3,332 search results for “parkinson s disease” in the Public website
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The role of auxin in somatic embryogenesis
What is the role of auxin in the initiation and process of somatic embryogenesis?
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Roeland Merks
Science
merksrmh@math.leidenuniv.nl | +31 71 527 7106
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Patrick van Hage
Science
p.van.hage@biology.leidenuniv.nl | +31 71 527 4950
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Maria Yazdanbakhsh
Faculteit Geneeskunde
m.yazdanbakhsh@lumc.nl | +31 71 526 5067
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Tuomas Aivelo
Science
t.j.e.aivelo@biology.leidenuniv.nl | +31 71 527 2727
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Coen van Hasselt
Science
coen.vanhasselt@lacdr.leidenuniv.nl | +31 71 527 3266
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Jordy van der Beek
Science
j.g.van.der.beek@cml.leidenuniv.nl | 071 5272727
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Joey Zuijdervelt
Science
j.l.zuijdervelt@lacdr.leidenuniv.nl | +31 71 527 6227
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Inflammafish: Cross-talk between inflammation and autophagy in tuberculosis
Effective host defence against tuberculosis bacteria depends on a properly balanced level of inflammation. The Inflammafish project uses zebrafish larvae to study how autophagy controls this inflammation and vice versa.
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Cryo-EM of cholera infection
The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?
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Lucy Opoka
Faculteit Rechtsgeleerdheid
l.a.opoka@law.leidenuniv.nl | +31 71 527 6438
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Katrien Klep
Faculteit Rechtsgeleerdheid
k.f.m.klep@law.leidenuniv.nl | +31 71 527 1325
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Ann Skelton
Faculteit Rechtsgeleerdheid
a.m.skelton@law.leidenuniv.nl | +31 71 527 2727
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Marijana Vujosevic
Faculty of Humanities
m.vujosevic@hum.leidenuniv.nl | +31 71 527 2727
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Jessie Pool
Faculteit Rechtsgeleerdheid
j.m.w.pool@law.leidenuniv.nl | +31 71 527 4035
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Mariëlle Bruning
Faculteit Rechtsgeleerdheid
m.r.bruning@law.leidenuniv.nl | +31 71 527 8913
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Jonathan Powell
Faculty of Humanities
j.d.powell@hum.leidenuniv.nl | +31 71 527 5586
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Sophy Baird
Faculteit Rechtsgeleerdheid
s.b.baird@law.leidenuniv.nl | 071 5272727
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Ton Liefaard
Faculteit Rechtsgeleerdheid
t.liefaard@law.leidenuniv.nl | +31 71 527 2727
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Maëlle Picout
Faculteit Rechtsgeleerdheid
m.j.picout@law.leidenuniv.nl | +31 71 527 2727
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Nitric oxide in defence against mycobacterial infection
Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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ZonMw Medical Inspirator Prize for research ‘Lyme paralyses lives’
Together with patient representatives, clinician-researchers from Radboucumc (Internal Medicine) Amsterdam UMC and researchers from Leiden University (Andrea Evers and Henriët van Middendorp) have received the Medical Inspirator Prize 2019 of The Netherlands Organisation for Health Research and Development…
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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Macrophage activation and cholesterol accumulation in atherosclerosis development
Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck
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SKY HIGH: Vertical farming a revolution in plant production
As a new vision on food production, the feasibility study on LED light to grow crops with the biological- and chemical evaluation of final products.
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Marker assisted breeding for thrips resistance in tomato
Which plant leaf characteristics are involved in thrips resistance in tomato?
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Richard Karlsson Linnér: ‘I expect a future where a genetic test will be as much a no-brainer as getting X-rayed.’
Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.
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Frits Rosendaal
Faculteit Geneeskunde
f.r.rosendaal@lumc.nl | +31 71 526 4037
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Annemarie Meijer
Science
a.h.meijer@biology.leidenuniv.nl | +31 71 527 4927
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ImageInLife: Training European experts in multilevel bioimaging, analysis and modelling of vertebrate development
How can novel bioimaging technologies and vertebrate model species be used to gain a better understanding of early cellular behaviours with the ultimate goal to increase our understanding of human development and disease processes?
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Mirjam Sombroek-van Doorm
Faculteit Rechtsgeleerdheid
m.p.sombroek@law.leidenuniv.nl | +31 71 527 2727
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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Biological and Soft Matter Physics
Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.
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Teeth Tell Tales
A multi-disciplinary approach to past lifestyles and cultural practices
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Chemokine signaling in Tuberculosis and Salmonella infection
Who benefits from CXCR/CXCL chemokine signaling during infection: host or pathogen?
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Live or let die: the intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Zebrafish: a new engraft model to study Ewing sarcoma progression
Can zebrafish provide a fast, sensitive in vivo vertebrate model for identifying novel mechanisms of Ewing sarcoma progression and for development of new anticancer compounds in a time- and cost-effective manner?
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Conquering the fortress: New strategies for the treatment of tuberculosis
Can we exploit the cell death machinery of the host to develop new host-directed anti-TB treatments?
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The serosa: an evolutionary novelty in insect eggs
What is the function of the insect serosa?
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‘Seeing voices’: the role of multimodal cues in vocal learning
Can birds - like people- ‘see’ voices and learn how to sing by listening and watching?
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Targeted biomolecule production for therapeutic use
We aim to develop a drug-delivery method based on the production of biomolecules directly at the target site.
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MeRGeR: Physiological significance of the glucocorticoid and mineralocorticoid receptor signaling in the innate immune system
Does the mineralocorticoid receptor play a role in the effects of cortisol and synthetic glucocorticoids on the immune response?