980 search results for “bacterial stress” in the Public website
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Occupational health in the Emergency Department: A study on work-related factors and health/well-being in nurses and doctors in 19 Emergency
Occupational health in the Emergency Department
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Innovative diagnostics and treatments
The more we learn about a (neuro-)psychological or physical disorder and the related behavioral factors, the better we can not only identify them, but also treat them. It is therefore important that recent insights about (neuro-)psychological problems and related behavioral factors are incorporated…
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Empathic or anxious mistakes?
Empathic or anxious mistakes? A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments
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Effects of noninvasive vagus nerve stimulation on perseverative cognition
Can excessive worrying be reduced via stimulation of the vagus nerve?
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Research
The aim of our research program is to better understand the aetiology and course of mood, anxiety and trauma and stressor-related disorders and to test and improve treatments for these disorders.
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Cognitive and behavioural emotion regulation after negative and traumatic life events
To study relationships between emotion regulation after negative and traumatic life events and psychopathology. Within this context, another goal is to develop and validate emotion regulation questionnaires.
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REACT Study
The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…
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A sustainable environment
Making public space more sustainable is considered very important in this project. The Humanities Campus will become a pleasant place to spend time, with lots of greenery. Here, people can relax and find coolness on hot summer days.
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Development & Disease
Development & Disease is one of the four research themes of the Institute of Biology Leiden.
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People and Projects
Our team consists of the following members.
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NWO grants two IBL-proposals by interdisciplinary research consortia
Recently, NWO has decided to grant two interdisciplinary research proposals for national and international consortia submitted by researchers from the Institute of Biology Leiden. One of the proposals is led by Prof. dr. Ariane Briegel, the other one by dr. Remko Offringa.
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Physiological responses to a social-evaluative situation
How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…
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RESIST Study
Knowledge of mental distress and resilience factors over the time span from before to after a stressor is important to be able to leverage the most promising resilience factors and promote mental health at the right time. To shed light on this topic, we designed the RESIST Study, in which we assessed…
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Topic: E-health
The research connected to this topic is related to E-health.
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A PCAD-model for fish to study the impact of airgun sound exposure on free-ranging cod
We are developing the conceptual framework, which is new to this taxonomic group, and evaluate the current state of the art with respect to all critical parameters and transfer functions for a fully developed Population Consequences of Acoustic Disturbance (PCAD) model.
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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Sociaal gedrag als onderdeel van coping styles in zebravis
Zijn sociale aspecten van anxiety-like gedrag bij zeer jonge zebravissen al aanwezig? Zijn deze afhankelijk van de coping style (persoonlijkheid) van het individu? Zijn deze gedragingen endocrien te moduleren, bv door oxytocine?
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Studies on the Pathogenesis of Chronic Kidney Disease
In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…
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Arabic and Aramaic in Iraq: Language and Syriac Christian Commitment to the Arab Nationalist Project (1920-1950)
Tijmen Baarda defended his PhD thesis on 8 January 2020
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Evaluation and implementation of innovative diagnostics and treatment
If a new method has been developed to recognize and treat a (neuro-)psychological disorder or related behavioral factors, it cannot yet be used directly in clinical practice. First, the method should be evaluated, preferably in randomized controlled trials.
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Evolution & Biodiversity in Animal Sciences
Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.
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EEG theta\beta ratio as a potential biomarker for resilience to performance anxiety.
Is EEG theta\beta ratio predictive towards the negative effects of stress on cognitive performance in individuals suffering from performance anxiety? Can we improve resilience to performance anxiety by using a theta\beta ratio neurofeedback intervention?
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Research
How do people acquire language? How can you train your brain? What is the effect of stress on an unborn child? LIBC research topics range from language processing to cognitive robotics, and from psychiatric disorders to the impact of social factors on human behaviour. Meet several main research topics…
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Mental wellbeing
You can find some tips here on how to maintain your mental health.
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Anne Krause-Utz
Faculteit der Sociale Wetenschappen
a.d.krause@fsw.leidenuniv.nl | +31 71 527 6639
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Salma Balazadeh
Science
s.balazadeh@biology.leidenuniv.nl | +31 71 527 4790
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Key publications
Key research articles and book chapters of the Chromatin group.
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LHSC booster grants
The LHSC booster grants awarded are described below. The summaries below are aimed at the general public. For further detail, please contact the researchers in question.
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Bacteria inside plant roots battle fungal disease
Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…
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Delivery of Biotherapeutics
The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Self-assembly properties and applications of metal-binding peptides and proteins
It is estimated that approximately 30% of all proteins require a metal to function. Investigating the relationship between metal-binding and peptide/protein folding allows us to uncover fundamental rules for creating metallo-peptides and proteins, which in turn leads to the creation of new structures,…
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Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
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History of Leiden University
Read on these pages all about the history of Leiden University, the oldest university in the Netherlands. The Academia Lugduna Batava was founded in 1575 and its motto is: Libertatis Praesidium ('Bastion of Freedom').
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Nitric oxide in defence against mycobacterial infection
Can we enhance the capacity of host immune cells to kill mycobacteria via production of reactive nitrogen species?
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Proteochemometric modelling coupled to in silico target prediction
An integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small molecules.
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Animal Sciences
We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.
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Horizontal gene transfer and spreading of biosynthetic gene clusters and antimicrobial resistance
Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.
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Novel approaches to develop filamentous micro-organisms for enzyme production (FILAZYME)
Can we develop new enzymes and cell factories to upgrade current enzyme cocktails towards complete degradation of biomass?
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Cancer Therapeutics and Drug Safety
In this research group, headed by Bob Van de Water, cell signaling programs that underlie adverse drug reactions as well as cancer development and progression are unraveled. Adverse drug reactions involve cell injury in critical target organ cells which leads to the activation of cellular stress response…
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Environmental and genetic drivers of wood and lignin formation in flowering plants
In this project, we will study the genetic and environmental drivers of woodiness and stem lignification at the level of plant‐to‐gene‐to‐molecule.
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Topic: Novelty and enrichment
One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…
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Participants
The CMCB comprises research groups from the Institute of Biology Leiden (IBL), the Leiden Institute of Chemistry (LIC) and the Leiden University Medical Center (LUMC).
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What does word stress tell us about morphological structure?
Lecture
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RAISE Study
The aim of the RAISE study is to investigate how resilient people respond to stress. Specifically, we will study how key biological systems (HPA-axis, immune system) interact with the brain and social environment in order to facilitate resilient functioning after childhood adversities.
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Exploring novel regulators and enzymes in salicylic acid-mediated plant defense
Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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Signalling pathways that control development and antibiotic production in streptomyces
Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.
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Genetic, biochemical and neural correlates of vulnerability to depression.
How do genetic and environmental factors make us vulnerable to depression?