LED3 is the combined effort of three excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the three institutes.

At the New Year’s reception of the Faculty of Science on 6 January, it was announced that Annelien Zweemer, Leiden Academic Centre for Drug Research, has been awarded the ‘Discoverer of the Year 2014’ prize. Matteo Brogi, Leiden Observatory, wrote the best dissertation in 2014 and Dennis Claessen, Institute…

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

The IBL represents the core of modern biological research at Leiden and we interact closely with the other life science Partner Institutes in the faculty:

Overkleeft

Development & demonstration of low environmental impact innovation and optimization practices in pharma production.

Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars (exoplanets). They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems. This way they address…

Assistant Professor at the Department of Analytical Chemistry, Radboud University Nijmegen, the Netherlands

Contact Metals in Catalysis, Biomimetics & Inorganic Chemisrty

This Thesis shows discoveries in non-linear astrochemical kinetics as well as a deeper analysis of dark clouds chemistry.

The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…

Science, Leiden Institute of Chemistry (LIC), Leiden Institute of Physics (LION)

As a venue, Leiden University is a fitting setting for recognising the outstanding achievements of the award winners and celebrating the inspiration that they bring as role models for encouraging a fairer society by motivating one individual at a time.

The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…

An overview of awards and prizes granted to our staff and students in 2017, as well as special appointments and royal distinctions.

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Twenty years from now, the world population is estimated to be around 9 billion people (now 8 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this population will result in an enormous increase in the demand for food, consumables, water…

Research at the SBC group is comprised of the following research themes:

Some examples of AI-research done at Leiden.

Which teacher did an outstanding job in not only transferring knowledge in novel ways but also in getting students enthusiastic and connecting a course to current research themes? Meet the nominees for the Teacher of the Year Award 2024!

Your time in Leiden is about more than just studying. Some of your best experiences will come from being part of our vibrant and diverse student community, and from living in the beautiful city of Leiden.

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The LED3 hub, consisting of researchers from the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden (IBL) and the Leiden Academic Centre for Drug Research (LACDR), is very excited to organize the “LED3 Lectures”. This lecture series brings world-leading researchers in the field of…

Dishoeck

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

When you apply for admission, you’ll be asked to submit several documents.

The Graduate School of Science offers PhD programmes spanning the entire spectrum of science from Mathematics to Environmental Science.

The Department of Biophysical Structural Chemistry studies how biological systems work at the molecular level through high-resolution structural analysis. Using state-of-the-art techniques in structural biology such as cryo-electron microscopy and X-ray crystallography we gain crucial insights into…

Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).

Can new variants of daptomycin and the polymyxins be found?

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: S. Ioppolo, H.M. Cuppen

Dr. at the Department of organic chemistry, Wageningen University - the Nederlands

Leiden University has developed a radically different method for large scale production of diverse nanoparticles and their alloys.

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…

This thesis systematically analyzes the physical-chemistry of lipid-graphene interactions with the major objective of reconciliating the variety of results reported in the literature.

Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…

In 2024, many of our students and staff won great prizes and secured important research grants.

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

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Siemens recently took over the Leiden software company Culgi, founded by professor and inventor J.G.E.M. (Hans) Fraaije. We spoke to him about the algorithm that made him successful, the role of a university in our society and his ambitions at Siemens. ‘I was looking for Siemens, and they were looking…

There are eight institutes at the Faculty of Mathematics and Natural Sciences:

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