1,909 search results for “mechanisms metamaterials” in the Public website
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Searching for an explanation for remarkable behaviour of ice on Earth
If you replace the standard hydrogen atoms in ice with a heavier variant, something odd happens. The volume occupied by the molecules increases by 0.1 per cent. Leiden chemist Jörg Meyer and his colleagues have created a theoretical model that describes this behaviour. Their research appeared on the…
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A glimpse into my research between Bayesian Optimization and Mechanics
Lecture
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Vibration Isolation
To be able to measure small forces or small deviations from Boltzmann, the external vibrations at the resonance frequency must be very low. To achieve this, we have developed a very soft vibration isolation system and combine it with several other measures to reduce vibrations in our dilution refrigerators.…
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The role of expectancies and avoidance learning in the maintenance of somatic symptoms
Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.
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Development & Disease in Plant Sciences
Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…
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Research
The aim of the research programme is to provide insight into the cognitive processes and brain mechanisms that underlie reading, arithmetic and learning in general.
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Banking Regulation in and for Crisis
In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, and Martin Lodge address the question of how to manage banking crises, a question that has gained prominence since the banking crisis of 2007-2009. This article sets out the rationale for regulating for…
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Cultural evolutionary modeling of patterns in language change. Exercises in evolutionary linguistics
This thesis describes the use of the evolutionary approach in the study of language change, aiming to provide a better insight in the mechanisms that play a role in language change and to validate this approach in the field of language change.
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Imaging of biomaterial-associated inflammation and infection using zebrafish
Which immune mechanisms are involved in host defense against Staphylococcal infection?
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In shape for photoregulation
How does the photoregulation mechanism work in detail?
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Transnational and Cross-Cultural Agents in the 17th Century Overseas Expansion
Why is Crossnational and Cross-cultural agents such as Henrich Carloff and Willem Leyel important when studying Early Modern expansion?
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Electroreduction of nitrate and carbon dioxide on copper electrodes: a mechanistic study
In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…
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The Lead Zeppelin
As an alternative to the diving board shaped force sensor, we are now developing a magnetically levitated small superconducting particle – or ‘Lead Zeppelin'' – as our mechanical resonator. We explore routes towards detection of gravity between small objects.
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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A study on PsbS and its role as a pH sensor
Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.
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‘Non-Istanbulites’ of Istanbul: Quest for a place in Istanbul in the Turkish novel since the 1960s
This research focuses on a historical/social analysis of a selected corpus of novels from modern Turkish literature which have the common theme of migration from Anatolian towns and villages to Istanbul, and the immigrants’ struggle in this city against various exclusion mechanisms.
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Role of integrin adhesions in cellular mechanotransduction
Promotor: B. vd Water, T. Schmidt, Co-Promotor: E.H.J. Danen
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Deciphering the complex paramagnetic NMR spectra of small laccase
Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.
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Zipping into Fusion
Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros
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Computational modeling of angiogenesis: from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Regulation and ICT
How does the development of digital technologies impact society, and law/regulation within that society?
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Photocatalytic redox reactions at the surface of liposomes
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman
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Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
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Social Feedback and Emotion Regulation in Borderline Personality Disorder: An fMRI study
What is the role of emotion regulation in coping with interpersonal feedback?
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Industrial Ecology
The research programme Industrial Ecology aims to support the ecological transformation of society and environment towards sustainability. The research subject is Industrial Ecology in its broadest definition, covering environmental systems analysis, and incorporating the social and economic aspects…
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When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn
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The stochastic geometry of non-Gaussian fields
Promotor: V. Vitelli, Co-promotor: J. Paulose
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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R-QUEST – Centre for Research Quality and Policy Impact Studies
The Centre for Research Quality and Policy Impact Studies (R-QUEST), which is funded by the RCN FORINNPOL initiative, is an 8-year commitment of several partners to explore the nature and mechanisms of research quality.
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Research
Industrial Ecology
- Leiden Academic Centre for Drug Research
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Perception of multidimensional speech sounds in humans and songbirds
Do humans and zebra finches share cognitive mechanisms that are important for speech perception?
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The Radicalization of the Left in Turkey and Iran in the 1970s and a Comparative Analysis the Activist Women's Experiences
Sevil Cakir-Kilincoglu defended her thesis on 18 December 2019
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Aspects of cosmic acceleration
The focus of the dissertation
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Design and synthesis of metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
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Laser-generated toroidal helium plasmas
This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.
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Next generation bacitracin: reimagining a classic antibiotic
Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…
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Education
The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.
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Risky Business?
Behavioral and neural mechanisms underlying risky decision-making in adolescents
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Bhattacharyya Lab - Quantum transport in 2D materials
The research group of Semonti Bhattacharyya at the Leiden Institute of Physics studies quantum transport measurements in Van der Waals heterostructures.
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Tapping into Semantic Recovery
On May 31st, Bobby Ruijgrok succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Bobby on this great result.
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Modelling the interactions of advanced micro- and nanoparticles with novel entities
Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Substrate adaptability of β-lactamase
The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…
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On the geometry of fracture and frustration
Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli