The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Research at the Macromolecular Biochemistry group is comprised of the following research themes:

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

How does the photoregulation mechanism work in detail?

How did dynastic organization – that it, the employment of non-ruling family members and the development of dynastic traditions and concepts – influence state formation in both Catholic Europe and Muslim West-Asia?

Following its foundation in 1575, Leiden University was quick to incorporate Roman goddess Minerva in its coat of arms. This explains why Rembrandt’s Minerva from 1635 can be seen on the façade of the Academy Building, which has been in use by the University since 1581. This is where, in the Senate…

In the hunt for a vaccine against cervical cancer, fundamental knowledge about the immune system and organic chemistry have been brought together and have already resulted in a vaccine that is now being tested in clinical trials. Scientists are now working hard on an improved variant.

This dissertation examines whether a cochlear implant provides congenitally deaf born children with sufficient auditory input to acquire low salient and syntactically and semantically complex functional items such as personal pronouns compared to their hearing peers.

Key publications of the Medical Systems Biophysics and Bioengineeringgroup (Mashaghi Lab)

Monica Kaminska, Dennis Broeders and Fabio Cristiano have contributed a chapter to the proceedings of the 13th International Conference on Cyber Conflict (CyCon 2021), which gathers 20 articles from the law, technology and strategy domains.

Can a proposed new radiofrequency approach to graphene biosensors lead to groundbreaking changes in genome mapping?

Research question

An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.

Source: Mol Psychiatry (2015)

How are carbohydrates processed by the immune system? Can carbohydrates be used to trigger T-cells against other conjugated antigens? Can they be used as adjuvants?

Participation in the matching module is a compulsory part of the admission and application procedure for all applying students of this programme.

BSc Cultural Anthropology and Development Sociology is a bachelor’s programme with a compulsory matching module.

Despite an increased EU role in the preparedness, monitoring and coordination of health emergencies over the past two decades, Member States’ responses to the first wave of COVID-19 were surprisingly uncoordinated. In light of calls to improve cooperation regarding future health emergencies, this article…

The Faculty of Medicine

LUCAS members are experts in the fields of literary history and theory, film and media studies, and art, architectural, and book history.

Participation in the matching module is a compulsory part of the admission and application procedure for all applying students of this programme.

The CIGR comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…

The Leiden University’s Program for Cyber Norms, a research platform to investigate the development and implementation of law and policy applicable to uses of ICTs, in cooperation with the think-tank ICT4Peace conducted a global open consultation on how to implement the UN Group of Governmental Experts’…

Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…

Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.

Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.

Debate, Roundtable discussion

The student navigator 'Find your way' helps students find their way around the university. Student advisers can also be found on the roadmap. JanPieter, student advisor at the Institute of Security and Global Affairs (ISGA), explains what a student advisor does.

What do you do if you have a book from the sixteenth or seventeenth century, but you suspect that the binding contains a fragment of a medieval manuscript? University lecturer Thijs Porck has received an NWO grant to experiment with a camera attached to a tube. 'The project boils down to keyhole surgeries…

Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…

Relevant publications of the CIGR participants.

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic ‘spike protein.’ They predict which antibodies would provide the best protection against the…

Advanced fluorescence microscopy techniques have revealed how steroid receptors move inside the nucleus. The results were published by a team from Leiden University and the Erasmus Medical Center in Rotterdam, led by IBL-researcher Marcel Schaaf.

Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.

This project aims to design Principles and Guidelines to improve coordination between courts in Europe for insolvency and related proceedings.

Digital technology is changing academia and society at lightning speed. LIACS is in the midst of this with groundbreaking research into data processing and artificial intelligence (AI). It conducts a unique combination of fundamental and applied research into major issues facing academia and society…

Kros

Key publications of the Predictive Pharmacology group.

The physical features of twelfth-century manuscripts from the Flemish abbey of Ter Duinen – such as script, page layout, and reading aids – show how their readers organized, interpreted, and transmitted knowledge.

This book presents concrete solutions for managing the legal risks distorting the development of various areas of EU law. It pursues an innovative and effective approach to identify legal risks, their causes at the EU level and their impacts on the functioning of the Union and its Member States. It…

Research at the SBC group is comprised of the following research themes:

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

Requirements for admission to the Graduate School and the steps described below in short are described in detail in the Leiden University PhD Regulations.

What is a good data protection law? How does a good data protection law evolve? Is European data protection law a good one? And whether the European data protection applicable to China?

How do inclusion and exclusion affect people?

Religion, Philosophy, and the Pre-modern World