254 search results for “vaccine” in the Public website
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RESTORING T-CELL HOMEOSTASIS BY IN VIVO MANIPULATION OF DENDRITIC CELLS
The loss of T-cell homeostasis and tolerance towards self-antigens is the underlying cause of autoimmune and inflammatory diseases like atherosclerosis, rheumatoid arthritis or type I diabetes. Traditionally, the treatment of these diseases consisted on systemic immune suppression, which can entail…
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Student projects
Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…
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Key publications
Key publications of the Barz Lab
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Immunity, Infection and Tolerance
Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…
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Archive
View all our Alumni newsletters below.
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Resetting the immune system to cure diabetes and rheumatism
In autoimmune diseases such as rheumatism and diabetes the immune system attacks autologous proteins. Leiden researchers are trying to discover how this comes about.
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Science Experience Tours
During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Alternatives to animal experiments: Replacement, Reduction and Refinement
We aim to conduct as few animal experiments as possible. We are continually exploring methods to Replace, Reduce, and Refine animal experiments, commonly referred to as the three Rs. Additionally, we assess each study to ensure the implementation of the 3Rs has been maximised. The Animal Welfare Body…
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Clashing fundamental rights in KLM labour dispute
Can the KLM reject an applicant for a job as a pilot or stewardess if they refuse to get vaccinated against Covid-19? Or put more broadly: can the employer of a new employee demand that they are vaccinated? Those questions were at the centre of court proceedings brought on Thursday by the Dutch Airline…
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Fall of Misinformation Series: Ionica Smeets
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
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Fall of Misinformation Series: Suzan Verberne
Misinformation spreads easily and fast. It gets presented as news, whereas actual news gets dismissed as fake. Conflicting streams of information allows all sides to cherry-pick whatever is most comfortable, boosting degrees of confidence and confusing the deliberation of both politicians and voters.…
- Articles
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Malaria researchers from all parts of the world in Leiden
Researchers from all parts of the world will be in Leiden from 2 to 4 May for a major malaria conference. The Leiden University Medical Center (LUMC) is organising a two-day workshop on how vaccines can be tested safely in humans.
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The immune system: step it up or slow it down?
When foreign matter enters our body, our immune system has to make a choice whether or not to go on the attack. There are times when the system goes wrong, and we end up with an illness or an allergic reaction. Researchers at LUMC are trying to steer the immune system. The dossier on Immunity, Infection…
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A chemical connection that affects your immune system
A group of chemists, that includes Sander van Kasteren and Hermen Overkleeft, has discovered that azides, a certain type of chemical compound, can determine whether or not T cells respond to or ignore a vaccine. Their discovery is set to be published in Angewandte Chemie.
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The quest for new medicines against tuberculosis
Can drug screening for tuberculosis treatment be made more efficient?
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Research in Africa reduces health spending and prevents diseases of affluence
Health workers have always sought ways to fight disease in vulnerable groups in the population. It is now clear that such research also benefits more prosperous countries. African worm infections and innovative thermometers have shown Leiden researchers how to fight diseases of affluence and keep health…
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Research
Research at the SBC group is comprised of the following research themes:
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Our man in Jakarta keeps the institute running from Venlo
The COVID-19 pandemic forced many staff of Leiden institutes abroad to leave their posts in a hurry. How is the KITLV Jakarta team doing now? Director Marrik Bellen talks about the turbulent times for this Leiden institute and its staff. And can we learn anything from the Indonesian approach?
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From in-person lectures to a first-class degree: our year on social media
Covid year 2021 might have felt somewhat less strange than the year before, but the virus still left its mark on University life and our students and staff. Fortunately there was also room for research, visiting dignitaries and in-person classes. And our social media accounts weren’t only about covid…
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How do we maintain a healthy biological clock?
During Seeing Stars Leiden all the lights around Leiden Observatory will be switched off for an hour. The more lights that go out, the more stars we’ll be able to see. For the LUMC, this is the perfect moment to think about our biological clock, the topic researchers from the BioClock consortium are…
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Six Leiden researchers receive ERC Starting Grant
Six researchers from Leiden University have received an ERC starting grant. This grant of on average 1.5m euros will enable the researchers to launch their own project, form their own research team and develop their best ideas.
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Blog Post | Diplomacy’s Response to the Coronavirus (Part II)
The previous blog post in this series discussed the role of international diplomacy during the coronavirus crisis. This post focuses on diplomacy and its challenges in post-corona times. Specifically, the blog post argues that diplomats will face a range of challenges following the Covid-19 pandemic…
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Anne Meuwese and Bart Custers in Trouw on Covid apps
The more people are vaccinated, the more society can slowly reopen. Technological developments, like the Covid passport and other apps, can play a role in this. Artificial Intelligence could help greatly in developing the vaccine passport and the Covid-19 exposure notification app, Anne Meuwese and…
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GP in the Bible Belt: does God play a role in consultations?
Jaïr van Rhenen studied Medicine in Leiden and is now a GP in the largely religious Veenendaal. Before this, he worked as a tropical medicine doctor in Lesotho. ‘If you have the prospect of an afterlife, you often respond differently to illness.’
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Test certificate could help reopen society, but at what cost?
On 11 May the House of Representatives voted in favour of a law that will enable some sectors to reopen sooner than planned with the aid of test certificates. Political philosopher Josette Daemen is critical of the new legislation. ‘Just because we get used to measures doesn’t make them desirable.’
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In Memoriam professor Wim Jiskoot (1961-2021)
Afgelopen zondagavond, 22 augustus, is na een kort ziekbed onze zeer gewaardeerde collega professor Wim Jiskoot, Hoogleraar Technologie van toediening van medicijnen, overleden. Wim werd twee weken geleden onverwachts geconfronteerd met het feit dat hij een vergevorderd stadium van kanker had, waarvoor…
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Third prize awarded to Pim Schipper for oral presentation at GPEN conference
Pim Schipper has won the third prize for his oral presentation during the tenth biennial meeting of the Globalization of Pharmaceutics Education Network (GPEN), which was held from 27 – 30 Aug 2014 at the University of Helsinki, Finland.
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Cairo Institute Director: ‘I’m keeping the ship afloat’
In March 2020, the Netherlands-Flemish Institute in Cairo suddenly had to repatriate 57 students to the Netherlands and Flanders. Director and Arabic specialist Rudolf de Jong decided to stay in Egypt. ‘A lot of the work carries on.’
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Hester Bijl: ‘On-campus teaching is a big step forward, so take care’
‘We’re going to see each other again on campus. We’re so pleased, but we do have to say safe.’ Rector Magnificus Hester Bijl is looking ahead to the new academic year, which begins on 6 September. No more 1.5m distancing, but we do have to take responsibility for other people’s safety.
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Bio Science Park generates thousands of jobs and millions of euros for the Leiden region
The Leiden Bio Science Park (LBSP) is very important not only for the city of Leiden but also for the Leiden region and the Netherlands as a whole. This is the finding of an investigation conducted by the Leiden-Leiderdorp Audit Committee. The large-scale development of the LBSP in recent years has…
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Major Expansion Leiden Quantum Computing
The 18.8 million euro NWO Zwaartekracht grant for quantum software which Amsterdam, Delft and Leiden landed collectively, means for Leiden University among others the appointment of two new permanent scientific staff members, who will each form their own research group, divided among Computer Science,…
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Statistics & Data Science (MSc)
The master’s programme Statistics & Data Science provides students with a thorough introduction to the general philosophy and methodology of statistical modelling and data analysis. The programme has two specialisations: Data Science and Statistical Science.
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Vision and Mission
The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.
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New term dates for the Dutch language course
Important note: upon careful consideration, we have decided to resume our Dutch language courses.
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A Harmonised EAC COVID Pass to Re-Kindle Intra-Regional Trade
COVID-19 poses a significant barrier to intra-regional trade within the EAC, causing interminable hold-ups at the internal borders.
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Pharma company Janssen expands premises on Leiden Bio Science Park
Pharma company Janssen has begun construction on a new office and lab building at the Leiden Bio Science Park. The first pile of the 13,500 square metre building has been driven into the ground.
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Vidi grants for eight researchers from Leiden University
Eight scientists from Leiden University have been awarded a grant by the Dutch Research Council (NWO). With this Vidi funding, the researchers can set up an innovative line of research and further expand their own research group over the next five years.
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Corona research crowdfunder attracts media attention
Within a month, the Wake Up to Corona crowdfunding campaign had already raised 600,000 euros for corona research in Leiden. The goal is to raise enough money for the LUMC to set up a second laboratory that is safe enough for research into the new virus. The initiative has not escaped the attention of…
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‘Value to society has our full attention’
Rector Magnificus Hester Bijl can see dilemmas but above all opportunities in the search to increase the societal value of research in Leiden.
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Introducing: Monika Baar
Monika Baar started working in Leiden in September 2015. She's currently the project leader of the ERC Research Project 'Rethinking Disability'.
- Blog Posts Archive
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Prof. dr. W. Jiskoot listed in Thomson Reuters 2015 Highly Cited Researchers
The list of highly Cited Researchers identifies the world’s most influential contemporary researchers across 21 scientific fields. Prof. dr. W. Jiskoot is cited one out of three in the field of Pharmacology & Toxicology in the Netherlands, and as one of four of all categories in Leiden.
- Program in English
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Support the LUMC’s corona research
Scientists at the LUMC are working hard on potential virus inhibitors, antiviral screening and a treatment for COVID-19. SteunLeiden.nl has started a crowdfunding campaign for this research, under the hashtag #wakeuptocorona. Professor of Virology Eric Snijder explains why this is desperately needed…
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Professor Ben Lugtenberg received ‘The Arima Award for Applied Microbiology’
Emeritus Professor Ben Lugtenberg received ‘The Arima Award for Applied Microbiology’ from the IUMS (International Union of Microbial Societies) for his life-time contributions to this field.