The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

The Business Studies Seminar (BUSS) Series features invited scholars’ seminars on organizational, legal, and technological research. In 2024, the Organizational and Entrepreneurial Behavior, Technology and Innovation, and Corporate Governance and Strategy research groups will invite diverse speakers…

The Institute of Criminal Law and Criminology is located in the Kamerlingh Onnes Building (KOG).

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

This thesis introduces the concept of

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Conference

PhD defence

Education & outreach

Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

Bachelor and Master students of all chemistry related studies are more than welcome to take part in our research activities. We have projects on design and synthesis of biologically relevant compounds within an ongoing research project. Supervision, following the apprentice/teacher model, is one of…

Research training projects in the MCBIM group - Bachelor and master students of all chemistry related studies are more than welcome to take part in our research activities. We have various research projects, all in one way or another involving transition metal ions. Daily supervision in the laboratory…

Contact Biophysical Organic Chemistry/Solid State NMR

At Molecular Physiology we teach the following courses within the Leiden Institute of Chemistry's Chemistry and Life Science and Technology programmes.

Proactive zebrafish appear to have a much stronger wake-sleep rhythm than reactive fish. In the most reactive fish, rhythmicity appears to be lacking completely. This is shown with research by Leiden biologists, published in December 2018 in the journal BMC Biology.

ASLU 29 Maarten E.R.G.N. Jansen, Valentina Raffa (2015)

What are the precise identities, possibilities and current practice examples of the various time frames in music and what bearings do they have individually and in combinations on the speed of the music?

In this on-line dissertation, jazz saxophonist Dick de Graaf investigates a variety of compositional and improvisational models and techniques in contemporary jazz and Western art music, and discusses possible applications of these materials in current jazz practices.

Contact Supramolecular & Biomaterials Chemistry

Contact Theoretical Chemistry

Promotor: E. Bouwman, Co-promotor: S. Bonnet

SMR can be used to measure the mass of adsorbed protein to nanoparticles with a high precision in the presence of free protein.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

With a MSc in Chemistry you are well prepared for a wide range of career opportunities. The chemical industry is one of the largest contributors to economic prosperity worldwide.

The chemical industry must continue to innovate for a more sustainable, healthier society. The reseachers from the Leiden Institute of Chemistry (LIC) contribute by applying their knowledge to themes such as sustainability, energy and health.

The Leiden Institute of Chemistry organises and participates in several programmes for high school students and teachers.

Conact the Cellular Chemistry group

PhD defence

To be eligible for Chemistry at Leiden University, you must meet the following admission requirements.

Inaugural lecture

Fate and toxicity of copper nanoparticles was related to the water chemistry of the environment and pristine size.

Contact information & address

Research and education at the Leiden Institute of Chemistry is overseen by the Institute Board. The Board and representatives of the two research themes form the Management Team. The Scientific Council (WERA), the Institute Council (I-Raad) and the platform for PhDs and post-doctoral co-workers (LIC73)…

In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

Former Leiden Observatory PhD candidate Danna Qasim has won no less than two prestigious prizes with her thesis, titled 'Dark ice chemistry in interstellar clouds'. Qasim received the IAU PhD Prize from the IAU. The Astrochemistry Subdivision of the American Chemical Society (ACS) honoured her work…