Current antibiotics only address very few target proteins in bacteria to kill them. Researchers know that there are more possible target proteins to tackle the bacteria. The question is: which ones. Thanks to the NWO Vidi Grant, Assistant Professor Molecular Physiology Stephan Hacker and his team can…

Fiction is more effective than autobiographical non-fiction when it comes to conveying the sensation of enforced solitary confinement. That is the conclusion of writer and lawyer Maarten Asscher in his study 'Het uur der waarheid. Over de gevangenschap als literaire ervaring' (The Moment of Truth: Imprisonment…

Research conducted at Leiden has established that guts-on-chips respond in the same way to aspirin as real human organs do. This is a sign that these model organs are good predictors of the effect of medical drugs on the human body. Publication in Nature Communications on 15 August.

Leiden chemists have created a new ultrathin membrane only one molecule thick. The membrane can produce a hundred times more power from seawater than the best membranes used today. The researchers have published their findings in Nature Nanotechnology.

Niall Hodgins, master student Biology and Science Based Business, has earned the right to call himself the best student entrepreneur in Leiden. On June 15th 2016 he won the finals of Gulliver and the associated 10,000-euro prize for his company NADES to continue developing solvents for use in preclinical…

IBL-researchers revealed in a new study that insects are successful on land because their eggs became protected against desiccation. An extraembryonic membrane in the egg, the serosa, helped insects to make the transition from water to land.

Do medicines arrive in the right amount at the right spot in our brain? By making a model that depicts our brain in small 'brain blocks', Esmée Vendel tries to find an answer to this question. Her new, mathematical model predicts the concentration of medicines in the brain over time and space. Vendel…

Antibiotic-resistant bacteria are a major problem worldwide. Molecular biologist Changsheng Wu explored innovative methods of developing new antibiotics more simply and more easily. He also discovered a new type of antibiotic.

The new project INFLANET will train young scientists in Europe to become experts in inflammation research. Professor Annemarie Meijer from the Institute of Biology Leiden coordinates the training.

Visualising cell proteins without invasive techniques is possible with the help of fluorescence. During a lecture of the Natuurwetenschappelijk Gezelschap Leiden on 18 January, winner of the Spinoza Prize 2017 and founder of the field of single molecule optics Michel Orrit explained how this works.

In the Gorlaeus Building, there will be a brand new faculty bar for students and staff. From hundreds of entries, a faculty jury chose the name for this bar. The new bar will be called 'The Fusie'. 'This name exudes togetherness and cosiness,' says FWN assessor Nalani Verwoord. 'And it has an additional…

Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’

Ariane Briegel, Professor of Ultrastructural biology in Leiden, has received a prestigious incentive from the Gordon and Betty Moore Foundation. With the grant of 800,000 euros, Briegel will set up a new research line into studying symbiotic interactions on the nanoscale.

Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.

The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…

As of February the SBB team has expanded. Simcha Jong has joined the team as a Professor and Director of Science Based Business.

Seventeen Leiden University scientists appear on the 2019 Highly Cited Researchers list, which was announced on 19 November by Clarivate Analytics.

Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.

Gerard van Westen has received the KNCV Gold Medal, the most important Dutch award for chemists under 40. 'It's a huge honour,' says the professor of AI and medicinal chemistry. 'I am now part of the group of people I was always impressed by.'

Students searched for MSc Internships under the following topics: 1. Understanding temporal variability in functional biodiversity and 2. Characterization of engineered nanoparticles in aquatic organisms: Gold nanoparticles and carbon nanotubes

Antibiotic resistance is one of the major threats to human health. This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht, with many of the stakeholders in the field present.

Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.

Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.

How do I conduct research? How do I structure, conduct and record what I’ve thought of and done? The Bio-Pharmaceutical Sciences Programme didn’t just want students to perform a series of tests for the Cellular Biochemistry practical course. After a complete re-vamp - ‘From traditional cookbook lab…

Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

With its Green Deal The European Union has set itself much-needed ambitious climate goals. But the energy crisis and geopolitical tensions are making these difficult to achieve. Seven researchers from the Leiden-Delft-Erasmus Universities (LDE) alliance have written a white paper offering solutions.

Bringing the theoretical world of mathematics and computer science to more applied research areas. That is what Daan Pelt, assistant professor at the Leiden Institute of Advanced Computer Science (LIACS) is trying to achieve with the methods he is developing as a solution to challenges in image proc…

The Leiden Academic Centre for Drug Research (LACDR) received no less than three awards during the Figon Dutch Medicine Days. Bas Goulooze won the PhD Prize for best PhD candidate, Natalia Ortiz Zacarías and Huub Sijben both received a poster prize. ‘Scientists must be able to communicate their research…

The project MiCRop receives 20.3 million euros from the Gravitation programme of the Dutch Research Council (NWO). MiCRop will unravel the microbial community around crops. This knowledge will help to develop more sustainable crops that require fewer fertilizers and pesticides. Leiden professors Jos…

Want to find out how to assemble a human skeleton? Do you know what chemistry can be found around you? And are you easily fooled by fake news? Discover this and more at our Science Fair on 3 October.

The European Union has awarded a COFUND grant to a consortium of researchers from the universities of Groningen, Leiden and Eindhoven for a collective fellowship programme called ‘oLife’. The 6 M€ programme, which is co-financed by the participating universities, will recruit and train 18 post-doctoral…

‘Working in Leiden is a dream come true.’ Ákos Kovács studied in his birth country Hungary and worked in Germany, Denmark and Groningen. As professor of Microbiome Ecology at IBL, he immediately started working together with his new colleagues to make discoveries about the versatile bacterial species…

Medicines are becoming increasingly precise and innovative, but at the same time increasingly expensive. With their innovations, it is up to universities to increase competition, thus causing prices to drop. This is what newly appointed Professor of Biomolecular Analysis Hubertus Irth argues. His inaugural…

Harvesting rice from the same field, without planting new rice plants? A discovery may bring this scenario closer. Leiden scientists have discovered a gene that allows annual plants to grow after flowering, instead of dying. Publication on 13 April in Nature Plants.

Emeritus Professor Ben Lugtenberg edited a book on “Principles of Plant-Microbe Interactions” together with Paul Hooykaas, Eddy van der Meijden and Jos Raaijmakers, all from the IBL.

A large multidisciplinary team of experts on ageing has secured over €8.5m for a major study of which factors and solutions promote healthy ageing and increase vitality. The LUMC and the Leiden Academic Centre for Drug Research (LACDR) are two of the centres involved in this national research projec…

Paramagnetism. An obscure occult practice? No. It’s one of the newest scientific methods for mapping the behaviour of proteins with great precision. Marcellus Ubbink has been awarded 3 million euro by NWO and Leiden University to purchase a very powerful instrument. The goal: to acquire greater insight…

Biological chemist Nathaniel Martin is going to test an alternative antibiotic that can combat common resistant bacteria such as MRSA. For this purpose, he will receive 350,000 euros from the NWO's NACTAR programme. ‘We want to know how safe and effective our antibiotic is in a realistic situation.’

Andreas Bender, Assistant Professor for Medicinal Chemistry in the Medicinal Chemistry Division of the Leiden / Amsterdam Center for Drug Research, received the

‘If we don’t start talking about this, who else will?’ This is what Arjan Lankester, paediatrician/immunologist at the Leiden University Medical Center (LUMC) and Professor of Paediatrics, thought when it seemed that various extremely effective gene therapies for rare diseases would no longer be available…

Genetically modified organisms (GMOs) could be useful allies in the fight against critical environmental problems. Could because the use of GMOs is strictly regulated at the moment. A Leiden student team is now trying to make these GMOs safer with the aid of an ingenious lock.

An external visitation committee gave the Institute of Biology Leiden (IBL) an outstanding assessment. In terms of research quality and relevance to society, the IBL gets the highest score: excellent. The increase with five new female professors also receives praise from the committee.

It's pretty hard to spot a single 5 nanometer particle. Leiden physicists pulled it off by turning a 120 nm gold rod into a detector.

In her inaugural lecture on 11 September, Miranda van Eck, Professor of Cardiovascular and Metabolic Therapeutics, addressed her research related to developing medications to keep our blood vessels clean.

For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…

An international team with researchers from Leiden revealed how a bacterium repurposed an internal system to control its movements. Movement control is very important in host invasion, which can lead to disease. Publication on 27 April in Nature Communications.

Professor Annemarie Meijer and several students explained to more than 8000 visitors the zebrafish as a model for research during the National Weekend of Science (3-4 Oct) at Science Center NEMO in Amsterdam.

Immediately connect with the needs of industry with your master’s degree. The new course Practical Aspects of Quality Management in Pharma and Biotech provides just that. The LACDR and LUMC set up the course together with the Biotech Training Facility, located at the Leiden Bio Science Park. The first…

On November 1st, 2024, professor Johan Kuiper will retire and be appointed as emeritus professor at Leiden University. Since November 2008, Johan Kuiper was professor of Therapeutic Immunomodulation in the division of, at that time, Biopharmaceutics (which later on became the division of BioTherapeutics)…