Mateo Cohen (research assistant at the Open University of Israel and PhD candidate at Leiden University’s Institute of Political Science) studied arguments articulated by diverse members of the Right-Wing elite in Israel and explains how these views lead to the rejection of a two-state solution and…

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Microbial Sciences'contribution to the Development & Disease research theme is to perform world-class research to understand cellular morphogenesis, growth, development and virulence of microbes.

It is the dream of Professor Susana Chuva de Sousa Lopes to grow fertile egg cells in the lab. But she says there is a long way to go in her discipline until that is possible. This is the message of her inaugural lecture on 29 June 2020, the first digital inaugural lecture at Leiden University.

Zeynep Sarlak defended her thesis on 25 August 2020

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

This project aims at providing a broad perspective of the state of Science Technology and Innovation (STI) in Africa with a focus on global funding flows, in order to inform research funders in the continent, in particular those participating in the Science Granting Councils Initiative (SGCI). The project…

On 22 June, Najib Amin defended the thesis 'State-building, lawmaking, and criminal justice in Afghanistan: a case study of the prison system’s legal mandate, and the rehabilitation programmes in Pul-e-charkhi prison'. The doctoral research was supervised by Jan Michiel Otto and Pauline Schuyt.

Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they make these decisions is largely unknown. An international team of biophysicists…

The policies relating to language pursued by European monarchies and states have been widely studied, but far less attention has been given to their linguistic and cultural policies in territories outside their own borders.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

This edited volume provides a synthesis on the question of business attitudes towards and its influence over the development of the modern welfare state. It gathers leading scholars in the field to offer both in-depth historical country case studies and comparative chapters that discuss contemporary…

Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…

The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.

Leiden chemists, together with colleagues at the University of York (UK) and Technion (Israel) have discovered a small, sugar-like molecule that maintains the integrity of tissue around a tumour during cancer. This molecule prevents tumour cells from spreading from the primary cancer site to colonise…

Our focus is to optimize the fungal cell wall to both increase chitin production and chitin extractability.

Leiden physicists are helping Wageningen plant researchers to study unpredictable plant embryos. For this, they are using a novel two-photon fluorescence microscope, aided by a 30 thousand euro ZonMW grant.

Dennis Claessen has been appointed professor of Molecular Microbiology at the Institute of Biology Leiden. With his teaching and research on the cell wall, the professor wants to establish applications in the industry and the medical sector.

When the immune system attacks cancer, the tumour modifies itself to escape the immune reaction. Researchers at LUMC published on this subject in Nature on 28 June.

Advancing the understanding of the interaction of light and matter on the single-quantum level is important for near-future quantum technologies but also to answer fundamental questions.

The research project ‘The History of National Security, 1945-present', is funded by the Netherlands Organisation for Scientific Research (NWO), the Campus The Hague/Leiden University and the Netherlands Institute for Military History (NIMH). The project will run until the summer of 2013, when we hope…

Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager

Theoretical physicist Luca Giomi receives a 2 million euro ERC Consolidator Grant for research into flowing cells in a strange hexatic phase, which is half fluid, half solid.

An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…

The European Union has invested ten million euros in the so-called iNEXT-Discovery consortium. The goal of this new consortium is to enable European researchers to extend innovative structural biology research. The Netherlands Centre for Electron Nanoscopy (NeCEN) is also part of iNEXT-Disovery, which…

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

The transition from single cells to multicellular organisms was a key step in evolution. Researchers from Leiden and Amsterdam developed a mathematical model that explains how this transition may have come about. They suspect cooperating cells may correct each other’s mistakes. Publication in eLife…

On 23 April 2021, Professor Alfred Vertegaal from the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Unraveling and exploiting cellular communication codes’. Vertegaal used the opportunity to describe how research in the field…

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

Leiden biophysicist Stefan Semrau was granted an NWO Vidi earlier this month. He will use the grant to study the role of electricity in embryonic development and tissue regeneration.

Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…

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