234 search results for “bacterial” in the Public website
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Disrupted movement makes macrophages more lethal to tuberculosis bacteria
Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…
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Drugs with fewer side effects through a collaboration between LACDR and PTS
LACDR, the Leiden Institute for Drug Research, developed better tolerated excipients to prevent adverse effects related to the surface of nanosized drugs such as vaccines. LADCR professor of Biopharmacy Matthias Barz and Polypeptide Therapeutic Solutions (PTS) are collaborating to develop processes…
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Altruism in bacteria: colonies divide the work
Bacteria found in soil specialise in the colony by division of labour. Some of the bacteria produce antibiotics, even when it comes at the expense of their individual reproduction success, to defend their colony against competitors. Publication in Science Advances.
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Three awarded research projects in NWO-XS call
Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.
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Bacteria without cell wall gobble up DNA from environment
A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…
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Hypoxic Signalling and Tuberculosis
IBL-researcher Phil Elks in the group of Annemarie Meijer won the Cell Observatory Publication of the Year 2013. He received the award for his paper in PLoS Pathogens, showing that activation of hypoxia signaling protects against mycobacterial infection.
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Science and business working together on affordable alternatives for antibiotics
Almost fifty scientists and twenty companies will be working on developing new antibiotics and alternatives for antibiotics use. NWO and the Ministry of Health, Wellbeing and Sport will together invest close to seven million euros in this research. Scientists from Leiden University and LUMC will be…
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Bacteria that degrade plastic: Unilever Research Prize for master’s student Jo-Anne Verschoor
Jo-Anne Verschoor wins the Unilever Research Prize 2020. The master's student in Biology developed a method to test whether bacteria are capable of degrading plastic. Verschoor: 'Using specific enzymes from these bacteria, we may be able to efficiently recycle plastic in the future.
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'One in five bacteria we tested were capable of breaking down plastic'
Leiden PhD candidate Jo-Anne Verschoor discovered that nearly twenty percent of the bacterial strains she studied could degrade plastic, though they needed some encouragement to do so. ‘Bacteria are just like people,’ says Verschoor. Her research was published in the journal Communications Biology,…
- IBL Symposium 2022
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Seven Leiden professors elected new members of KNAW
Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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Scientists find strong evidence that wasting syndrome is the same for all organisms
An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…
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Artificial intelligence helps in the search for new antibiotics
With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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Dangerous microbes in lower level safety lab? A new technique could make it possible
Researchers need to work in specialized environments when they work with dangerous bacteria and viruses. These microbes spread easily, so only in labs with a high biosafety levels they can be studied. Unfortunately, to look at the microbes properly, expensive microscopes are needed that are not always…
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Veni grants for eleven Leiden researchers
Eleven Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant will enable them to develop their research ideas for a period of three years.
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Aphid genome unravelled
Leiden evolutionary biologist Maurijn van der Zee has co-operated on an enormous international project to describe the genetic material of the pea aphid Acyrthosiphon pisum. The more than 100 authors involved in the project have published their findings in the online magazine PLoS Biology.
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Bacteria stunt with established plant-soil feedback theory
‘What I find most alluring about soil life is that you can steer it,’ researcher Martijn Bezemer of the Institute Biology Leiden (IBL) reveals. ‘You can ask: What do you want? And then I can transform the soil into something you need. At least, that is what we thought.’
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Three LUF grants for talented Leiden Science researchers
Fighting against cancer, antibiotic resistance and disposable plastics: Ahmed Ali, Fredj Ben Bdira, and Valerio Barbarossa receive a LUF grant for their innovative and socially relevant research. These grants for academic talent are often an important step towards grants by NWO and other grant insti…
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Six million boost to search for new antibiotics
Edith Schippers, Minister of Health, will be investing six million euros over the coming four years to boost research on new antibiotics. The programme will be set up by several different parties, including the Leiden Centre for Antimicrobial Research.
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Spinoza Prize for astrophysicist Ignas Snellen
With his clever measuring methods Ignas Snellen – together with his team – was the first to detect carbon monoxide in the atmosphere of exoplanets. For his pioneering work the Leiden astrophysicist has been awarded the Spinoza Prize, the highest academic honour in the Netherlands. The prize of 2.5 million…
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Students hunting for breakthrough in antibiotics resistance
Bacteria that fluoresce green, blue or red may play a role in combatting resistance against antibiotics. Under the motto of 'Say yes to stress', thirteen ambitious Leiden students are aiming to amass 9,000 euros to carry out their research project.
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Tracers that light up tumours help surgeons
How do surgeons avoid causing nerve damage or leaving cancerous cells behind? An interdisciplinary research group at the LUMC hopes to improve operations and make them less invasive with the aid imaging techniques. They are working with medical companies to make these techniques widely available.
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Improving Nature’s Antibiotics to Overcome Resistant Bacteria
Lecture, NGL-lezing
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Mighty microscopy
Festival
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Using cryo-EM methods to uncover structure and function of bacteriophages
PhD defence
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Publications
Recent publications
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What a glow in the dark squid tells us about the human gut microbiome
Lecture, Tuesday Talks: Science Insights
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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Joan van der Waals colloquium
The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.
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Older publications
Overview of the publications of the department of Environmental Biology (1972-2015)