1,045 search results for “drie safety” in the Public website
-
Service desk Pieter de la Court
Pieter de la Court, Wassenaarseweg 52, 2333 AK, Leiden
-
Advanced in vitro models for studying drug induced toxicity
Promotor: Prof.dr. B. van de Water, Co-promotor: L.S. Price
-
Service desk KOG
Kamerlingh Onnes Building, Steenschuur 25, 2311 ES, Leiden
-
A large-scale crop protection bioassay data set
ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.
-
Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
-
Animal models for cutaneous vaccine delivery
Main challenges in skin vaccination are overcoming the stratum corneum (SC) barrier and targeting the antigen presenting cells (APC) in the epidermis and the dermis.
-
Combatting infectious diseases; nanotechnology as a platform for rational vaccine design
Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.
-
Pharmacogenomics in drug development: implementation and application of PKPD model based approaches
Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh
-
Drug research
In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.
-
Strategic Interaction of Governments and Terrorist Groups in Times of Economic Hardship
In this article, Tokdemir & Klein examine the strategic actions of governments against domestic terrorist groups and domestic terrorist groups’ reactions to such actions.
-
Jimpitan in Wonosobo, Central Java: an indigenous institution in the context of sustainable socio-economic development in Indonesia
In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.
-
Optimization of Patient Flow through EMT Facilities Applying Dynamic Behavioral Simulation Models
This study aims to explore the use of a behavioral-design-based approach in simulating patient flow through EMTs. It provides a dynamic behavioral simulation model to assess the interactions between patients, staff members, and the related dynamic movements/interactions with the health care facility,…
-
Spectral imaging and tomographic reconstruction methods for industrial applications
Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.
-
Teris van Beek
Dr. at the Department of organic chemistry, Wageningen University - the Nederlands
-
Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
-
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
-
Chemical Similarity: Structuring Risk and Hazard Assessment
At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.
-
Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
- Urban Studies
-
Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
-
Study programme
The PML specialisation prepares you with knowledge and understanding of the key concepts and theories of management, leadership, decision-making and policy implementation in national and international government organizations.
-
Career prospects
After graduation you have a lot of opportunities: academics are highly sought after in Dutch secondary education or mbo teaching. You can also aim for a management position or work as a researcher within the field of Life Sciences.
-
Servicedesk W&N
Gorlaeus Building, Einsteinweg 55, 2333 CC, Leiden
-
Get to know Security Studies
Terrorism, cybercrime, natural disasters and other issues affect the security and safety of millions each day. In Security Studies you learn to unravel security challenges by focusing on the political, historical and societal context in which they arise, as well as the effect of governance, institutions,…
-
Get to know Urban Studies
Cities are more relevant than ever. They play an increasingly important role in the issues of this time: climate change, inequality, safety and health. Our Urban Studies programme gives you the opportunity to be a problem solver, teaching you how to develop real-life answers to today’s and tomorrow’s…
-
Get to know Security Studies
Terrorism, cybercrime, natural disasters and other issues affect the security and safety of millions each day. In Security Studies you learn to unravel security challenges by focusing on the political, historical and societal context in which they arise, as well as the effect of governance, institutions,…
-
Get to know Urban Studies
Cities are more relevant than ever. They play an increasingly important role in the issues of this time: climate change, inequality, safety and health. Our Urban Studies programme gives you the opportunity to be a problem solver, teaching you how to develop real-life answers to today’s and tomorrow’s…
-
Organisation
Organisation of the Leiden Institute of Physics.
-
High attendance at Kirchheiner Conference on ‘The Ombudsman & the Rule of Law’
On Thursday 29 August 2024, Leiden University hosted the conference on theme of ‘The Ombudsman & the Rule of Law’. More than 100 participants from professional practice and academia attended the conference, which was organised by Professor Luc Verhey and Fatma Çapkurt from the Department of Constitutional…
-
Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
-
Career prospects
In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.
-
Gert Jan Geertjes defends preliminary advice Nederlandse Vereniging voor Wetgeving
At the annual conference of the Nederlandse Vereniging voor Wetgeving (the Dutch association for legislation) that was held in the Auditorium of the Ministries of Internal Affairs and Kingdom Relations and Justice and Security in The Hague on Thursday 6 October, Gert Jan Geertjens defended the draft…
-
Graig Klein awarded an ERC Starting Grant
Graig Klein, assistant professor at the Institute of Security of Global Affairs (ISGA), has been awarded a Starting Grant by the European Research Council (ERC) for his project TERGAP. With this 1.500.000 euro grant Klein and his research team will investigate terrorist groups’ decision-making and strategic…
-
‘International isolation is not an option’
Security in the broadest sense of the word was the key focus in the Interfaculty Conference on 4 April in Leiden. With almost 200 attendees and such well-known speakers as Dick Schoof, Pieter van Vollenhoven and Ad Verbrugge, the first conference was a success.
-
eLaw publishes self-assessment tool on age assurance for the European Commission
Simone van der Hof, Professor of Law and Digital Technologies at eLaw, and Mohammed Raiz Shaffique, researcher and PhD candidate at eLaw, have published a self-assessment tool on age assurance for the European Commission.
-
Essays on wealth, health, and data collection
On 21 November 2018, Lieke Kools defended her thesis 'Essays on wealth, health, and data collection'. The doctoral research was supervised by Prof. dr. K.P. Goudswaard en Prof. dr. C.L.J. Caminada.
-
Diplomacy at Leiden University
The Hague Journal of Diplomacy is hosted by the Institute of Security and Global Affairs at Leiden University. Besides the journal, there are many other activities related to diplomacy.
-
Multi-objective Evolutionary Algorithms for Optimal Scheduling
Multi-objective optimization is an effective technique for finding optimal solutions that balance several conflicting objectives. It has been applied in many fields of our world, because practical problems usually have more than one desired goal. For example, developing a new vehicle component might…
-
Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
-
Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
-
SCALES project
How to strike a balance between the sometimes conflicting stakes of individual, public and private data-producers and data-processors?
-
Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
-
Discoveries in 2023
From nanoparticles to colliding ice planets and from biological origami to new x-ray scanner techniques: this year again, our scientists have made wonderful discoveries. From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, take a look at each institute's…
-
Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
-
Development of Cost efficient Advanced DNA-based methods for specific Traceability issues and High Level On-site applications
Schneider
-
Host community compensation
Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?
-
Gendered impacts of industrial logging
This study focuses on the local level impacts of a highly globalised industry: the international trade in tropical timber.
-
Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems
On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.
-
Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation
Poly(lactic-co-glycolic acid) (PLGA) particles have been extensively studied as biodegradable delivery system to improve the potency and safety of protein-based vaccines. In this study we analyzed how the size of PLGA particles, and hence their ability to be engulfed by dendritic cells (DC), affects…
-
Focal Areas
Our research at CWTS is organized in three focal areas. These focal areas represent our core areas of interest, as defined in our knowledge agenda for the period 2023-2028.