2,483 search results for “center drug discovery initiative” in the Public website
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‘The sun is dying out’ as a wake-up call for better science communication
‘Take science communication more seriously.’ This is the message that Ivo van Vulpen, professor by special appointment in Science Communication in Physics, wants to convey during his inaugural lecture. At the moment, a lot of researchers look down their noses at this while it is extremely important…
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Linguistic time travel
A love of puzzles and the patience of a saint: these are two essential traits for linguists wishing to explore the Indo-European language family. Fortunately, Professor Michaël Peyrot possesses both. In his inaugural lecture he will take the audience on a voyage of discovery to the past.
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Adapt or perish – traits identified that help plants survive
PhD candidate Jianhong Zhou aimed to better understand whether and how plant species adapt to environmental changes. She developed two databases that she used to analyze how easily or difficultly plants adapt to changing conditions. Zhou defended her PhD thesis on 4 September.
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Opening Gorlaeus Building celebrated grandly
Confetti, stilt walkers and the new Einstein Fountain. On Monday, 2 September, the Gorlaeus Building of the Faculty of Science was festively opened. Together with Constantijn van Oranje, our students cut the ribbon. Dean Jasper Knoester: ‘The building is ready, now it is up to our students and researchers…
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Dozens of massive stars launched from young star cluster R136
Astronomers have used data from the European Gaia Space Telescope to discover 55 high-speed stars launched from the young star cluster R136 in the Large Magellanic Cloud, a satellite galaxy of the Milky Way. This increases tenfold the number of known “runaway stars” in this region. The team of astronomers,…
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Nadine Akkerman: ‘It’s an incredible feeling, rewriting such an iconic event from a country’s history.’
Ever since Nadine Akkerman, Professor of Early Modern Literature & Culture, came across a woman spy in her research, secret agents have kept cropping up in her work. Now there’s Spycraft, a popular history book exploring the espionage techniques used by early modern spies, which she has co-written with…
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Astronomers Discover Ancient Solitary Quasars with Mysterious Origins
An international team of astronomers, including Leiden PhD student Elia Pizzati, has observed several ancient quasars that, surprisingly, appear to be floating alone in the early universe (less than a billion years after the Big Bang). Until now, astronomers, based on models, assumed that quasars are…
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Research offers surprising insights into historical crime in The Hague
Theft, prostitution, fortune-telling or murder. Historian Manon van der Heijden and a group of students are researching court records from The Hague from 1600 to 1800. They are tracing crimes and offenders and shedding new light on The Hague’s Gevangenpoort (or Prison Gate). Among their many discoveries…
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Sleep and circadian rhythms: The effects of ketamine, caffeine and anthracyclines
PhD defence
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Triblock Polypept(o)ides for siRNA Delivery
PhD defence
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Semisynthetic Glycopeptide Antibiotics
PhD defence
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Antiviral strategies against emerging coronaviruses
PhD defence
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Leiden scientists develop topological barcodes for folded molecules
The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…
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Thorbald van Hall delivers inaugural lecture on training the immune system to counterattack escaping tumours
On 10 September 2021, Professor Thorbald van Hall from the Department of Medical Oncology in the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Tumour-immune interactions: control, escape and counterattack’. Van Hall used the opportunity to describe how - in a similar way to…
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.
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How microscopic scallops wander
All microscopic objects, from enzymes to paint particles, are jittering constantly, bombarded by solvent particles: this is called Brownian motion. How does this motion change when the object is flexible instead of rigid? Ruben Verweij, Pepijn Moerman and colleagues published the first measurements…
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Vidis for eleven Leiden researchers
Eleven talented Leiden researchers with several years of research experience have been awarded a Vidi subsidy to set up or expand their own line of research.
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Understanding metastasis: Science Groot grant for Erik Danen
A team led by Erik Danen from the Leiden Academic Centre for Drug Research has received a 3 million euros NWO Science Groot grant to unravel the first steps of metastasis. Danen will work together with biologists and theoretical and experimental physicists from Dutch Universities. ‘Understanding these…
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A game of Mastermind to unravel Alzheimer’s disease
In order to better understand the course of Alzheimer’s disease, Frédérique Kok believes that a strategic and structured approach is needed: the Mastermind research approach. With her LUF grant, Kok wants to generate high-quality data to build a mathematical model that can recognize the onset of the…
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One step closer to pain-free vaccinations
Microneedles are a promising tool for the painless administration of vaccines through the skin. But, are these minuscule needles really effective? PhD student Pim Schipper of the Leiden Academic Centre for Drug Research investigated various factors of vaccination via the skin and discovered, among other…
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Vivian Ng: ‘Because of my job, I’m meeting new people, so it doesn’t feel like working to me’
Vivian studies the Global Political Economy specialisation of the MA International Relations and is the coordinator of the Humanities Buddy Programme. Originally from Malaysia, she has been studying abroad in various places. At Leiden, she focuses her studies on illicit political economy and ensures…
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Better treatment of systemic autoimmune diseases requires close collaboration
Exceptional collaboration between physicians is needed to better understand and treat autoimmune diseases that cause inflammation in various organ systems.
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'Impact of information technology on Marechaussee’s border controls is limited'
The Schengen Agreement has resulted in systematic border controls between EU Member States largely ceasing to apply. Solutions for the associated security risks are often sought in information technology. Tim Dekkers investigated how such technology is applied in this context and will defend his PhD…
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Dealing with the Dutch
Learning to cycle without a handbrake, saying sorry if you're late for a lecture and fathoming out the weird sounds of Dutch. Leiden's new international students get a crash course in Dutch culture during their introduction week.
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Minor Violence Studies: interesting encounters and flying wooden blocks
The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Leiden University shows its face on 3 October
Leiden University celebrated the Relief of Leiden with the 3 October University. This year the University also took part in the festive parade, to promote 444.
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Leaving Afghanistan: ‘Tensions with Russia and China are rising further’
After an extremely painful conclusion, the Western allies have left Afghanistan and the Taliban have regained supremacy. How will Afghanistan move forward, and what does the departure mean for global relations? Rob de Wijk, emeritus Professor of International Relations and Security, analyses the failure…
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Juvenile or criminal law for young delinquents? Alumna Maaike Kempes is on the case
As an enthusiastic nature lover, Maaike Kempes began studying biology at Leiden University. Now, she is extraordinary professor of Forensic Neuropedagogy at the faculty of Social Sciences. She is researching how neurobiology plays a role in delinquent behaviour among young people. ‘They’re like Ferraris…
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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Stressed brain, stressed heart?
Ilze Bot and Johan Kuiper have published in The Lancet: Study unveils how stress may increase risk of heart disease and stroke. Aso: The National Dutch newspaper 'NRC' has mentioned them in a column
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ILS 2.0: The three winning proposals 2016-2020
The research profile area Interaction between Legal Systems has a multidisciplinary approach and aims to inspire innovative research. Out of all the proposals put forward, three winning projects have been selected for the forthcoming research period 2016-2020.
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Faculty of Science starts new year with awards for talents
Mathematician Robbin Bastiaansen, physicist Irene Battisti, pharmacist Fouzia Lghoul-Oulad Saïd and physics and astronomy student Maite Boden are the winners of the annual prizes of the Faculty of Science. Boden was honoured as the first Young Star, a new prize for the best bachelor’s student of the…
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New statistical method brings together studies at an early stage
During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…
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How to make cryptographic techniques more efficient?
Sharing scientific data, transferring money, or sending other sensitive information online: with cryptography, applications make sure your data does not fall into the wrong hands. Mathematician Thomas Attema (CWI/TNO/Leiden University) helps with this. For his PhD research, he developed a new technique…
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Using tweezers of light to study the misfolding proteins of muscular diseases
Alireza Mashaghi from the Leiden Academic Centre for Drug Research (LACDR) will use state-of-the-art technology to investigate proteins that play a role in muscular dystrophy. His goal is to provide new insights for designing novel therapeutic strategies in the future. To accomplish this, Mashaghi receives…
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Finding the cause of memory loss
Memory loss and confusion are signs of Alzheimer’s disease. Physicists Serge Rombouts and Martina Huber have developed new methods to help medical science get to the bottom of this insidious disease.
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How NeCEN helped develop the Johnson & Johnson Covid-19 vaccine
The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.
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‘The question is more important than the answer’
Francesco Ragazzi loves to talk about international relations. But what makes him really happy is if his students question the discipline. This has won him a nomination for the LUS Teaching Prize. Is he the best lecturer for 2019?
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Double inaugural speech: how social context influences processes in the brain
It’s not a regular occurrence at Leiden University: two professors giving their inaugural lecture on the same day. Berna Güroğlu and Ellen de Bruijn specialise in related disciplines: they both research the influence of social context on processes in the brain – Güroğlu in adolescents and De Bruijn…
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'Satisfied students give me more fulfillment than getting a research grant'
Imparting students with a critical attitude and cross-curricular skills. That is what Rawi Ramautar wants to strive for as the new programme director (OD) of the bachelor of Bio-Pharmaceutical Sciences. 'A programme director has to create a programme of which students say: I find it challenging and…
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Pitfalls of discretionary conduct
Judicial officers have some leeway in how they act. In most cases that's fine, but it can also lead to abuses, such as ethnic profiling. It is easy to forget that these are not isolated decisions, but are also part of a framework of formal policies. Professor Maartje van der Woude calls for more comprehensive…
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Dick Stufkens Prijs 2010 awarded to chemist Niels Elders
The Dick Stufkens Prijs 2010 is awarded to Dr. Niels Elders. The prize is given by the Holland Research School of Molecular Chemistry for his Ph.D. thesis “Multicomponent Approaches to Molecular Diversity & Complexity”, in which he describes the development of various new multi-component synthetic procedures…
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Ten years ERC: Sylvestre Bonnet kills cancer with light
In 2013, Sylvestre Bonnet received an ERC Starting Grant to kill cancer with molecules that can be activated by light. Two postdocs and three PhD students later, the end approaches of his so far successful project.
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NWO grant for research facility into the impact of environmental factors on health
What is the influence of non-hereditary factors on our health, such as lifestyle, diet and exposure to harmful substances? The Exposome-Scan project, led by Leiden professor Thomas Hankemeier, has been awarded 3.2 million euros from the NWO Investment Grant Large programme to answer this question. With…
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Student mental health problems still common but less so than in covid year 2021
The number of students suffering from stress and anxiety has decreased slightly compared with 2021. But around half still suffer from mental health problems. This is according to the National Mental Health and Substance Use Monitor.
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It’s all about the cell wall for brand-new professor Dennis Claessen
Dennis Claessen has been appointed professor of Molecular Microbiology at the Institute of Biology Leiden. With his teaching and research on the cell wall, the professor wants to establish applications in the industry and the medical sector.