2,637 search results for “discovery of the yuan” in the Public website
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Wil Roebroeks interviewed about new discoveries Borneo: "This killed Eurocentric views on early rock art"
In a remote cave on the Indonesian island of Borneo, a series of rock art paintings have been discovered. The oldest painting might be the oldest-known example of figurative cave art. Wil Roebroeks, not himself involved in this project, reflects on the findings in several media.
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Chemical Probe Facility
The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…
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The Dakhleh Oasis Project
Update : March 2020 A.J. Mills
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PhD Theses
A full overview of MacBio PhD Theses.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: M. Ubbink, Co-promotor: G. Siegal
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Studying Homo erectus Lifestyle and Location (SHeLL)
An integrated geo-archaeological research of the hominin site Trinil on Java
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MARBLES - Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases
To explore the potential of marine microorganisms as producers of novel antimicrobial agents and as bioprotectants in aqua- and agriculture, using an integrative, ecology-based strategy for bioprospecting.
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TOWARD A CINEMA OF UN-BELONGING: RITES OF PASSAGE FOR THE DIASPORIC ERA
Could an emergent Cinema of Un-Belonging discover forms of narrative time relevant to the long-term, inter-generational fractures caused by forced traumatic dispersion?
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Bioactive Molecules in Plant Sciences
Plant Sciences' contribution to the Bioactive Molecules research theme is to identify new plant bioactive molecules, and unravel their mechanisms of action in plant development or health, and the regulatory networks and (bio)synthetic pathways required for their production.
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Metabolomics Facility
The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…
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Sebastian Pomplun
Science
s.j.pomplun@lacdr.leidenuniv.nl | +31 71 527 4651
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Fundamental and translational medical biochemistry
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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Discovering and developing drugs
Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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Discovery Leiden nominated for KIJK: Best Tech-idea of 2021
Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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International Organisation
This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members examine the sources, design, effects and contestation of norms, rules, institutionalised practices and formal organisations that operate across national…
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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PhD: Targeting electron transport chain in Listeria monocytogenes for novel antibiotic development
Science, Leiden Institute of Chemistry (LIC)
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Role of leukocytes in metastasis formation in a zebrafish
How do macrophages and neutrophils contribute to metastatic onset?
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Tijm Lanjouw
Faculteit Archeologie
t.j.r.lanjouw@arch.leidenuniv.nl | +31 71 527 2727
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Maria Hadjigavriel
Faculteit Archeologie
m.hadjigavriel@arch.leidenuniv.nl | +31 71 527 6052
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Hilde Woker
Faculteit Rechtsgeleerdheid
h.j.woker@law.leidenuniv.nl | +31 71 527 2727
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Valentina Azzarà
Faculteit Archeologie
v.m.azzara@arch.leidenuniv.nl | +31 71 527 2727
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Roberto Arciero
Faculteit Archeologie
r.arciero@arch.leidenuniv.nl | +31 71 527 2727
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Freya Baetens
Faculteit Rechtsgeleerdheid
f.baetens@law.leidenuniv.nl | +31 71 527 2727
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Sam Botan
Faculteit Archeologie
s.a.botan@arch.leidenuniv.nl | +31 71 527 2727
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Maaike Warnaar
Faculty of Humanities
m.warnaar@hum.leidenuniv.nl | +31 71 527 7665
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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The Phantom of the Ego: Modernism and the Mimetic Unconscious
The Phantom of the Ego is the first comparative study that shows how the modernist account of the unconscious anticipates contemporary discoveries about the importance of mimesis in the formation of subjectivity.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors
Promotor: A.P. IJzerman
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Laura Heitman
Science
l.h.heitman@lacdr.leidenuniv.nl | +31 71 527 4558
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Who Framed King Tutankhamun?
The genesis of the golden boy-king mythos as exhibited between 1922 and 2022 in relation to Egyptological development with a focus on Dutch reception
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Typological tendencies in verse and their cognitive grounding
Knowledge and culture subproject 4:
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Research
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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Leiden Institute of Physics
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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Participants
The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).
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Converting cultural heritage into usable data
How can we make the information in handwritten historical research reports accessible and searchable? Data scientists at Leiden University are working with other universities on a method that will improve access to cultural heritage.
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Institute of Biology
Nature is a never-ending source of inspiration for the researchers at the Institute of Biology Leiden (IBL). Based on a better fundamental understanding of nature, they are able to seek solutions in the area of health and biodiversity. The theme of IBL is ‘Harnessing biodiversity for health.’
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Respiratory-chain enzymes
Many metalloenzymes that are key to bioenergetics are membrane enzymes, with canonical examples the complexes I, II, III and IV in the mitochondrial inner membrane. To study these enzymes in a native-like lipid membrane environment, we aim to develop novel bioelectrochemical techniques.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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FishForPharma: Training network on zebrafish infection models for pharmaceutical screens
How can zebrafish models be used to gain a better understanding of host-pathogen interaction mechanisms and to screen new drugs for infectious disease treatment?
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Yamila Miguel on Universiteit van Nederland
In a new video lecture (in English) on Universiteit van Nederland, astrophycisist Yamila Miguel tells us about the discovery of the most bizarre planets outside of our solar system.
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Jonathan Ouellet
Faculteit Archeologie
j.m.ouellet@arch.leidenuniv.nl | +31 71 527 2727
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Peter Akkermans
Faculteit Archeologie
p.m.m.g.akkermans@arch.leidenuniv.nl | +31 71 527 2391
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Anne van Dam
Faculty of Humanities
a.n.van.dam@hum.leidenuniv.nl | +31 71 527 2166
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Lauren Lauret
Faculty of Humanities
l.b.lauret@hum.leidenuniv.nl | +31 71 527 2772