Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…

Some people are predisposed to develop cancer. Mutations in genetic material that increase a person’s chances of developing cancer can already be present at birth. Researchers are closely examining these mutations to learn more about how cancer begins to develop.

Can epigenetic changes explain associations between early life stress and health outcomes?

In this thesis, classes of strongly interacting quantum field theories, have been studied.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

In September 2021, ACPA PhD Candidate Gabriel Paiuk will premiere a new work titled Sound Theory (The Clouds) as part of the 2021 Gaudeamus Muziekweek Festival. The performance will take place on September 10th, 20:30 at the De Helling (Utrecht, NL).

Can a new proteomics workflow be developed to link genes and gene clusters to bioactive molecules, identify novel compounds and enhance the production in the Streptomyces lividans enzyme?

Conspiracy theories are of all times, and the government should never dismiss them as a fantasy of fools. Certainly not now, when it turned out that authorities made a conspiracy themselves with a journalist threatened with murder. Which proves that the truth is always more insane than you could have…

As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.

Dividing Worlds: Tsunamis, Seawalls, and Ontological Politics in Northeast Japan

When professor Frank Israel graduated at Leiden Observatory some forty years ago, little did he know that one of his theories would be making headlines in 2018 - in the form of a 3D animation on the Internet, no less.

Leiden Professor of Number Theory Manjul Bhargava has been awarded a Fields Medal, widely regarded as the Nobel Prize for Maths. Bhargava is a professor in Princeton, and since 2010 has also been the holder of the Stieltjes chair in Leiden.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

On Tuesday 15 September 2015, Bart de Smit has been appointed as professor of Algebra and Number Theory at the Mathematical Institute of Leiden University.

‘I got into Nature last year, I was nominated for a faculty teaching award and my kids don’t care. But if your simulations get on The Big Bang Theory then that’s something!’ says Huib van Langevelde.

As of 1 June, Floske Spieksma has been appointed Professor at the Mathematical Institute in Leiden. Her field of study is Stochastic Decision-Making. Within this field, researchers develop mathematical techniques to analyse and improve processes within organisations. ‘As a professor, I hope to safeguard…

We aim to understand ion homeostasis in the model eukaryote S. cerevisiae.

CFP: Two-day PhD/ Research MA masterclass Feminist Theory with and around the work of Prof. dr. Lynne Huffer organised by the OZSW in cooperation with NOG

LCD screens use liquid crystals which have a high degree of order, even though they form a fluid. A new theory maps out the interplay between order, temperature and symmetry. Publication in Physical Review X.

Which brain cell does what, when Parkinson's disease arises? It won't be long before this jigsaw is solved piece by piece. Ahmed Mahfouz, computational biologist, combines bio-knowledge from Leiden with algorithms from Delft and is getting closer to finding the key.

In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.

Climate change is made up, the secret services murdered Pim Fortuyn and JFK, and the moon landing was a fake show. Conspiracy theories are of all times, providing sensation and entertainment, but also unrest and fear. The corona pandemic is new fuel for conspiracy theorists who set fire to 5G masts,…

The research is aimed at development of an efficient gene targeting method that allows controlled integration of DNA at a preselected site in the Trichoderma genome.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

What can Robotics and AI bring to archaeological theory and practice? In return, how can archaeology contribute to the developments in robotics and AI research? Colleagues tackled these questions at an event organised by the Faculty of Archaeology and sponsored by SAILS.

Following a special donation, the Stichting Pro Juventute foundation is facilitating a new special chair in Educational Theory and Law. Through the chair, Pro Juventute hopes to realise optimum child protection from a coherent legal and educational perspective.

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

Ten years after its introduction, the controversial idea of Erik Verlinde on gravity is still a hotly debated topic, and is still surrounded by a cloud of scepticism. Scepticism in which the media have played a major role, theoretical physicst Koenraad Schalm says in an article by NWO. ‘The media simply…

In this article, Jasmijn Boeken, explores in which ways the defining characteristics of the different zones can be found in the digital sphere.

How can zebrafish research help to understand and fight human cancer?

Pathogenic bacteria are increasingly resistant to today’s antibiotics. Professor Gilles van Wezel seeks new forms of antibiotics in good bacteria that live in the soil.

The ADAPTED (Alzheimer's Disease Apolipoprotein Pathology for Treatment Elucidation and Development) project is a major new initiative to investigate an area of Alzheimer's Disease (AD) research which has previously received little attention. The project aims to improve understanding of the function…

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

What is the origin of educational ideas, e.g., the idea that intervention in infancy has long-lasting effects on development.