998 search results for “immuniteit infection en tolerance” in the Public website
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NWO Open Competition funding for three humanities scholars
Manon van der Heijden and Leo Lucassen, and Maarten Mous will receive NWO Open Competition funding. This funding amounts to a maximum of 750,000 euros and is intended to carry out research into a subject of their your own choice, without thematic preconditions.
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En de nieuwe assessor is...?
De studentassessor: één student die als lid van het faculteitsbestuur aanschuift bij alle belangrijke overleggen en projecten. Zo wordt de student, een van de belangrijkste doelgroepen, vertegenwoordigd bij bestuurlijke besluitvorming. Assessor Julie Külsen draagt volgend collegejaar per 1 september…
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Ton Koopman Huizinga Lecture 2016 ‘Bach en zijn zangers’
On December 9, 2016 Prof.dr. Ton Koopman will give a lecture 'Bach en zijn zangers' in the Pieterskerk in Leiden.
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Meijersprijzen en scriptieprijzen uitgereikt tijdens nieuwjaarsreceptie
Op dinsdag 10 januari 2022 zijn tijdens de facultaire nieuwjaarsreceptie de jaarlijkse Meijersprijzen en de scriptieprijzen uitgereikt.
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Duurzaamheidsverslag besproken in het symposium Duurzaamheid en Ondernemingsrecht
Onlangs organiseerde de afdeling Ondernemingsrecht in samenwerking met het tijdschrift Onderneming en Financiering het symposium Duurzaamheid en Ondernemingsrecht. De opkomst was een bevlogen groep juristen en ondernemers met hart voor het onderwerp.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Leiderschap voor gezonde en duurzame voedselomgeving zaak van lange adem
Despite the reduced accessibility as a result of the protests of the farmers in The Hague, around 30 directors, scientists, students and civil servants met on 16 October for the Public Leadership Challenge
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Spreading the Fire: Why is Pyroptotic Cell Death Contagious?
The word ¨pyroptosis¨ can be understood as ¨fiery falling¨, which describes the bursting of pro-inflammatory signals from the dying cell. Our observations indicate that pyroptosis also ¨spreads like wildfire¨ and once a cell dies via pyroptotic cell death, neighbouring cells are more prone to die as…
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Insights from modeling metabolism and amoeboid cell motility in the immune system
This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Systems vaccinology: molecular signatures of immunity to Bordetella pertussis
Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz
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Smartmix: A new generation of efficient biomedical research
Can we find and commercialise new treatments for chronic disease that affect our ageing population? And how can we customise this research and development programme to the small but highly-developed Netherlands research economy?
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Eredoctoraten voor Bonnie Honig, Eliot Higgins en Kelly Chibale
Leiden University will be conferring three honorary doctorates in its special anniversary year. They will be awarded to Eliot Higgins, truth finder and founder of Bellingcat, Bonnie Honig, expert in feminist theory and legal theory, and Kelly Chibale, professor of organic chemistry, who works on prevention…
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Staphylococcus aureus colonization and infection
PhD defence
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RESTORING T-CELL HOMEOSTASIS BY IN VIVO MANIPULATION OF DENDRITIC CELLS
The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Conferencia de la Prof.dr. Sayak Valencia en el X Congreso Internacional de la AHBx
El viernes 3 de noviembre a las 11.15 tendremos el gusto y honor de escuchar a la Prof.dr. Sayak Valencia en el marco del X Congreso Internacional de la AHBx. Prof.dr. Sayak Valencia (Tijuana, Mexico, 1980) impartirá la segunda conferencia plenaria del X Congreso Internacional de la AHBx bajo el título:…
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Mycobacterial cell wall-deficiency and its role in the persistence of tuberculosis
What is the role of cell wall-deficiency in the persistence of tuberculosis?
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Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
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Immunoproteomic Profiling of Bordetella pertussis Outer Membrane Vesicle Vaccine Reveals Broad and Balanced Humoral Immunogenicity
The current resurgence of whooping cough is alarming, and improved pertussis vaccines are thought to offer a solution. Outer membrane vesicle vaccines (omvPV) are potential vaccine candidates, but omvPV-induced humoral responses have not yet been characterized in detail.
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Second ILS Lunch Seminar with Dr. Cuyvers en Dr. Broekhuijsen
After the kick-off on 28 November, the next ILS Lunch Seminar will take place on Monday 19 December. During this lunch seminar series all researchers from Leiden Law School can present their research. The idea is to hear in a simple and nice way what researchers from other research programs and institutes…
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Glucocorticoid modulation of the immune response
Unraveling the immune-suppressive actions of drugs like prednisone.
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Staying Ahead of the Virus
In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Live or let die: the intracellular fate of pathogenic mycobacteria
How do mycobacteria subvert the defenses of host immune cells?
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Jorrit Rijpma en Amalia Campos Delgado nieuwe vertegenwoordigers regiogroep Latijns-Amerika en de Cariben
Met de benoeming van Rijpma en Campos Delgado is de Faculteit der Rechtsgeleerdheid in alle uniersitaire regiogroepen vertegenwoordigd.
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Inkomen en afkomst zijn risicofactoren bij kans op hart- en vaatziekten
Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…
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Crime and Migration in an Age of Transformation
The nineteenth century truly was an age of transformation. Throughout Europe processes of industrialization and urbanization, nationalization and centralization, changed the structures of society. It was an age in which the number of people living in urban communities grew substantially.
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Diagnosis of tuberculosis infection before immunosuppression
PhD defence
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Innate immune defence against intracellular pathogens
What are the host immune defence mechanisms that control intracellular infections and how are these subverted by pathogens?
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Efficient and flexible platform to isolate and study bacteriophages
We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.
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Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
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A much-needed new class of antibiotics
Antimicrobial resistance (AMR) is the phenomenon that pathogens become insensitive to the antibiotics that we use against them. A growing number of pathogens is becoming resistant, with methicillin-resistant S. aureus (MRSA) as the most famous example. But while the threat of AMR represents a slow-moving…
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof. dr. A.H. Meijer
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Een dag vol (nep)skeletten en mammoettanden
De Faculteit Archeologie bestaat dit jaar 25 jaar. Ter ere van dit jubileum opende de faculteit op 1 maart zijn deuren voor het brede publiek.
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Tradities van Gezag en Gezag van Tradities
Op 9 juni jl. vond in de rechtenfaculteitskamer van het Leidse Academiegebouw een workshop plaats over tradities en aanpalende concepten, zoals politieke cultuur, spelregels en constitutionele conventies. Tijdens de bijeenkomst presenteerden en bediscussieerden juristen, historici, politicologen en…
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Met senioren sjoelen en wandelen voor onderzoek
Student Marieke van der Heijden wandelt wekelijks met senioren bij het project Leren met de Stad. Zij doet onderzoek naar sociale cohesie in de wijk De Kooi.
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Soep en zwemmen: vrijwilligerswerk in je studententijd
Tijdens de facultaire introductieweek werden nieuwe bachelor studenten van de studies Rechtsgeleerdheid en Criminologie wegwijs gemaakt in het leren en leven aan de universiteit. Op de informatiemarkt van dinsdag stond niet het studeren centraal, maar het studentenleven. Studieverenigingen vertelden…
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The immune system: step it up or slow it down?
When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…
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Pauline Aarten and Marieke Liem in ‘Politie en Wetenschap’ with their new research
Commissioned by ‘Politie en Wetenschap’, Pauline Aarten, Assistant Professor at Leiden University, and Marieke Liem, Associate Professor at Leiden University, published their new research last week. The study
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Environmental and genetic drivers of wood and lignin formation in flowering plants
In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.
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Vijver en Barmentlo in radio show Vroege Vogels about Living Lab results
Water fleas and damselflies are much more sensitive to crop protection products in nature than in the lab. These test results from the Living Lab were presented by Henrik Barmentlo and Martina Vijver in Dutch radio show Vroege Vogels.
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Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
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Rethinking Javanese Religion: The Prospect of New Descriptions of Javanese Traditions
This study describes religion in Java.
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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Three questions about the new podcast Schandaal en Controverse in de Russische literatuur
Russian literature is awash with disputes, riots and intense political debates. In the new Dutch podcast Schandaal en Controverse in de Russische literatuur, senior lecturer Otto Boele and film maker and journalist Kay Mastenbroek discuss the most talked-about Russian books published in the past two…