210 search results for “target therapy” in the Staff website
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AI model accurately predicts endometrial cancer recurrence
Researchers from the Leiden University Medical Center (LUMC) have developed an AI model that accurately predicts the risk of endometrial cancer recurrence.
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‘Hoogsensitiviteit is geen klinische diagnose, maar een persoonlijkheidskenmerk dat je kunt benutten’
Do you often feel drained after a day at the office? The new SPS Monitor measures how sensitive you are to various stimuli. Psychologist Véronique de Gucht developed the questionnaire. 'I want to demystify high sensitivity.'
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Four NWO Open Competition grants for Leiden researchers
Four researchers from Leiden University have been awarded NWO Open Competition grants in the Science domain. This is for research into subjects such as immune cells in tumours, antibiotic resistance and magnetic semiconductors.
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Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
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Silver and light: a powerful combination with the potential to save lives
Packages of DNA strands containing silver, measuring just two or three nanometres in size. Leiden physicists Donny de Bruin and Dirk Bouwmeester create these packages, which can enter living cells on their own. They then activate the silver with light, causing the cells to break down. This could, in…
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Funding for four Leiden studies in the fight against arthritis
Four researchers from Leiden University will receive funding from arthritis foundation ReumaNederland over the next five years. This should facilitate long-term research into arthritis.
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Burnout First-aid Kit
Personal development, Working effectively
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IBL Spotlights - Development & Disease
Lecture
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Psychology Connected: Depression and resilience
Conference
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Family Matters
PhD defence
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What Works in Suicide Prevention? Lessons from the 113 Helpline
Lecture
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European subsidy for Ellen de Bruijn: ‘Hormonal fluctuations in women have been ignored for too long in brain research’
Psychologist Ellen de Bruijn studies the effects of hormonal fluctuations on behaviour and on the brain over a woman's life course. With an ERC Consolidator grant, she and 3 PhDs and a postdoc will further her EEG research on the different stages at which girls and women experience strong hormonal f…
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Psychologists at Lowlands Science: can virtual reality trigger a psychedelic experience?
Fantastic plants, dizzying patterns and pulsating sounds: researchers from Leiden are going to study the effects of a simulated psychedelic trip on the mind and body at Lowlands Festival. Why might this be interesting for therapies?
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Depressed adolescents gain little benefit from eye contact with their parents (although connection is so very important)
Eye contact between parents and children improves their mood and increases feelings of connectedness on both sides; but not in the case of depressed adolescents, Mirjam Wever discovered. Where the parent-child bond has been disrupted, it can be strengthened not only with therapy for the child but also…
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What works in suicide prevention? Lessons from the 113 Helpline
113 Suicide Prevention gave a guest lecture about suicide prevention at the Spanish Steps in Wijnhaven
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Combating antibiotic resistance together
Antibiotic resistance is a common problem among patients. The European Project TIPAT trains pharmacologists, microbiologists and immunologists of six universities in interdisciplinary thinking. The ultimate goal is to develop better treatment guidelines to combat resistance. Coen van Hasselt of the…
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Eight professors receive double appointment simultaneously
Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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De nieuwste onderzoeken in kaart op de publieksdag Brein & Recht
How does our brain interpret traces of evidence? Can someone who is suffering from brain damage be held accountable for criminal offences? And should it be possible to adjust a criminal’s behaviour with deep brain stimulation? These questions were addressed during the Public Scientific Day Brein & Recht…
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Nerve stimulation effective in patients with untreatable cluster headaches
Extremely painful chronic cluster headaches – sometimes referred to as ‘suicide headaches’ – can be prevented by stimulating the occipital nerve in the back of the head, according to research conducted by Professor Emeritus of Neurology Michel Ferrari from Leiden University Medical Center (LUMC). The…
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Medical Delta professor Ariane Briegel: 'I love working with people from different backgrounds'
Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…
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Life after the Grand Jamboree: Wrapping-up iGEM
‘A challenging rollercoaster, but also a very bonding and insightful experience,’ that’s how the team of iGEM Leiden 2022 wraps up their participation in the iGEM contest. The contest for synthetic biology climaxed during the Grand Jamboree in Paris. The team ended up in the top 10 of over 360 teams…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Perspective for people with borderline personality disorder
‘Raising awareness of the disorder is crucial since borderline personality disorder (BPD) still faces considerable stigma ’, says Anne Krause-Utz (Clinical Psychology) . Together with an international team of excellent scientists, Krause-Utz provides an update of current knowledge about this disorder,…
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Alumnus Anne Speckens opened a mindfulness centre in Nijmegen
Professor of Psychiatry Anne Speckens studied medicine in Leiden and did her psychiatry training there too. She opened the Radboudumc Center for Mindfulness in Nijmegen. What does she do there and how does she look back on her time as a student?
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Nutrition and fasting for the brain: why the Keto diet shows promise
Autism, Alzheimer’s, and bipolar disorder: can the development of these mental health conditions be influenced by the ketogenic diet? Increasingly, research suggests it might. 'For those it helps, it can be life-changing,' says neuroscientist Eline Dekeyster.
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Leideners and researchers learn from each other at the Science Market
3 October University has become something of a tradition: a bit of science among the Leidens Ontzet celebrations. During the new and improved edition, the WetenschapsWarenMarkt (Science Market), visitors spoke to researchers about the nitrogen problem, making organs and the city’s connections with A…
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‘Children’s healthcare rights deserve more attention’
‘Children’s rights are somewhat of a poor relation’, says Professor of Law and Health Mirjam Sombroek-van Doorm. In her inaugural lecture, she will emphasise how more attention needs to be paid to children’s rights in current thinking on law and health.
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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It is not easy to simplify your research
Defending your PhD research in front of nearly 300 elementary school students: that was the challenge faced by PhD candidates Jo-Anne Verschoor and Marinka de Willigen during the VUURVLIEGEN competition organised by the Centrum JongerenCommunicatie Chemie (C3). After an exciting competition, the children…
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'It’s the complexity of this group of patients that makes the challenge of improving their quality of life so interesting’
Dialysis patients experience a range of physical and mental symptoms that interact and influence each otherIn her doctoral research, psychologist Judith Tommel wanted to find the optimum approach to help these dialysis patients improve their quality of life. ‘We need to make sure we avoid excluding…
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New SPARXS technique reveals DNA behaviour at unprecedented speed
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…
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Can extreme antisocial behaviour be traced back to the brain?
The brain structure of young people with conduct disorder differs significantly from that of their typically developing peers. This is the conclusion of an international study that analysed more than two thousand MRI scans, recently published in The Lancet Psychiatry. Dr Moji Aghajani, one of the principal…
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How to develop cancer drugs with less side effects
Lecture, Tuesday Talks: Science Insights
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Veni grants for 21 researchers from Leiden University
An impressive 21 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).
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Silicon pore optics for high-energy optical systems
PhD defence
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Inge Schilperoord nominated for the Dutch Libris Prize 2016
Psychology alumna Inge Schilperoord works as a forensic psychologist in the Pieter Baan Centre, a psychiatric observation clinic. Her debut novel 'Muidhond' about a man struggling with his paedophilic tendencies, has received the Bronze Owl 2015 for best Dutch debut novel. Schilperoord: 'The detective…
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How e-coaching helps people with chronic kidney disease to live more healthily
An e-coaching programme helps people with chronic kidney disease, particularly in areas that patients themselves want to work on. ‘A healthy lifestyle is important for patients with kidney disease: it can slow down the loss of kidney function and there will be fewer complications,’ Katja Cardol explains…
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Andrea Evers’ role in the new Executive Board of PsychologyAndrea Evers’ role in the new Executive Board of Psychology
The new Executive Board of the Institute of Psychology became effective on 1 February 2022. Scientific director Andrea Evers tells us where she gets her energy from.
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Ten Leiden researchers awarded ERC Starting Grants
Ten scientists from Leiden University will receive a Starting Grant from the European Research Council. This will allow them to launch their own project, form their own research team and implement their best ideas.
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The Pursuit of Competence: Why our students need more meaningful challenges, not less.
The Leiden Academic Centre for Drug Research (LACDR) is closely connected to the education of our biopharmaceutical students, providing both courses and immersive internship projects. Among these is the Bachelor Research Project (BOO), which offers many students their first real scientific experience…
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Leiden University celebrates curiosity at 449th Dies Natalis
How has evolution shaped our curiosity? And how does that curiosity ensure that we now have the technological ability to discover whether we are alone in the universe? This was all covered during the celebration of Leiden University’s 449th Dies Natalis.
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Regulation of autophagy-related mechanisms during bacterial infection
PhD defence
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Guest lecture by 113 on suicide prevention
Lecture
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Towards a Historical Contextualisation of the Ancient Egyptian Perspectives of the Inner Body, Sickness, and Healing
PhD defence
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Quantitative Pharmacology Approaches to Inform Treatment Strategies Against Tuberculosis
PhD defence
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Entangled Transformations: Hegemonic and Counter-Hegemonic Power Dynamics in Belarus
Lecture, Research seminar