408 search results for “neurodegenerative disease” in the Staff website
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Quality of life is sometimes more important to the elderly than a cure
Geriatrics needs to radically change. This is what Simon Mooijaart will say in his inaugural lecture.
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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Looking at the person beyond the blood clot
How can we improve the treatment of thrombosis, reduce the disease’s impact and spend less money while we’re at it? This is what Erik Klok, Professor of Internal Medicine and an internist, is researching. He will discuss it in depth in his inaugural lecture on 10 March.
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Skin researcher calls for multidisciplinary collaboration: ‘I want to pool expertise’
In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…
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Documentary film alumna Visual Ethnography on show at Pakhuis de Zwijger
Wilke Geurds graduated from the Visual Ethnography master's programme last year with her intimate and vulnerable documentary 'F*ck Endo. More than just menstrual pain.'.
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Carrot or stick: which is better motivation to exercise more?
Free cinema tickets or a step tracker paid for by your health insurance. Some insurers offer rewards to promote healthy behaviour. But does the threat of losing something like a deposit work better? And what do patients think? This is what PhD candidate David de Buisonjé researched.
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Medical Delta professor Jaap Harlaar: ‘This form of collaboration is in my blood’
Hundreds of thousands of Dutch people suffer from pain caused by knee osteoarthritis and the number is rising fast. Prof. Jaap Harlaar specialises in clinical biomechanics. His research is helping improve osteoarthritis treatment. Harlaar has been appointed Medical Delta Professor and now holds posts…
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LUMC researchers: high levels of lipids in blood protect against allergies
People with relatively high levels of lipids in their blood are less likely to develop allergic conditions such as eczema and asthma. These lipids cause genes that play a key role in allergic reactions to be less active. Researchers from the Leiden University Medical Center (LUMC) have published an…
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A good pedometer encourages physical activity - but not for everyone
eHealth can improve our lifestyle without the involvement of a healthcare provider. Talia Cohen Rodrigues investigated the possibilities for people with cardiovascular diseases. ‘People with a low socioeconomic status may be more difficult to reach with eHealth.’ She will defend her doctoral thesis…
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Fighting gliobastoma brain tumours with two grants
Few researchers see potential in research on glioblastoma, an incurable brain tumour. Alexander Kros brought together colleagues who are up to the challenge. European research funder ERC recently made 10.6 million euros available, a year earlier NWO provided 3 million euros. ‘In six years, we certainly…
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A computational tool that will transform bacterial genome analysis
Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.
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Young researchers looking for partnerships in Indonesia
A number of young researchers recently took part in a knowledge mission to Indonesia, aiming to build a lasting relationship with the country. How did they find the trip, what did they do, and how are they creating new connections with scientists in Indonesia?
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Not everyone has health goals top of mind
Preventing or delaying disease often requires lifestyle changes, which turns out to be difficult. Valentijn Visch and Sandra van Dijk are researching how to help people change their behaviour.
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Hanneke Hulst new Scientific Director Institute of Psychology
Prof. Hanneke Hulst has been appointed Scientific Director of the Institute of Psychology by the Board of the Faculty of Social and Behavioural Sciences. She will start on 1 February 2024 for a period of 3 years, succeeding Andrea Evers and interim director Serge Rombouts.
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Research projects launched into biodiversity in food and horticulture production
Two Leiden research projects that focus on increasing the biodiversity of Dutch production systems for food and ornamental horticulture have started thanks to funding from the Dutch Research Council's KIC research programme.
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eLaw publishes article in Computer Law & Security Review
In healthcare, gender and sex considerations are crucial because they affect individuals' health and disease differences. Yet, most algorithms deployed in the healthcare context lack close consideration of these aspects and do not account for bias detection. In their latest paper, Eduard Fosch-Villaronga,…
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University doctor
Leiden University is committed to creating a pleasant working environment for its staff. It may nevertheless happen that you find yourself unable to work due to a temporary or long-term illness or disability. The university doctors can help you reduce health risks and give you advice regarding your…
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University doctor
Leiden University is committed to creating a pleasant working environment for its staff. It may nevertheless happen that you find yourself unable to work due to a temporary or long-term illness or disability. The university doctors can help you reduce health risks and give you advice regarding your…
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International Symposium on Circuit Topology Organized by Leiden University
For the third consecutive year, LACDR organized the international symposium on topology, Circuit Topology III, on November 29, 2023. The event aimed to bring together experts from diverse fields, including mathematics, computer science, physics, chemistry, and biomedical sciences, to discuss cutting-edge…
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Henk-Jan Guchelaar temporary member of LUMC Board of Directors and interim Dean of the Faculty of Medicine
Organisation
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Jos Raaijmakers nominated for Huibregtsenprijs 2022
The research project of Jos Raaijmakers is nominated for the Huibregtsenprijs 2022. The researcher of NIOO, with a guest appointment at the Institute of Biology Leiden (IBL), is one of six nominees. On the Evening of Science & Society (Dutch: Avond van Wetenschap & Maatschappij), 10 October 2022, the…
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Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Medical Delta professor Marcel Reinders: ‘You need collaboration to make a real impact’
Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…
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In conversation with the head of the rodent facility
Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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Inaugural lecture: 'Connecting disciplines advances science and care’
On Friday 9 September, Jeanin van Hooft, Professor of Gastrointestinal and Liver Diseases, will deliver her inaugural lecture titled: 'The scope of connection'. She emphasises the value of collaboration and connection for scientific research. In addition, she pleads for more diversity; according to…
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Subsidy for development of tools for rheumatic diagnosis
Digital diagnostic tools should improve the diagnostic process of patients with musculoskeletal complaints, so that they can receive the right treatment more quickly.
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Draw on behavioural science for a healthy lifestyle
Healthy lifestyle campaigns are often unsuccessful. It is hard to get people to eat healthily or do more exercise. Behavioural science expertise should be drawn on at a much earlier stage in policy development, say twelve behavioural scientists in a position paper. They will present the paper to Maarten…
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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Dutch Cancer Society allocates funds to a mathematician: for treating Ewing sarcoma with the help of an app
If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…
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How to hijack natural destruction in cells: ‘We need to understand it through and through’
Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…
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Veni grants for 16 Leiden researchers
Sixteen researchers at Leiden University are to receive a Veni grant from the Netherlands Organisation for Scientific Research (NWO). These awards offer promising young researchers the opportunity to further develop their own ideas over a period of three years.
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Researchers from Leiden visit Indonesia on knowledge mission
A delegation from Leiden University recently embarked on a knowledge mission to various NGOs, universities and government organisations in Indonesia. New partnerships were formed and important knowledge exchanged, and researchers from Leiden gave guest lectures.
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Veni grants for 21 researchers from Leiden University
An impressive 21 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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ERC Starting Grants for five young Leiden researchers
Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
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Improving the treatment of pathogenic fungi. ‘The process is working, but not that well…’
Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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‘You can be both a good scientist and a parent’
How to combine being a mom and a career-oriented researcher? As member of the RISE junior board, postdoc Monica Varela wants to set an example. ‘It’s not always easy, but I want to show young scientists that you can continue your career when having a child.'
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Supergenes make bizarre traits possible
Within the same species of butterfly many different wing patterns can occur. How is this possible? According to researchers Ben Wielstra and Emma Berdan, of the Institute of Biology Leiden (IBL), the answer lies within supergenes. A supergene is a part of a chromosome that contains many strongly linked…
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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'There's nothing more we can do for you' - New publication on harmful communication in oncology
PhD student Janine Westendorp and her colleagues conducted literature research on what patients with cancer and their loved ones perceive as harmful communication from healthcare providers. The results were published in the journal Psycho-Oncology and are released as a poster to distribute to healthcare…
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Online database with two hundred local chronicle texts launched: A few years ago that wouldn’t have been possible'
Too expensive groceries, diseases suddenly breaking out: from the sixteenth to the nineteenth century, hundreds of people documented the world around them in chronicles. A significant number of these texts have been digitised in recent years. Professor of Early Modern Dutch History and project leader…
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A special part-time job: Susanne is vice president of the Youth Parliament for Water
Student of International Studies Susanne Reitsma has a remarkable passion: water. In April 2015, she was elected vice president of the World Youth Parliament for Water, in which capacity she works for worldwide access to clean drinking water and sanitation. What does Suzanne find so special about water?…
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.