Engagement between Asia and Europe is increasing. If these continents want to build a lasting relationship, they need to understand each other better in the economic, socio-cultural, historical and legal arena. Researchers from Leiden have already contributed to the body of knowledge on past and present…

Our team consists of the following members.

PhD defence

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

The MicroSOS project is designed to bring together academic and industrial partners with different expertises to address challenges that agriculture is facing due to climate change and invests in the development of microbiome-based solutions towards more sustainable agricultural practices.

Psycho-physiological reactions to stress.

From basic science to real-world interventions

Atherosclerosis is a chronic inflammatory disease, and vaccination may be an attractive method to induce long lasting protection against endogenous factors that contribute to the development of atherosclerosis. We have shown that for example vaccination against modified LDL or interleukin-12 limits…

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

The Resilience Center Leiden investigates how stress impacts the mental health of young people. For that, the team studies a multitude of factors, such as childhood experiences, the social environment, psychological factors, and neurobiological factors. With this multidimensional approach, we aim to…

Towards Health and Resilience in Volatile Environments - People differ in how they are impacted by and respond to stressful experiences. Why is that?

Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax

Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

Promotor: Prof.dr. B. van de Water, Co-promotores: J.W. van der Laan, C.L.E. Siezen

Both psoriasis and atheroslcerosis are diseases characterized by a chronic and systemic inflammatory profile with local lipid disturbances that alter the barrier function of the skin (psoriasis) and cause the development of atherosclerotic plaques (atherosclerosis).

Key publications of the Analytical BioSciences and Metabolomics group

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Cardiovascular disease is the leading cause of death worldwide.

Cardiovascular syndromes are the major cause of death in Western societies.

Occupational health in the Emergency Department

PhD defence

Empathic or anxious mistakes? A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

Making public space more sustainable is considered very important in this project. The Humanities Campus will become a pleasant place to spend time, with lots of greenery. Here, people can relax and find coolness on hot summer days.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…

How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…

Evidence that the right diet can prevent or alleviate depression is weak. In literature reviews on the subject, the authors often reach strong conclusions, nonetheless. This is what Florian Thomas-Odenthal, a master’s student in Psychology at Leiden University, discovered in his thesis research. Publication…

Knowledge of mental distress and resilience factors over the time span from before to after a stressor is important to be able to leverage the most promising resilience factors and promote mental health at the right time. To shed light on this topic, we designed the RESIST Study, in which we assessed…

Although the world has made tremendous progress in health, education, sanitation and hygiene, global public health challenges still exist. Disparities in health exist between and within nations as evidenced by inequalities in disease burden, mortality, nutrition and environmental well-being. How does…

The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…

My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?

What is the neurocognitive structure of human navigation ability? What different types of navigation impairment can be distinguished? How can navigation impairment best be diagnosed and treated? How can tools like serious gaming and virtual reality be used to diagnose and treat navigation impairment…

The aim of our research program is to better understand the etiology and course of mood, anxiety and stress-related disorders, such as depression and posttraumatic stress disorder (PTSD). We investigate both the transdiagnostic mechanisms underlying these disorders and work on improving the treatments…

To study relationships between emotion regulation after negative and traumatic life events and psychopathology. Within this context, another goal is to develop and validate emotion regulation questionnaires.

The Master’s programme Health, Ageing and Society trains its students to become academic Health, Ageing and Society professionals and engaged citizens who are competent and trained internationally and interdisciplinary. They are able to contribute to solutions for the challenges facing our ageing so…

Tijmen Baarda defended his PhD thesis on 8 January 2020

Is EEG theta\beta ratio predictive towards the negative effects of stress on cognitive performance in individuals suffering from performance anxiety? Can we improve resilience to performance anxiety by using a theta\beta ratio neurofeedback intervention?

You can find some tips here on how to maintain your mental health.

Promotor: W. Jiskoot, Co-promotor: A. Hawe

The focal point of the E&G specialisation is welfare states and markets. You develop your skills in economic reasoning, and conducting economic analysis, while learning about the role of government in creating, facilitating and controlling markets.

In the Public Management and Leadership specialisation within the Public Administation master's programme, you study such core themes as: leadership behavior in public organizations; decision-making by political leaders and top-level civil servants; and the changing interactions between government and…

Research into the evolutionary backgrounds of our diets can help us make the right choices in diet, health and lifestyle.

Source: Mediators Inflamm (2014)