Leiden evolutionary biologist Maurijn van der Zee has co-operated on an enormous international project to describe the genetic material of the pea aphid Acyrthosiphon pisum. The more than 100 authors involved in the project have published their findings in the online magazine PLoS Biology.

A night sky of more than 40 petabytes in size, simulating young star clusters and understanding how the body inhibits viruses: three Leiden projects have received computing time on one of the national computer systems.

All acute care staff at Leiden University Medical Center have received their first and sometimes even their second dose of the coronavirus vaccine. But how long will you be protected after vaccination and what does the genetic material of the virus do in the vaccine? Our virologists Ann Vossen and Leo…

Plants that grow in patterns of stripes on the edge of deserts, plankton that live on the sea bed or oscillate in the water, and melanomas that spread throughout the body. Mathematician Lotte Sewalt discovered the common elements in these three systems. PhD defence 8 September.

A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.

The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.

One of them turned out to be two thousand years old. And older giant barrel sponges appear to have a faster rate of cell division, unlike us. They produce antibiotics and much, much more. Lina Bayona Maldonado studied how the differences in such factors as age or oceanic depth affect the production…

An international team of researchers, involving members from the ERC Synergy project NEXUS 1492 based at the Leiden University, the Universities of Oklahoma, Copenhagen and York reveal challenges when studying ancient microbiomes in a recent issue of Scientific Reports.

New research published in the Journal of Leukocyte Biology suggests that these changes to the behavior of the immune system are persistent and can continue even after diet is improvedAlmost everyone knows that improving your eating habits will most likely improve your health. What most people may not…

Herman Spaink knows of many substances that may help combat tuberculosis. Lab space to study them safely is very limited in Leiden. A brand-new lab at Universitas Gadjah Mada in Indonesia will soon provide a solution. About time, says Spaink, ‘The disease is on the rise and is becoming less sensitive…

Both Leon Jacobse and Thom Hersbach from Marc Koper's research group obtained their PhDs cum laude. They both investigated changes on the surface of a platinum electrode. Jacobse studied this at a positive voltage, Hersbach at a negative voltage. Platinum has the potential to convert renewable energy…

As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…

Do young people who want to change gender have the unconditional right to medical treatment? Pediatric Endocrinologist Martine de Vries, who is also Professor of Medical Ethics, treats transgender children and adolescents. She will discuss this in her ‘Pride Talk’ on 18 September.

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

How safe are the nanoparticles in transparent sunscreen, anti-odour socks and bacteria-resistant plasters? Although microbes are present on all organisms, the tools that estimate the safety of nanomaterials still hardly take them into account. Bregje Brinkmann explored the role of these microbes during…

Freezing bacteria super fast to gain a true-to-nature image of the internal and external structure. Ariane Briegel Professor of Ultrastructural Biology came to Leiden specially to carry out this research. Leiden University is one of the few institutes in the world to have the necessary equipment. Inaugural…

Masses of hamburgers, steaks, cheese and a lot of eggs: Americans love their animal products. But researcher Oliver Taherzadeh discovered that only a relatively small group of high-volume consumers need to modify their diet to achieve an enormous environmental gain.

Professor of Pharmacochemistry Ad IJzerman has won the Nauta Award for his years of research into signal processing proteins that are interesting for the development of new medications: G protein coupled receptors. The prize is awarded every two years for services to pharmacochemistry and chemical b…

Martina G. Vijver has been appointed professor of Ecotoxicology at the Institute of Environmental Sciences of Leiden University with effect from 1 December 2017.

The quality of vaccines is still often tested by using laboratory animals. That has to change, according to researchers from Leiden University and the vaccinological institute Intravacc. Together they went searching for a test method that makes animal testing unnecessary. The first promising results…

On 1 August, Lars Jeuken started work as Professor of Biophysical Chemistry at the Leiden Institute of Chemistry (LIC). His research is at the intersection of biology and chemistry, but also involves physics and nanotechnology. Jeuken: ‘By linking nanoparticles to proteins and bacteria, we want to convert…

Sebastian Pomplun manages to reach proteins with drugs even where this was thought impossible. That is why he and his research group have been allowed to join Oncode Institute. With nine others, he had been selected from 72 applicants to contribute to Oncode Institute's mission: to accelerate breakthroughs…

Of the 87 Vidi research subsidies awarded by NWO, five have been awarded to Leiden researchers. This represents almost 6 per cent of the successful applications.

A delegation from Leiden University will be visiting Mexico from 21 to 25 October. The visit aims to strengthen the ties between Mexican universities and Leiden University.

Graphene floating on water does not repel water, as many researchers believe, but rather attracts it. This has been demonstrated by chemists Liubov Belyaeva and Pauline van Deursen and their supervisor Grégory F. Schneider. Publication in Advanced Materials.

Cardiovascular diseases are the leading cause of death across the world. Professor Johan Kuiper of Leiden University carries out research to develop a vaccine for arteriosclerosis, which is the main cause of cardiovascular diseases. With the aid of a European research grant of six million euros he is…

Physicists, including Leiden researcher, Sanli Faes, have devised a new technique for studying processes at microscale rapidly and extremely precisely. This new method will make it easier to develop antiviral medication. And it doesn’t stop there. Publication in ACS Nano.

Testing chemical substances without using animals. It seems a utopia, but a European team is going to develop a way to make this a reality. The RISK-HUNT3R project, led by Leiden professor Bob van de Water, received 23 million euros from the European Commission for this purpose. The project was launched…

Pharmacologist Walter Boiten developed a new method to determine the amount of lipids in a person's skin. With this method he tested the effects of a new cream he developed for eczema patients. The first results are promising. Boiten defends his dissertation on 15 January.

The Science faculties of Universitas Indonesia (UI) and the Universiteit Leiden signed agreements on Tuesday April 12 that will strengthen cooperation between the Faculties. The agreements were signed at the closing of a two day visit of a delegation from Indonesia. The delegation, which was led by…

Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.

If it’s up to PhD student Guangsheng Du, patients don’t need to worry about big needles anymore. At the Leiden Academic Center for Drug Research (LACDR), he studied the use of microneedles and nanoparticles as a new vaccination system. ‘I want to create a more patient-friendly delivery method.’ He defends…

PhD candidate Jiangnan Ding explores how you can design a thick slab of rubber in a way that it might act as a mechanical computer bit. This so-called mechanical metamaterial is pushed in a specific way to change its shape. ‘With a very simple material, we might be able to do simple calculations in…

Professor of Human Genetics Willeke van Roon will give her inaugural lecture on Monday 28 March entitled: ‘Translational research, where small parts make the bigger picture.’ She will emphasise how university medical centres should take responsibility for finding treatments for very rare diseases.

Leiden's iGEM team has won high honours at the Grand Jamboree in Paris. The biology students came second in the Overgraduate category with their project PHAse Out. They also took home awards for Best Biomanufacturing Project, Best Wiki and Best Entrepreneurship as well as a Gold Medal. To top it all…

Collaborating in drug discovery and health research was the goal of a visit to the Leiden Bio Science Park on 14 May by a Swedish delegation including His Majesty King Carl XVI Gustav of Sweden. The delegation visited Leiden University’s Faculty of Science.

Leiden researcher Dr Ben Zonneveld has determined the size of the genome - the amount of DNA per nucleus - of wild tulips. His conclusion is that there are more than 87 wild species. Various possibly new species have been discovered.

Recently, our respected and talented former colleague Bente Hilde Bakker passed away after a long and brave fight with illness. She received her mathematical training at the Vrije Universiteit in Amsterdam and also obtained her PhD there under the supervision of Jan Bouwe van den Berg and Robert van…

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Leiden biologists have shown that a gene present in plants, animals and yeasts does play an important role in plants, although for years the gene was considered unimportant. It turns out the gene plays a crucial role in the development of vascular tissue in plants. Publication in Nature Plants on 11…

The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

The group structure of Jihadist networks changes rapidly, which makes it difficult to monitor them. This is the finding of research by criminologist Jasper de Bie. PhD defence 14 April.

Discover budding creators, artists and researchers at the Night of Discoveries art and knowledge festival. And many researchers from Leiden University are taking part.

Biotechnological developments are moving fast. From genetically modified plant varieties we are now moving to cultured meat. These developments require moral interpretation - and they get it in the form of art. Lotte Pet wrote a dissertation about it.

Two research groups involving Leiden University have been awarded a major European grant, the ERC Synergy Grant. This for research on the development of membranes that can clean water and purify medical drugs and research on the biological clock in certain bacteria.

Using photosynthesis to generate energy, or using enzymes to effectively produce biofuel; Leiden chemists Huub de Groot en Hermen Overkleeft have both obtained an NWO TOP funding for their pioneering research. With the money they can take on new PhD students.

Winning a prestigious award for PhD researchers, even before you have your doctorate: that's what Yascha van den Berg managed to do with his research proposal on alternatively spliced tissue factor, a protein that may be involved in tumour growth. Van den Berg: ‘It all started as a Friday afternoon…

A coronavirus booster shot provides a better immune response against COVID-19 than a single vaccine dose. mRNA boosters are the most effective upon receiving Janssen. These are the results of a collaborative study between several organisations, including the Leiden University Medical Center (LUMC).…

An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…

Four scientists from Leiden University have each been awarded a Starting Grant by the European Research Council (ERC). This grant, worth up to two million euros, gives researchers the opportunity to head up a research team for five years.