievement!
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Social Science Matters: Housing
Students, first-time buyers, parents with stay-at-home children, migrants in need of a house; the problems in the housing market affect many layers within the society. The lack of housing is a growing problem. How does this affect our behaviour and the way we think about 'living' ? What are the consequences…
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Activity-based protein profiling of diacylglycerol lipases
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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The structure of the dusty cores of active galactic nuclei
Promotor: W. Jaffe, Co-promotor: K. Meisenheimer
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Social Science Matters: Internationalization
International education in the Netherlands is under pressure. There is pressure on the student housing market, and there is a greater desire among right-wing parties to keep our education and students within the borders and to make studies Dutch-language. In these social matters we look at what international…
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The Active Learning Network & Saltswat Pilot Program
2 joint initiatives began in 2019 which attempt to connect the various efforts around active learning at Leiden University: the active learning network, and the Saltswat project.
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Support with Active Learning & Teaching (SWAT)
You can get various forms of support for you active learning ambitions. Have you already reflected on your teaching practice and have a clear idea of your goals? Your first point of contact should then be your ICTO Coordinator & ICLON. Do you want to join the network of others involved in the topic?…
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African Activism at the UN
Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.
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Increased striatal activity in adolescence benefits learning
Heightened activation of the striatum that adolescents show in response to reward is often associated with risk-taking and negative health consequences. This article in Nature Communications investigates a potential positive side of this heightened activation. It shows that the activity peak in late…
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Spaces for Active Teaching and Learning (SALT)
Here you will find an overview of the Spaces for Active Teaching and Learning already implemented at Leiden University and LUMC. These rooms vary in size, location, material affordances, and technological affordances, and thus vary in the forms of pedagogy they best support. You can use this site as…
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Activity-based protein profiling of glucosidases, fucosidases and glucuronidases
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea
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Michel Orrit
Science
orrit@physics.leidenuniv.nl | +31 71 527 2727
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Dirk-Jan Kok
Science
d.d.kok@cml.leidenuniv.nl | +31 71 527 2727
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Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
- Kids Activities @ Middle Eastern Culture Market
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information activities MSc Cultural Anthropology and Development Sociology
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Social Science Matters: Wokeism
Minister of Justice Dilan Yeşilgöz-Zegerius recently warned against
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Register your output and activities in LUCRIS
Have you ever wondered how you can increase the visibility, accessibility, and recognition of your research while complying with funding and national requirements? LUCRIS is the answer!
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Fluorescence Polarization Activity-Based Protein Profiling on Retaining Glycosidases
Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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for good mental health during adolescence: Emotional Intelligence matters
In a longitudinal study, Eichengreen and colleagues explored how the certain aspects of emotional intelligence impact the development of adolescents’ mental health, thus identifying potential warning signs and targets for intervention programs. Despite a higher risk for mental health issues and lesser…
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Lecturing
The following lectures/courses are given in the framework of the EU Jean Monnet Chair EUTAXGOV at Leiden University. Topic of this Jean Monnet Chair: EU Tax Governance and International Tax Law Making by the EU.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Important Step for Dark Matter Experiment CERN
Particle lab CERN gives the green light for the test phase of an experiment that aims to produce dark matter particles. Physicist Alexey Boyarsky is one of the initiators.
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Information and activities, welcome to our Master!
Our Master’s Health, Ageing and Society can be your way to change the future! It gives you a fresh view on your personal future, and more in particular, on that of the future of elderly care. On this page you will find all the information you need to make your choice. One click is all it takes.
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Social Science Matters: Out-of-home placement
...What does seem clear, though, is that there is a great deal of room for improvement in the process of out-of-home placement. The FSW's social and behavioural scientists give their views.
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ERC Advanced Grant for dark matter research
Dark matter. Something invisible that, according to calculations, comprises about 85% of the matter in the universe. With an ERC Advanced Grant of €2.5 million, Professor of Observational Cosmology Henk Hoekstra will map out even more precisely where this dark matter is to be found.
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Social Science Matters: Open Science
On 20 September 2019, the opening drinks for the Open Science Community Leiden will be held at the Faculty of Social and Behavioural Sciences. Open science is the approach to science aimed at making scientific research accessible, reproducible, and freely available to people within and outside the academic…
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Geometry and Topology in Active and Driven Systems
The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).
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Social Science Matters: Online privacy
In our digital society, the internet seems to offer endless possibilities for expressing yourself, gathering information, and making contact with others. The anonymity of the internet seems to give us the freedom to come and go as we please. But what about our online privacy? Should it be dealt with…
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Social Science Matters: Climate change
Climate change is a hot topic and constantly in the news. Thousands of Dutch high school students protested at the Malieveld in The Hague. News website Nu.nl has barred climate change deniers from their comments section to prevent ‘fake news’. How does climate change impact the research community, and…
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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Social Science Matters: Confidence in the future?
After a long period of formation, the Rutte III cabinet presented itself on 26 October 2017. The coalition agreement on which ministers will build is called ‘Vertrouwen in de toekomst’ ('Confidence in the future'). But what impact will this new cabinet have on our future? We asked our researchers in…