2,045 search results for “lipid chair leon” in the Public website
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Immunity in atherosclerosis: novel assays, biomarkers and therapeutic approaches
Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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Historical Perspectives on Democracies and their Adversaries
This book, edited by Joost Augusteijn, Constant Hijzen and Mark Leon de Vries, explores how democratic regimes have dealt with anti-democratic forces in society, from the late nineteenth to the early twenty-first century.
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Sylvestre Bonnet
Science
bonnet@chem.leidenuniv.nl | +31 71 527 4260
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Mosquera Valderrama awarded a Jean Monnet Chair: 'Raise awareness of EU Standard of Tax Good Governance'
Last November, it was announced that the European Commission has awarded a Jean Monnet Chair to Professor of Tax Law Irma Mosquera Valderrama. She will use the grant to shape the EUTAXGOV project over the next three years.
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Ministry of BZK establishes two new professor chairs for the Kingdom
The Ministry of Home Affairs and Kingdom Relations (BZK) is establishing two new professor chairs for the Kingdom.
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Development of Comprehensive and High-throughput metabolomics techniques
A major goal of ABS research is to overcome one of the major bottle-necks in metabolomic research: the lack of a high-throughput infrastructure in which thousands of samples can be processed in a standardized and cost-effective way (max. a few tens of Euro’s per sample for a full metabolome profile).…
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Macrophages and atherosclerotic lesions
Macrophages and atherosclerotic lesions The infiltration of monocytes in the arterial wall, their differentiation to macrophages, and the subsequent accumulation of cholesterol in these macrophages initiate the process of atherosclerosis. We study the importance of specific genes in macrophages for…
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Hybrid vesicles
Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Sri Margana holds the Van Leur chair for early modern history of Indonesia
Dr Sri Margana succeeded Bambang Purwanto last September as professor in the Faculty of the Humanities. Margana is a specialist in the early modern history of Indonesia. The appointment will run for five years.
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Towards artificial photosynthesis on the lipid bilayer of liposomes
PhD defence
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mRNA and Drug Delivery with Lipid-based Nanoparticles
PhD defence
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A fatty solution for eczema
Pharmacologist Walter Boiten developed a new method to determine the amount of lipids in a person's skin. With this method he tested the effects of a new cream he developed for eczema patients. The first results are promising. Boiten defends his dissertation on 15 January.
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How democratic is our kingdom? New ministry chair for Leiden political scientist
When we talk about the Kingdom of the Netherlands, it is not just about the Netherlands. On the contrary: our Kingdom consists of no less than four countries, three of which are Caribbean islands. This structure is complex, to say the least. Although all countries are officially equivalent, in practice…
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Kraft Lab - Self-assembly in Biological and Soft Matter
Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.
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Respiratory-chain enzymes
Many metalloenzymes that are key to bioenergetics are membrane enzymes, with canonical examples the complexes I, II, III and IV in the mitochondrial inner membrane. To study these enzymes in a native-like lipid membrane environment, we aim to develop novel bioelectrochemical techniques.
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Professor Ann Skelton appointed as Children’s Rights Chair at Leiden University
Leiden University’s Executive Board has appointed South African Professor Ann Skelton as the new Chair of Children’s Rights in a Sustainable World as of 1 October 2022.
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Sofia Ranchordas appointed Chair European and Comparative Public Law at the University of Groningen
Sofia Ranchordas (1985) has been appointed Chair European and Comparative Public Law and Rosalind Franklin Fellow at the University of Groningen. She will start this position on October 1st.
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Vestert Borger chairs panel at the conference ‘The EMU at Twenty’
On Saturday 17 November 2018 Vestert Borger chaired a panel at the conference ‘The EMU at Twenty’.
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Rick Lawson to chair meetings of FRA Management and Executive Boards
The Executive Board and Management Board of the EU Fundamental Rights Agency will meet from 13 to 15 December, with Rick Lawson as Acting Chair.
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Legal Implications of Airport Privatization in India
On Thursday 24 November 2016 Moses George will defend his PhD dissertation ‘Legal Implications of Airport Privatization in India’. The defence will commence at 11.15 hrs, in the Academy Building of Leiden University. The Supervisors are Professor Pablo Mendes De Leon and Professor Brian F. Havel (DePaul…
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Ann Skelton elected as Chair United Nations Children’s Rights Committee
Professor Ann Skelton has been elected as Chairperson of the United Nations Committee on the Rights of the Child.
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Jean Monnet Chair for Moritz Jesse: Migration, Integration, and Non-discrimination in Europe
Dr Moritz Jesse, European Institute at Leiden Law School, has been awarded a Jean Monnet Professorship. From November 2023, Moritz will teach bachelor's and master's courses as part of his ‘Migration, Integration, Non-Discrimination in the EU’ project [MIND-EU]. At a later stage, Jesse’s Jean Monnet…
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Albert van Marwijk Kooy appointed Chair of GIP's Dispute Resolution Committee
The Pension Funds Dispute Authority (GIP) was founded on 1 January 2024. Albert van Marwijk Kooy has been appointed Chair of the Dispute Resolution Committee, which forms part of the GIP.
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Schuurmans to chair independent advisory committee on self-reliance and legal assistance
Those who seek justice do not always manage to find their way through the legal system. Yet the Dutch Legal Aid Act assumes that citizens are self-reliant and can stand up for their interests in cases that are not legally complex. However, in the childcare benefits affair in the Netherlands, this proved…
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Beryl ter Haar chairs roundtable at a conference on the European Pillar of Social Rights
22 September 2017 the second biannual conference took place organised by IAAEU of the University of Trier and the Hugo Sinzheimer Institute of Frankfurt. The theme of the conference was the European Pillar of Social Rights. Under the heading of the conference’s title, International Labour Law as a stimulus…
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Ymre Schuurmans chairs supervisory committee on judicial monitoring of Big Data
A study has been initiated at the instigation of WODC (Scientific Research and Documentation Centre) on the judicial monitoring of big data applications by government. The study is being conducted by TILT (Tilburg Institute for Law, Technology, and Society).
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Simone van der Hof chaired a panel on age verification in Brussels
On November 23, 2017, Professor Simone van der Hof chaired a panel on age verification in the digital world at the Safer Internet Forum 2017 in Brussels.
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Fatma Çapkurt appointed deputy chair of State Committee on Rule of Law
On 1 December 2023, Fatma Çapkurt was appointed as deputy chair of the State Committee on the Rule of Law.
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Giles Scott-Smith appointed Roosevelt Chair in New Diplomatic History
The Roosevelt Chair in New Diplomatic History is sponsored by the Roosevelt Institute for American Studies (RIAS) in Middelburg, and the new position further strengthens the connection between the RIAS and Leiden.
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Freya Baetens appointed to the Chair in EU External Economic Law
The Europa Institute is delighted to announce the appointment of Freya Baetens to the Chair in EU External Economic Law.
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New Special Chair Bas Rietjens with focus on intelligence in conflict situations
Prof. dr. ir. Bas Rietjens of the Dutch Defense Academy (NLDA) has been appointed Professor by special appointment Intelligence in War and Conflict at Leiden University’s Institute for Security and Global Affairs (ISGA). The appointment of Rietjens is the result of a more intensive collaboration between…
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Arnold Tukker named Chair of Industrial Ecology and Director of the Institute of Environmental Sciences
Prof. dr. Arnold Tukker will be appointed on 1 October 2013 as Chair of Industrial Ecology at the Faculty of Science of Leiden University. He will work at the Institute of Environmental Sciences (CML), and also become the new director of this institute.
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Alice Twemlow is the chair of the “Redesigning the Designer” congress at Het Nieuwe Instituut
In the light of today’s major changes and challenges, the congress on November 22 will focus on Redesigning the Designer while also taking some of the examples of more-than-human knowledge experimented with within Neuhaus as a starting point for a new network.
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Nico Schrijver appointed Interim Chair of Netherlands Institute for Human Rights
Nico Schrijver, Professor Emeritus of Public International Law, has been appointed Interim Chair of the Netherlands Institute for Human Rights. He will take up the position on 1 July 2024.
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Delicate Debates on Islam
Policymakers and Academics Speaking with Each Other
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Successful conference Kirchheiner Chair 'Government and citizens: A matter of trust'
On 1 September, the conference of the Kirchheiner Chair ‘Government and citizens: A matter of trust’ took place. In a packed hall in the beautiful Old Observatory of Leiden University, under the inspiring leadership of Willemien den Ouden, a debate was held on the role of the Dutch National Ombudsman,…
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Anne-Laura van Harmelen appointed to new chair Brain, Security and Resilience
Leiden University will appoint Dr Anne-Laura van Harmelen as Professor of Brain, Security and Resilience at the Institute of Education and Child Studies with effect from 1 September 2020. She will focus on the brain in relation to the development of transgressive behaviour and its prevention and tre…
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Bart Custers appointed as the new chair Law and Data Science
As of 1 July 2019, Bart Custers is appointed as Professor of Law and Data Science at Leiden University. The chair is established at eLaw, the center for Law and Digital Technologies at the Faculty of Law. Bart Custers will focus on the intersection of law and digital technologies, on the one hand on…
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Barend Mons appointed Chair of European Commission’s High Level Expert Group
Professor Barend Mons has been appointed Chair of the Commission High Level Expert Group
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Cathalijne van der Plas appointed to chair in Private International Law
Cathalijne van der Plas will become Professor of Private International Law (0.4 fte) at Leiden University as of 1 October 2021. She succeeds Prof. Sierd Schaafsma who has become a judge at the Supreme Court as of 1 May 2021.
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Joachim Koops awarded with Jean Monnet Chair on ‘The EU’s Role in Security and Global Affairs’
Joachim Koops, Professor of Security Studies and Scientific Director of Leiden University’s Institute of Security and Global Affairs (ISGA) has been awarded a ‘Jean Monnet Chair’ with a focus on ‘The European Union’s Role in Security and Global Affairs’ (EURISGA).
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Prof. Dr. Joost N. Kok appointed as panel chair in the research assessment of Tampere University of Technology
Prof. Dr. Joost N. Kok is panel chair in the research assessment of Tampere University of Technology (TUT), Tampere, Finland.
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The Right to Travel by Air of Persons with Disabilities
On Thursday 16 November 2017, Lalin Kovudhikulrungsri defended her doctoral thesis entitled ‘The Right to Travel by Air of Persons with Disabilities’. The supervisors are Professor P.M.J. Mendes de Leon and Professor A.C. Hendriks.
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Research
Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes: