In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

This volume edited by Jan Lucassen and Leo Lucassen aims to quantify and qualify cross-cultural global migrations and was published in the series 'Studies in Global Migration History'.

Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Studying the underlying principles of the nature of language.

Detection of cerebral beta-amyloid (Abeta) by targeted contrast agents remains of great interest to aid the in vivo diagnosis of Alzheimer's disease (AD). Bis-styrylbenzenes have been previously reported as potential Abeta imaging agents.

The Horizon 2020 project Sybil-AA (Systems Biology of Alcohol Addiction) focuses on modeling and validating disease state networks in human and animal brains for understanding pathophysiology, predicting outcomes and improving therapy in alcohol addiction. Alcohol addiction, the most severe form of…

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

Plant-microbe interaction resulted in different physio/chemical responses by host plant and interacting rhizobacteria.

The Faculty of Humanities

Cognitive psychology is the study of cognitive functions such as attention, memory, consciousness, emotion, language and action control. The goal is to understand the complex relationships between brain, mind and behavior.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

High resolution altitude data created by airborne LiDAR allow the investigation of large areas and often inaccessible tracts of land and has the potential to reveal undiscovered archaeological heritage.

The mechanism of the electrochemical reduction of dioxygen by a mononuclear pyridylalkylamine copper complex was investigated (see picture). It was shown that in neutral aqueous solution dioxygen undergoes stepwise reduction, wherein hydrogen peroxide plays a key role. The rate constants determined…

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Promotor: V. Vitelli, Co-promotor: J. Paulose

Our cantilevers have a low intrinsic damping rate: this enables us to measure with low noise, since damping is proportionate to noise. However, when the magnet is close to the surface of a sample we want to study, we measure a much higher effective damping rate. This is caused by magnetic interaction…

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

This thesis focuses on protoplanetary disks: flattened structures of gas and dust around young stars in which planets are expected to form and grow.

In the contemporary myriad of definitions and approaches of landscape, the starting points and limits of the concept of landscape biography are being explored, but also tested in this thesis. What exactly is a landscape biography? What does it constitute of? Is landscape biography just a narration of…

Promotor: Prof.dr. T. Hankemeier, Co-Promotor: R.J. Vreeken

This research note argues that the “lone wolf” typology should be fundamentally reconsidered.

Promotor: Prof.dr. C.W.J. Beenakker

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

The programme group Research Methods and Statistics offers methodological support in many projects in the field of education and child studies.

And its application in deciphering hominin diets in palaeolithic eurasia

The University’s Vision on Student Well-Being outlines how the University plans to promote student well-being in the coming years.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Cyber security is one of the critical challenges in our inter-connected world. Organizations are being constantly targeted by adversaries. Various critical systems become exposed on the Internet. Users can find that their data has been stolen from a company that they were not even aware of.

The overall objective of this project is to identify novel drug candidates that are capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multimodal phenotypic characterisation of cohorts of monogenic PD…

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

Promotor: Prof.dr. D. Bouwmeester, Co-promotor: M.P. van Exter

To study how planetary systems come into existence we study much younger systems still in formation.

Can animal venoms yield novel antimicrobial peptides?

Our current research focusses on the exploration of the Universe using the neutrino. This neutral, almost massless and only weakly interacting particle can open a window to the distant Universe and also dense regions from which photons cannot escape.

The main focus of this thesis is the behaviour of two-dimensional materials, namely (anti)-ferromagnetic materials in the first two chapters, which show topological phases, and energetic square ice in the third and fourth chapter.

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

Three major cosmology-focused missions are planned for the next decade: the Euclid space telescope, the Vera C. Rubin Observatory in Chile, and the Nancy Grace Roman Space Telescope.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

More than 5,000 exoplanets have been found over the past couple of decades. These exoplanets show a tremendous diversity, ranging from scorching hot Jupiters, common super-Earths, to widely separated super-Jupiters on the planet/brown dwarf boundary.

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

Lecture, Studium Generale

In a new study, we found that when we are exposed to potential harm to the other person, it improves our automatic attentional processes to avoid harm to that person.

Filipino anthropologists Andrea Malaya M. Ragragio and Myfel D. Paluga look back at the groundbreaking Netflix show Trese and what it missed about the stories of Indigenous peoples. They published the article 'What Netflix Got Wrong About Indigenous Storytelling' in the digital Anthropology magazine…

LCN2 organizes seminars on the last Friday of each month.